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11.
We studied in the rat the effects of the drug etretinate (Tigason), given at three doses 3, 10, and 30 mg/kg body wt for 1 mo, on the concentrations of Na, K, Ca, Mg, Fe, S, P, Cu, and Zn in the plasma, brain, thymus, heart, liver, lung, kidney, testicle, muscle, and bone. The elements were simultaneously determined in tissues after nitric acid dissolution by inductively coupled plasma emission spectrometry using a JY 48 instrument. At the dose of 3 mg/kg, etretinate did not induce any statistically significant modifications of the element distribution. At the dose of 10 mg/kg, the main observed modifications were in plasma an increase of copper (+38%) and a decrease of zinc (-25%). At the highest dose of 30 mg/kg, some variations of the concentrations of elements in tissues were observed. But, on no account did retinoids induce an alteration of the mineral composition of bone, despite obvious macroscopic bone alterations. 相似文献
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Prevalence of the 281 (Gly→Glu) mutation in hepatoerythropoietic porphyria and porphyria cutanea tarda 总被引:4,自引:0,他引:4
Hubert de Verneuil Joanna Hansen Christiane Picat Bernard Grandchamp James Kushner Andrew Roberts George Elder Yves Nordmann 《Human genetics》1988,78(1):101-102
Summary The prevalence of the 281 (GlyGlu) mutation in hepatoerythropoietic porphyria (HEP) was investigated by the use of hybridization with a synthetic oligonucleotide probe. The mutation was found in HEP-affected members of two unrelated families from Spain, but was absent in two other patients from Italy and Portugal who also had HEP. Moreover, this mutation was not detected in 13 unrelated cases of familial (type II) porphyria cutanea tarda. 相似文献
14.
Yves Roisin 《Zoomorphology》1988,107(6):339-347
Summary The existence of a worker caste in Prorhinotermes inopinatus was determined with the help of biometrical analyses and morphological observations. No dichotomy between alate and worker lines was detected among the young larval instars. Mandible sclerotization and wear show that the larvae become active by the fourth instar in mature colonies, and by the third in incipient ones. Prothoracic finger-shaped expansions characterize the most dependent larval instars. The antennal structure is the best feature for distinguishing late instars. The developmental schema is very flexible: the late larvae of stages 5 to 8 (at least) can give rise to wing-padded nymphs, to the next larval instar, to presoldiers, or most likely to neotenic reproductives as well; the wing-padded individuals (nymphs) normally moult direct to alates, but they can also undergo a regression of their wing pads and revert to worker-like individuals or differentiate into soldiers or neotenics. Slight variations in alate size and antennal morphology result from their origin in different larval instars. Whole-colony censuses revealed that the major part of the colony's work force is composed of pseudergates, i.e. late larvae that do not follow the most direct pathway to the alate. The pseudergates of Prohinotermes do not constitute a distinct worker caste irreversibly diverted from the alate developmental pathway. For this reason the caste system of Prorhinotermes is analogous to that of the Kalotermitidae and Termopsidae and much more primitive than those of the other Rhinotermitidae so far studied, Reticulitermes, Schedorhinotermes and Coptotermes.Contribution No. 139 from King Léopold III Biological Station, Laing Island, Papua New GuineaSenior research assistant of the National Fund for Scientific Research, Belgium 相似文献
15.
Salas-Prato Milagros Tanguay Jean-Francois Lefebvre Yves Wojciechowicz Don Liem H. Heng Barnes David W. Ouellette Ginette Muller-Eberhard Ursula 《In vitro cellular & developmental biology. Plant》1988,24(5):470-470
In Vitro Cellular &; Developmental Biology - Plant - 相似文献
16.
Forest succession following fire in a forest mosaic of northwestern Quebec has been studied in order to: (1) describe the successional pathways using communities of different ages and (2) evaluate convergence of successional pathways and possible effect of fire suppression on the establishment of steady-state communities. As a first step, ordination and classification techniques were used in order to remove changes in forest composition which are related to abiotic conditions. Then, ordinations based on tree diameter distributions were used to study shifts in species composition in relation to time since the last fire.Even under similar abiotic conditions, successional pathways are numerous. However, regardless of forest composition after fire, most stands show convergence toward dominance of Thuja occidentalis and Picea mariana on xeric sites and dominance of Abies balsamea and Thuja occidentalis on more mesic sites. Stable communities of >300 yr occur on xeric sites while on mesic sites directional succession still occurs after 224 yr. Nearly all species involved in succession are present in the first 50 yr following fire. Only Abies balsamea and Thuja occidentalis increase significantly in frequency during succession. Following initial establishment, successional processes can generally be explained by species longevity and shade tolerance. Early successional species may be abundant in the canopy for more than 200 yr while the rapid decrease of Picea glauca, a late successional species could be related to spruce budworm outbreaks. Considering the short fire rotation observed (about 150 yr), a steady-state forest is unlikely to occur under natural conditions, though it may be possible if fire is controlled. 相似文献
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Basic differences between the 13C and the 14C techniques ofmeasuring carbon uptake by phytoplankton exist at the levelof the isotopic analysis. With the first method, a ratio ofisotopic abundances is measured on the sample, whereas an absoluteamount of isotope is estimated with the second method. If acarbon source other than the labeled one is utilized by thephytoplankton during incubation, the stable isotope method maybe biased. Specific uptake values will be underestimated bythis effect. It is, however, possible to obtain unbiased estimatesof the 13C-labeled carbon uptake by using an equation containinga term describing the final particulate carbon concentration.Only under this condition will carbon uptake rates derived from13C isotope data be always compatible with the 13C method ofmeasuring primary production
*This paper is the result of a study made at the Group for AquaticPrimary Productivity (GAP), Second International Workshop heldat the National Oceanographic Institute, Haifa, Israel in AprilMay1984. 相似文献
19.
Dr. Guy D. Fauque Yves M. Berlier Melvin H. Czechowski Bernard Dimon Paul A. Lespinat Jean LeGall 《Journal of industrial microbiology & biotechnology》1987,2(1):15-23
Summary Hydrogenases are among the main enzymes involved in bacterial anaerobic corrosion of metals. The study of their mode of action is important for a full comprehension of this phenomenon. The three types ofDesulfovibrio hydrogenases [(Fe), (NiFe), (NiFeSe)] present different patterns in the pH dependence of their activity. The periplasmic enzyme fromDesulfovibrio salexigens and the cytoplasmic enzyme fromDesulfovibrio baculatus both have pH optima at 7.5 for H2 uptake and 4.0 for H2 evolution and H+–D2 exchange reaction (measured by membrane-inlet mass-spectrometry). The H2 to HD ratio at pH above 5.0 is higher than 1.0. The periplasmic hydrogenase fromD. gigas presents the same pH optimum (8.0) for the H+–D2 exchange as for H2 consumption. In contrast, the enzyme fromD. vulgaris has the highest activity in H2 production and in the exchange at pH 5.0. Both hydrogenases have a H2-to-HD ratio below 1.0. 相似文献
20.
Dr. Paul A. Lespinat Yves M. Berlier Guy D. Fauque Rene Toci Gerard Denariaz Jean LeGall 《Journal of industrial microbiology & biotechnology》1987,1(6):383-388
Summary Hydrogenase and nitrogenase activities of sulfate-reducing bacteria allow their adaptation to different nutritional habits even under adverse conditions. These exceptional capabilities of adaptation are important factors in the understanding of their predominant role in problems related to anaerobic metal corrosion. Although the D2–H+ exchange reaction indicated thatDesulfovibrio desulfuricans strain Berre-Sol andDesulfovibrio gigas hydrogenases were reversible, the predominant activity in vivo was hydrogen uptake. Hydrogen production was restricted to some particular conditions such as sulfate or nitrogen starvation. Under diazotrophic conditions, a transient hydrogen evolution was followed by uptake when dinitrogen was effectively fixed. In contrast, hydrogen evolution proceeded when acetylene was substituted as the nitrogenase substrate. Hydrogen can thus serve as an electron donor in sulfate reduction and nitrogen metabolism. 相似文献