Affinity sorbent based on tryptophyl-threonyl-tyrosine for binding of the immunoglobulins G: Sorption characteristics and aspects of practical application

Chromatographic material based on tryptophil-threonyl-tyrosine and efficiently binding human, sheep, goat, and bovine immunoglobulin G was obtained. High selectivity of the sorbent for extraction of immunoglobulins from blood plasma has been demonstrated. Effective sorption capacity is 15–25 mg of immunoglobulin G per 1 ml of the matrix. Optimization of the method of triptophyl-threonyl-tyrosine covalent binding to the polysaccharide matrix allowed the achievement of high sorbent stability in conditions of use and storage. This sorbent may be used in medicine and biotechnology.     

Analysis of the Genetic Demographic Structure of Rural Populations Neighboring the Semipalatinsk Nuclear Test Site

Rural populations neighboring the Semipalatinsk nuclear test site were used as a model to develop and test an integrated population-genetic approach to analysis of the medical genetic situation and environmental conditions in the areas studied. The contributions of individual factors of population dynamics into the formation of the genetic load were also assessed. The informative values of some genetic markers were estimated. Based on these estimates, a mathematical model was constructed that makes it possible to calculate numerical scores for analysis of the genetic loads in populations differing in environmental exposure.     

“Antioxidant enzymes and physiological characteristics in two jerusalem artichoke cultivars under salt stress”

Russian Journal of Plant Physiology -