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831.
832.
Zhang Xiaonan Lu Yufang Yang Ting Kronzucker Herbert J. Shi Weiming 《Plant and Soil》2019,441(1-2):253-259
Plant and Soil - Depending on the availability and stoichiometry of nutrients in soil, microbes and plants can compete for the same resources. In this study we aimed to test how microbial nutrient... 相似文献
833.
834.
Xu Chen Lei Shi Yuqin Chen Lu Zhu Dasheng Zhang Shi Xiao Asaph Aharoni Jianxin Shi Jie Xu 《Plant, cell & environment》2019,42(4):1190-1204
Sepals play important roles in protecting inner floral organs from various stresses and in guaranteeing timely flower opening. However, the exact role of sepals in coordinating interior and exterior signals remains elusive. In this study, we functionally characterized a heat shock protein gene, Arabidopsis HSP70‐16, in flower opening and mild heat stress response, using combined genetics with anatomic, physiological, chemical, and molecular analyses. We showed that HSP70‐16 is required for flower opening and mild heat response. Mutation of HSP70‐16 led to a significant reduction in seed setting rate under 22°C, which was more severe at 27°C. Mutation of HSP70‐16 also caused postgenital fusion at overlapping tips of two lateral sepals, leading to failed flower opening, abnormal floral organ formation, and impaired fertilization and seed setting. Chemical and anatomic analyses confirmed specific chemical and morphological changes of cuticle property in mutant lateral sepals, and qRT‐PCR data indicated that expression levels of different sets of cuticle regulatory and biosynthetic genes were altered in mutants grown at both 22°C and 27°C temperatures. This study provides a link between thermal and developmental perception signals and expands the understanding of the roles of sepal in plant development and heat response. 相似文献
835.
836.
Liu Shuai Li Su Fan Xiao-Yang Yuan Guo-Di Hu Tao Shi Xian-Meng Huang Jun-Biao Pu Xiao-Yan Wu Chuan-Sheng 《Photosynthesis research》2019,141(2):245-257
Photosynthesis Research - Chlorophyll content in lichens is routinely used as an accurate indicator of lichen vigor, interspecific differences, and the effect of site-related environmental... 相似文献
837.
Dan Liu Xiaoxi Li Xintian Chen Yu Sun Anqun Tang Zhongwei Li Junnian Zheng Ming Shi 《生物化学与生物物理学报:癌评论》2019,1871(1):20-28
The treatment of cancer has made great progress. However, drug resistance remains problematic. Multiple physiologic processes of tumor development can be dominated by central and sympathetic nervous systems. The interactions between the nervous system, immune system, and tumor occur consistently and dynamically. Recent evidence suggests that nerves and neural signals are intimately involved in the development of resistance to cancer therapies. In this review, we will provide an overview of the recent progress in this rapidly growing area and discuss the potential new strategies for targeting the neural signaling pathway to improve the effectiveness of chemotherapies, targeted therapies, and immunotherapies. 相似文献
838.
Long Huiping Zhong Gang Wang Chengzhi Zhang Jian Zhang Yueling Luo Jinglian Shi Shengliang 《Neurochemical research》2019,44(8):1830-1839
Neurochemical Research - The pathogenesis of late-onset Alzheimer's disease (LOAD) mainly involves abnormal accumulation of extracellular β-amyloid (Aβ) and the consequent neurotoxic... 相似文献
839.
Pseudomonas amygdali pv. lachrymans is currently of important plant pathogenic bacteria that causes cucumber angular leaf spot worldwide. The pathogen has been studied for its roles in pathogenicity and plant inheritance resistance. To further delineate traits critical to virulence, invasion and survival in the phyllosphere, we reported the first complete genome of P. amygdali pv. lachrymans NM002. Analysis of the whole genome in comparison with three closely-related representative pathovars of P. syringae identified the conservation of virulence genes, including flagella and chemotaxis, quorum-sensing systems, two-component systems, and lipopolysaccharide and antiphagocytosis. It also revealed differences of invasion determinants, such as type III effectors, phytotoxin (coronatine, syringomycin and phaseolotoxin) and cell wall-degrading enzyme, which may contribute to infectivity. The aim of this study was to derive genomic information that would reveal the probable molecular mechanisms underlying the virulence, infectivity and provide a better understanding of the pathogenesis of the P. syringae pathovars. 相似文献
840.
Junyu Lai Manqing Ge Sikui Shen Lu Yang Tao Jin Dehong Cao Hang Xu Xiaonan Zheng Shi Qiu Kunjie Wang Qiang Wei Hong Li Jianzhong Ai 《生物化学与生物物理学报:疾病的分子基础》2019,1865(9):2403-2410
Chronic cystitis is characterized by the hyperplasia and fibrosis of the bladder wall as well as attenuated compliance of the bladder. To further unravel its underlying molecular mechanism, the role of NFκB-JMJD3 signaling pathway in cystitis induced bladder fibrosis was investigated. Jmjd3 and Col1/3 expression was detected in a cystitis mouse model that was developed by intraperitoneal injection of cyclophosphamide (CYP). Human bladder smooth muscle cells (hBSMCs) were stimulated in vitro with lipopolysaccharide (LPS), and the cell proliferation and collagen accumulation were detected using EdU, CCK8, flow cytometry, qPCR, western blotting and immunofluorescence assays. Furthermore, the effects of NFκB and JMJD3 on cell proliferation and collagen accumulation were investigated using its selective antagonists, JSH23 and GSK-J4, respectively. CYP induced cystitis significantly increased Jmjd3, Col1 and Col3 expression in the bladder muscle cells. Furthermore, LPS stimulation markedly activated NFκB signaling and elevated JMJD3 expression in hBSMCs, and the activation of NFκB-JMJD3 signaling significantly promoted cell proliferation and collagen accumulation by upregulating CCND1 and COL1/3 expression, respectively. Our study reveals the critical role of NFκB-JMJD3 signaling in cystitis induced bladder reconstruction by regulating hBSMC proliferation and extracellular matrix (ECM) deposition, and these findings provide an avenue for effective treatment of patients with cystitis. 相似文献