Ca2+-dependent K+ permeability of heart sarcolemmal vesicles. Modulation by cAMP-dependent protein kinase activity and by calmodulin

The Ca2+-dependent K+ permeability of heart sarcolemma vesicles was measured by following the transmembrane movement of the charge compensating tetraphenylborate anion. The increase in vesicles permeability induced by Ca2+ is lost when membrane proteins are dephosphorylated by an endogenous protein phosphatase and is restored by a phosphorylation process catalysed by a cAMP-dependent protein kinase. The calmodulin antagonist R 24571 lowers the Ca2+-dependent K+ permeability by decreasing the Ca2+ affinity of the K+ transporting system.     

Baseline and sodium arsenite-induced sister chromatid exchanges in cultured lymphocytes from patients with Blackfoot disease and healthy persons

Summary A significantly higher frequency of baseline sister chromatid exchange (SCE) was found in the cultured lymphocytes of 13 Blackfoot disease patients (BFP) in comparison with that of healthy persons (HP). Twelve of these BFP consumed well water containing a high concentration of arsenic for 15 years or longer and had switched to drinking tap water 12 years before the time of this study. Sodium arsenite was found to be effective in increasing the SCE frequency and delaying the cell growth of the lymphocytes from both BFP and HP. However, the SCE increment induced by sodium arsenite as well as the progression of the cell divisions in the cultured lymphocytes showed no significant difference between BFP and HP.     

Histochemical localization of zinc in the feline tapetum

Summary High resolution electron microscopy of ultrathin sections confirms the presence of a membrane surrounding the tapetal rods in the cat. Cats depleted of taurine exhibit disruption and disorganization of this membrane, probably the first stage of more severe tapetal degeneration. Histochemical localization of zinc shows it to be present on the periphery of the tapetal rods. The amount of zinc present on the periphery of the tapetal rods of taurine depleted cats was greatly reduced. Taurine in feline tapetum, confirmed by autoradiography and direct measurement, was also greatly reduced in taurine-depleted cats. We conclude that both taurine and zinc are localized on the periphery of the tapetal rods and that they contribute to the stability of the membrane. We have also confirmed earlier reports that the cat tapetal rods contain riboflavin and no detectable cysteine.Presented in part at the International Symposium Taurine-Questions and Answers Mexico City, November 16–19, 1980     

晋西北黄河岸边新发现的旧石器地点

在山西省河曲县河会村附近发现一个旧石器地点,从中发现石制品十多件,其地质时代为中更新世晚期。     

泥炭藓群落的光谱特征及遥感识别研究

以中位泥炭藓（Sphagnum magellanicum Brid.）为研究对象,分别从实测冠层光谱和遥感传感器模拟光谱层面分析其群落的光谱特征。研究结果显示,中位泥炭藓与北方针叶林光谱差异明显,最佳光谱识别区间为740~1140 nm和1230~1412 nm。在可见光波段上,中位泥炭藓与云杉（Picea engelmannii Parry ex Engelmann）和黑松（Pinus contorta Douglas ex Loudon）的绿峰位置有所差异。水竹（Phyllostachys heteroclada Oliver）和中位泥炭藓的光谱识别特征波段集中在可见光-近红外波段,分别为400~550、560~696、1025~1143 nm。中位泥炭藓与北方针叶林以及水竹的特征光谱区间存在细微差异,且与水竹在可见光波段有较好的可分性,因此不同纬度带上中位泥炭藓群落的特征谱宽有所差异。红外波段是中位泥炭藓识别的最佳光谱区间。在多光谱遥感水平上,中位泥炭藓识别效果较好,传感器的识别能力依次为：MSI > ALI > OLI > ASTER。在2个中位泥炭藓群落的光谱特征分析中,导数、对数、包络线去除法的光谱降维能力有所差异,其中包络线去除法效果最好。     

长白山区瓦蛛属三新纪录种（蜘蛛目：皿蛛科：微蛛亚科）

本文记述了我国瓦蛛属三新纪录种,即突褶瓦蛛Walckenaeria sounkyoensis、钉角瓦蛛Walckenaeria claviornis、霍氏瓦蛛Walckenaeria holmi。本文量度单位:mm。标本保存在长春市白求恩医科大学生物教研室。     

山鸡椒根部精油化学成分的研究

采用水蒸气蒸馏、气相层析、标准品加入和归一法等综合技术鉴定出山鸡椒根部精油含α-蒎烯、柠檬烯、1.8-桉叶素、对聚伞花素、香草醛、甲基庚烯酮、异胡薄荷醇、香叶醇甲酸酯、α-松油醇、香草醇,柠檬醛a,b、香叶醇、丁香酚十三个成分。     

溶液流动对等电溶菌酶晶体生长的影响

本文对等温自由生长和强制性溶液生长的等电溶菌酶的晶体形态进行了研究,发现这些形态变化与溶液相的流动密切相关,指出生物晶体生长停止是由于生长晶体周围的溶质贫乏造成的;通过某些手段减薄或消除这一溶质贫乏区,就可以保证晶体的持续生长。本文的研究对改善大尺寸晶体的生长提供了一条途径。     

原发性高血压患者红细胞中存在抗高血压因子

本研究利用热处理和Sephadex G-150凝胶过滤层析等方法,从原发性高血压病患者(EHS)红细胞中部分纯化了抗高血压因子(AHF)。AHF具有热稳定性,分子量大于6kDa;能明显降低卒中易感型自发性高血压大鼠(SHR_(sp))血压,腹腔一次注入AHF(1.6mg/kg)30min后,SHR_(sp)收缩压从原来的27.6±0.7kPa降低到21.4±0.8kPa(p<0.001),4h后收缩压恢复至原水平。AHF能显著抑制自发性高血压大鼠(SHR)和肾性高血压大鼠(RHR)主动脉(A)及肠系膜动脉(MA)血管平滑肌(VSM)Ca~(2 )内流。且对MA Ca~(2 )内流的抑制作用强于A。以上结果表明:EHS红细胞中存在AHF,能显著降低高血压大鼠血压,其降压机制可能与其抑制VSM特别是小动脉VSM Ca~(2 )内流有关。