全文获取类型
收费全文 | 376篇 |
免费 | 39篇 |
国内免费 | 100篇 |
出版年
2023年 | 8篇 |
2022年 | 8篇 |
2021年 | 22篇 |
2020年 | 10篇 |
2019年 | 6篇 |
2018年 | 10篇 |
2017年 | 6篇 |
2016年 | 13篇 |
2015年 | 28篇 |
2014年 | 27篇 |
2013年 | 27篇 |
2012年 | 46篇 |
2011年 | 43篇 |
2010年 | 29篇 |
2009年 | 36篇 |
2008年 | 39篇 |
2007年 | 30篇 |
2006年 | 22篇 |
2005年 | 17篇 |
2004年 | 17篇 |
2003年 | 20篇 |
2002年 | 9篇 |
2001年 | 4篇 |
2000年 | 7篇 |
1999年 | 7篇 |
1998年 | 7篇 |
1997年 | 4篇 |
1996年 | 2篇 |
1995年 | 3篇 |
1994年 | 4篇 |
1991年 | 1篇 |
1988年 | 1篇 |
1987年 | 1篇 |
1986年 | 1篇 |
排序方式: 共有515条查询结果,搜索用时 15 毫秒
511.
512.
Jian Hou En-Min Li Jin-Hui Shen Qing-Zhao Zhi-Yong Wu Xiu-E Xu Jian-Yi Wu Qiao-Huang Jian Shen Ming-Zhou Guo Li-Yan Xu 《The journal of histochemistry and cytochemistry》2011,59(7):711-718
The aim of this study was to evaluate HDPR1 expression in esophageal squamous cell carcinoma (ESCC) and the relationship between HDPR1 and beta-catenin by immunohistochemical analysis. The clinical relevance of these proteins was also analyzed. Immunohistochemistry was performed on paraffin-embedded tissue specimens from 184 ESCC patients to detect the expression of HDPR1 and beta-catenin. The correlation between the results of immunoexpression and the clinicopathologic features was processed statistically. Increased cytoplasmic and nuclear HDPR1 expression was noted in 100 (54.3%) and 131 (71.2%) of 184 specimens, respectively. Statistical analysis showed significant associations of cytoplasmic HDPR1 with regional lymph node metastasis (p = 0.021) and P-stage (p = 0.004). The increased nuclear staining was only correlated with P-stage (p = 0.047). Significant associations of coexpression of cytoplasmic and nuclear HDPR1 with regional lymph node metastasis (p = 0.015) or P-stage (p = 0.002) were observed. Enhanced cytoplasmic expression of HDPR1 was positively correlated with increased cytoplasmic but not reduced membranous beta-catenin expression (r = 0.239, p = 0.027 and r = 0.126, p = 0.089, respectively). These finding suggested that cytoplasmic HDPR1 protein expression was associated with tumor malignant progression via beta-catenin accumulation. It implicated that cytoplasmic HDPR1 expression may serve as a potential predictive factor for lymph node metastasis and tumor development in ESCC. 相似文献
513.
Liao Zhi-Yong Scheepens J. F. Li Qiao-Ming Wang Wei-Bin Feng Yu-Long Zheng Yu-Long 《Oecologia》2020,192(1):105-118
Oecologia - Multiple mechanisms may act synergistically to promote success of invasive plants. Here, we tested the roles of three non-mutually exclusive mechanisms—founder effects,... 相似文献
514.
515.