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371.
Weibin Song Baobao Wang rew L Hauck Xiaomei Dong Jieping Li Jinsheng Lai 《植物学报(英文版)》2016,58(3):266-279
Maize(Zea mays) root system architecture(RSA)mediates the key functions of plant anchorage and acquisition of nutrients and water. In this study,a set of 204 recombinant inbred lines(RILs) was derived from the widely adapted Chinese hybrid ZD958(Zheng58 Chang7-2),genotyped by sequencing(GBS) and evaluated as seedlings for 24 RSA related traits divided into primary,seminal and total root classes. Signi ficant differences between the means of the parental phenotypes were detected for 18 traits,and extensive transgressive segregation in the RIL population was observed for all traits. Moderate to strong relationships among the traits were discovered. A total of 62 quantitative trait loci(QTL) were identi fied that individually explained from1.6% to 11.6%(total root dry weight/total seedling shoot dry weight) of the phenotypic variation. Eighteen,24 and 20 QTL were identi fied for primary,seminal and total root classes of traits,respectively. We found hotspots of 5,3,4 and 12 QTL in maize chromosome bins 2.06,3.02-03,9.02-04,and 9.05-06,respectively,implicating the presence of root gene clusters or pleiotropic effects. These results characterized the phenotypic variation and genetic architecture of seedling RSA in a population derived from a successful maize hybrid. 相似文献
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An individual behaviour-based model can predict shorebird mortality using routinely collected shellfishery data 总被引:3,自引:0,他引:3
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Life on the edge: the plankton and chemistry of Beaver Lake, an ultra-oligotrophic epishelf lake, Antarctica 总被引:2,自引:0,他引:2
Johanna Laybourn-Parry Wendy C. Quayle Tracey Henshaw rew Ruddell & Harvey J. Marchant 《Freshwater Biology》2001,46(9):1205-1217
1. Beaver Lake, a large epishelf lake in eastern Antarctica was sampled on two occasions during the austral summer of 2000. Two sites, one 1 km offshore and another 6 km offshore were sampled at intervals to depths of 40 and 110 m, respectively. 2. The lake is an end member of ultra‐oligotrophic lake systems with a very low carbon pool. Dissolved organic carbon concentrations ranged between 95 and 652 μg L–1. Nutrient levels were generally low with soluble reactive phosphorus ranging from undetectable to 8.4 μg L–1, ammonium ranged between 1.8 and 5.0 μg L–1, nitrate from undetectable to 161 μg L–1 and nitrite 1.1–5.3 μg L–1. 3. Chlorophyll a concentrations (0.39–4.38 μg L–1) showed an unusual distribution with the highest levels close to the lake bottom at the offshore site (110 m) where the phototrophic nanoflagellates (PNAN) displayed strong autofluorescence. 4. Bacterial concentrations were low, with a maximum of 7.60 × 107 L–1, as were the concentrations of heterotrophic nanoflagellates that exploit them. 5. Primary production ranged between 19.7 and 25.49 μg C L–1 day–1 and bacterial production from 0.32 to 1.15 μg C L–1 day–1. 6. In common with other continental Antarctic lakes, the system was dominated by a microbial plankton. However, a dwarf variety of the calanoid copepod, Boeckella poppei, occurred below 25 m at concentrations of 3–5 L–1. 7. The data suggest that primary production and bacterial production were not limited by nutrient availability, but by other factors, e.g. in the case of bacterial production by organic carbon concentrations and primary production by low temperatures. 相似文献
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Xue Gao Lei Wang Amar Kar Payal Ray Jane Y Wu Alvin P Joselin Andrew Bateman Alison M Goate 《蛋白质与细胞》2010,1(6):552
Progranulin (PGRN) has recently emerged as a key player in a subset of frontotemporal dementias (FTD). Numerous mutations in the progranulin gene have been identified in patients with familial or sporadic frontotemporal lobar degeneration (FTLD). In order to understand the molecular mechanisms by which PGRN deficiency leads to FTLD, we examined activity of PGRN in mouse cortical and hippocampal neurons and in human neuroblastoma SH-SY5Y cells. Treatment of mouse neurons with PGRN protein resulted in an increase in neurite outgrowth, supporting the role of PGRN as a neurotrophic factor. PGRN treatment stimulated phosphorylation of glycogen synthase kinase-3 beta (GSK-3β) in cultured neurons. Knockdown of PGRN in SH-SY5Y cells impaired retinoic acid induced differentiation and reduced the level of phosphorylated GSK-3β. PGRN knockdown cells were also more sensitized to staurosporine- induced apoptosis. These results reveal an important role of PGRN in neurite outgrowth and involvement of GSK-3β in mediating PGRN activity. Identification of GSK-3β activation as a downstream event for PGRN signaling provides a mechanistic explanation for PGRN activity in the nervous system. Our work also suggest that loss of axonal growth stimulation during neural injury repair or deficits in axonal repair may contribute to neuronal damage or axonal loss in FTLD associated with PGRN mutations. Finally, our study suggests that modulating GSK-3β or similar signaling events may provide therapeutic benefits for FTLD cases associated with PGRN mutations. 相似文献
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