骨骼畸形大鼠软骨细胞内胰岛素样生长因子-2的表达研究

目的 探讨胰岛素样生长因子-2(Insulin-like growth factor 2,IGF-2) 在骨骼畸形大鼠肢端软骨细胞内的表达规律.方法 应用光镜和透射电镜观测二(哑)英诱导的骨骼畸形大鼠足部软骨组织病理学改变.应用二(哑)英(1×10-8mol/L)干预体外培养的大鼠软骨细胞,采用RT-PCR及western 印迹杂交检测软骨细胞内的IGF-2 mRNA及蛋白质的表达水平.结果 15 μg/kg剂量的二(哑)英诱导实验组胎鼠出现多种畸形,内翻足、无尾畸形、腭裂等骨骼畸形发生率为33.3%.畸形胎鼠的肢端骨化中心发生带缩小,软骨细胞核内粗面内质网扩张,线粒体嵴紊乱.1×10-8mol/L剂量的二(哑)英使体外培养的大鼠软骨细胞内IGF-2 的mRNA及蛋白质的表达水平分别减少80%和60%(P＜0.05).结论 在二(哑)英诱导的骨骼畸形大鼠软骨细胞内IGF-2呈低表达状态.软骨细胞内IGF-2 的表达可能与骨骼发育密切相关.     

贵州环口螺科一新种记述(前鳃亚纲,中腹足目,环口螺科)

在整理贵州省贵阳地区陆生贝类标本时,经鉴定发现1新种,即奇异阿勇螺Arinia mirifica sp.nov..隶属于前鳃亚纲、中腹足目、环口螺科、阿勇螺属.对新种形态特征、栖息环境进行了记述,并对其近似种也进行了讨 论.     

二噁的主要来源、排放量及相关环境和健康标准

二(口恶)(口英)类化合物是一类氯代三环芳烃类化合物(PCDD/F),二(口恶)(口英)具有致癌性和类似生物激素的作用,极小剂量的二(口恶)(口英)就可能造成激素分泌的紊乱,影响青春期发育和引起     

盅口族线虫分类系统评述(线虫纲:圆线科)

对盅口族Cyathostominea线虫分类系统的研究进行了回顾和讨论,根据各分类学家的意见,笔者提出了盅口族线虫的分类系统,该系统以Lichtenfels等人（1998）的观点为基础,其不同点在于：1）将马线虫属Caballonema Abulasze,1937和柱咽属Cylindropharynx Leiper,1911从盅口族中移出,放入柱咽族Cylindropharyngea Popova,1952;2)Scialdo-Krecek(1984)描述的Cylicodon-tophorus reineckei应归属于副杯口属Parapoteriostomum Hartwich,1986.     

甘肃陆生贝类二新种(前鳃亚纲:中腹足目:环口螺科)

1998年4－5月作者在甘肃省南部地区考察,获得陆生贝类标本一批,经鉴定发现2新种,即大河腹皱螺Gastroptychia dahensis sp.nov。和清河倍唇螺Diplommatina qinghensis sp.nov.,隶属于前鳃亚纲,中腹足目,环口螺科,腹皱螺属,倍唇螺属。文中对新种形态特征,栖息环境进行了记述,并与近似种作了比较。     

中国南方海域鲎的种类和分布

The northern sea area of the South China Sea is situated between 107.5°～122.5°East longitude and 17°～25° North latitude with high temperature and a large quantity of rainfall which belongs to the oceanic climate of the torrid zone and subtropical zone. From September, 1994 to June, 1998,during the research on the species of Horseshoe crab within the scope between the south from North gulf and the north to Xiamen, choosing Xiamen, Shantou, Wuchuan, Donghaidao and Qishui as fixed positions and irregularly going to Xuwen and Suixi in Guangdong province and Fangcheng in Guangxi province, we found that there was only Tachypleus tridentatus in the northern sea area of the South China Sea and the sea area from Wuchuan to Xiamen, and found that there were two species of horseshoe crab which were Tachypleus tridentatus and Carcinoscorpius rotundicauda in the southern area to East Sea Island, referring to East Sea Island, Qishui, Xuwen, Suixi and Fangcheng, most of which were Tachypleus tridentatus, and found a great number of larvae of Tachypleus tridentatus including zooids with different sizes from 7cm bodily length to mature. In Minan we found not only big colonies of adult Carcinoscorpius rotundicauda , but also a great number of larvae of Carcinoscorpius rotundicauda with different body size from 7cm body length to maturity. All these show that the northern sea area of the South China Sea is the area where both Tachypleus tridentatus and Carcinoscorpius rotundicauda distribute and reproduce. On January 1st, 1998 at the town of Qishui in Leizhou, we found an adult male Horseshoe crab and majority of its eggs was immature, while the eggs with above 4mm diameters were only 0.87 percent but the eggs with below 1.0mm diameter was 58 percent(1 160 pills). It shows that Qishui is a place where Tachyplers tridentatus survive in the winter.     

植物（口山）酮类化合物的波谱特征

结合大量文献和实验工作 ,对植物 (主要是獐牙菜属 )口山酮类化合物的波谱特征进行总结和归纳。     

口泰含漱液对控制菌斑和牙龈炎的疗效分析

本研究采用双盲随机对照法观察口泰含液对牙龈炎及控制菌斑的疗效。结果显示：实验组的牙龈指数,龈沟出血指数及菌斑指数以在含漱５天后均有明显的改善,且与对照组的比较也有明显的差异。     

南方医科大学珠江医院肿瘤中心

南方医科大学附属珠江医院肿瘤中心(原第一军医大学全军肿瘤中心),为国家肿瘤学硕士、博士学位授权学科,肿瘤学博士后临床工作站。中心现有教     

用细菌清除近岸海域油污染的研究

用细菌清除近岸海域油污染的研究李永祺,黄健（青岛海洋大学海洋生命学院２６６００３）在１９９２年联合国环境与发展大会上通过的《二十一世纪议程》,建议有关生物技术应用于环境保护中,应开展＂通过使用生物降解材料减少废物量,从环境中消除污染物,例如偶然的石油泄漏＂的研究。（转引自＂中国环境报＂１９９２年７月１４日）。