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91.
It has been shown that intrauterine effect of ethanol causes alterations of protein phosphorylation, glycoprotein and lipid synthesis in rat brain in late ontogenesis. These alterations correlated with disordered learning and maintenance of the conditioned reflexes. 相似文献
92.
A rapid method for bacterial chemotaxis in a spatial gradient of chemoeffectors has been developed. The method is based on turbidimetric measurement of bacteria movement in a chemoeffector gradient created in a spectrophotometer cuvette. The method was verified onEscherichia coli mutants with known chemotactic properties. 相似文献
93.
He Li Wang Yu-Bo Bridges William C. He Zhulin Che S. Megan 《Statistics in biosciences》2023,15(1):114-140
Statistics in Biosciences - In observational studies, principal stratification is a well-established method in causal analysis to adjust the treatment effect estimation for post-treatment... 相似文献
94.
White rats were subjected to ethanol exposure during 5-20 days of pregnancy. 3H-muscimol binding with synaptosomal neocortex membranes yielded from two month age offsprings was studied. 3H-muscimol binding level for experimental animals was 27% more than for control ones. Possible ways of GABAergic system malformation are discussed. 相似文献
95.
Quod erat demonstrandum? The mystery of experimental validation of apparently erroneous computational analyses of protein sequences
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Lakshminarayan M Iyer L Aravind Peer Bork Kay Hofmann Arcady R Mushegian Igor B Zhulin Eugene V Koonin 《Genome biology》2001,2(12):research0051.1-research005111
Background
Computational predictions are critical for directing the experimental study of protein functions. Therefore it is paradoxical when an apparently erroneous computational prediction seems to be supported by experiment. 相似文献96.
V V Zhulin 《Biulleten' eksperimental'no? biologii i meditsiny》1988,105(5):558-561
Exposure to ethanol during pregnancy results in the alteration of (3H)-diazepam binding to synaptosomal neocortical membranes from the rat offspring. In male rats, 14 days of age, binding level diminished to 11%. In two-month-old control rats Scatchard plot was biphasic. It has been shown that prenatal exposure to ethanol leads to changes in the nature of binding in two-month-old experimental animals, as compared with the control ones. Possible relationship is discussed between the brain benzodiazepine system disorders and behaviour. 相似文献
97.
IB RODE PEDERSEN 《Nature: New biology》1971,234(47):112-114
IT has been proposed that lymphocytic choriomeningitis (LCM) virus and immunologically related viruses should be placed in a new taxonomic group, with LCM virus as the prototype virus1,2. They were called arenoviruses because they contain, as a unique feature, electron-dense, sand-like or ribo-some-like granules2. The LCM virus contains RNA and we have previously reported that this RNA can be separated into three components by density gradient centrifugation3. 相似文献
98.
V V Zhulin 《Biulleten' eksperimental'no? biologii i meditsiny》1988,106(9):317-319
Male rats, whose mothers were given ethanol during pregnancy, were injected inorganic P32 into lateral brain ventricles. Some animals during 1 hour before decapitation were subjected to stress. Phosphatidylethanolamine, phosphatidylcholine and phosphatidylserine were isolated from neocortex and hippocamp. Prenatal alcohol treatment led to 30% inorganic P32 incorporation increase into neocortex phosphatidylcholine. Stress was followed by phosphatidylcholine synthesis level decrease in neocortex by 13% and in hippocamp by 26%. Amplitude of phospholipid synthesis alterations increased after both prenatal alcohol treatment and stress. The results show that prenatal alcohol treatment results in essential disfunction of brain phospholipids synthesis. 相似文献
99.