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31.
Jeong LS Gunaga P Kim HO Tosh DK Lee HW Choe SA Moon HR Gao ZG Jacobson KA Chun MW 《Nucleosides, nucleotides & nucleic acids》2007,26(8-9):1011-1014
Stereoselective functionalization of the 1'-position of 4'-thionucleosides was achieved using a stereoselective S(N)2 reaction controlled by 5-membered ring coordination. 相似文献
32.
33.
I. Sivanesan Byoung Ryong Jeong 《In vitro cellular & developmental biology. Plant》2007,43(5):436-441
A method was developed to initiate multiple shoots from mature nodal explants of Sida cordifolia Linn. High frequency of regeneration was achieved on Murashige and Skoog (MS) medium supplemented with 2.0 mg l−1 6-benzylaminopurine, 0.5 mg l−1 α-naphthalene acidic acid, 1.0 mg l−1 adenine sulfate, and 10% (v/v) coconut milk. Multiple shoots were initiated within 21 d and the above media was capable of inducing the formation of more
than 20 shoots from each explant. Regenerated shoots were successfully rooted on half-strength MS medium supplemented with
2.0 mg l−1 indole-3-butyric acid and 3% (w/v) sucrose. Rooted plantlets were established in soil. The regenerated plantlets showed no morphological differences from the
parent material. This protocol could be useful for germplasm conservation, cultivation, and genetic improvement of S. cordifolia. 相似文献
34.
Moon HR Park AY Kim KR Chun MW Jeong LS 《Nucleosides, nucleotides & nucleic acids》2007,26(10-12):1653-1657
Novel L-bicyclocarba-d4T (1), an enantiomer of D-N-MCd4T has been enantiopurely synthesized as a potent anti-HIV agent starting from (R)-epichlorohydrin using tandem alkylation, chemoselective reduction of ester in the presence of lactone functional group, Grignard reaction, RCM reaction, and Mitsunobu reaction as key steps. L-N-MCd4T (1) was found to be very potent anti-HIV-1 (EC(50) = 6.76 microg/mL) agent with no cytotoxicity. 相似文献
35.
Jeong LS Lee JA Kim HO Tosh DK Moon HR Lee SJ Lee KM Sheen YY Chun MW 《Nucleosides, nucleotides & nucleic acids》2007,26(8-9):1021-1024
Novel 2'-C-methyl-cyclopropyl-fused carbocyclic nucleosides as potential anti-HCV agents were stereoselectively synthesized, utilizing regioselective cleavage of the isopropylidene group and cyclic sulfate chemistry as key steps. 相似文献
36.
Chun MW Lee HW Kim JH Kim HO Lee KM Pal S Moon HR Jeong LS 《Nucleosides, nucleotides & nucleic acids》2007,26(6-7):729-732
Homo-apioneplanocin A (1) as a potential inhibitor of S-adenosylhomocysteine hydrolase was synthesized from D-ribose, employing stereoselective hydroxymethylation, regioselective oxidation, and regio- and chemoselective hydroboration as key steps. 相似文献
37.
38.
Genome sequence of Leuconostoc argentinum KCTC 3773 总被引:1,自引:0,他引:1
Leuconostoc argentinum is one of the most prevalent lactic acid bacteria present during the manufacturing process of kimchi, the best-known traditional Korean dish. Here, we present the draft genome sequence of type strain KCTC 3773 of Leuconostoc argentinum (1,720,683 bp, with a G+C content of 42.9%), which consists of 98 large contigs (>100 bp in size). 相似文献
39.
Kim DS Sin Y Kim DW Paek J Kim RN Jung MY Park IS Kim A Kang A Park HS Choi SH Chang YH 《Journal of bacteriology》2012,194(11):3015-3016
The novel Sporolactobacillus vineae SL153(T) strain has excellent intestinal adherence and growth inhibitory effect on pathogenic microorganisms, including Vibrio genus microorganisms, and therefore can be effectively used for the prevention and treatment of disease caused by pathogenic microorganisms. Here, we first report the draft genome sequence of a novel species in the genus Sporolactobacillus. 相似文献
40.
Kim RN Kim DS Choi SH Yoon BH Kang A Nam SH Kim DW Kim JJ Ha JH Toyoda A Fujiyama A Kim A Kim MY Park KH Lee KS Park HS 《DNA research》2012,19(3):275-287
Although pioneering sequencing projects have shed light on the boxer and poodle genomes, a number of challenges need to be met before the sequencing and annotation of the dog genome can be considered complete. Here, we present the DNA sequence of the Jindo dog genome, sequenced to 45-fold average coverage using Illumina massively parallel sequencing technology. A comparison of the sequence to the reference boxer genome led to the identification of 4 675 437 single nucleotide polymorphisms (SNPs, including 3 346 058 novel SNPs), 71 642 indels and 8131 structural variations. Of these, 339 non-synonymous SNPs and 3 indels are located within coding sequences (CDS). In particular, 3 non-synonymous SNPs and a 26-bp deletion occur in the TCOF1 locus, implying that the difference observed in cranial facial morphology between Jindo and boxer dogs might be influenced by those variations. Through the annotation of the Jindo olfactory receptor gene family, we found 2 unique olfactory receptor genes and 236 olfactory receptor genes harbouring non-synonymous homozygous SNPs that are likely to affect smelling capability. In addition, we determined the DNA sequence of the Jindo dog mitochondrial genome and identified Jindo dog-specific mtDNA genotypes. This Jindo genome data upgrade our understanding of dog genomic architecture and will be a very valuable resource for investigating not only dog genetics and genomics but also human and dog disease genetics and comparative genomics. 相似文献