全文获取类型
收费全文 | 431316篇 |
免费 | 50073篇 |
国内免费 | 2386篇 |
出版年
2018年 | 4305篇 |
2017年 | 4002篇 |
2016年 | 5483篇 |
2015年 | 7394篇 |
2014年 | 8866篇 |
2013年 | 11986篇 |
2012年 | 13545篇 |
2011年 | 13541篇 |
2010年 | 9058篇 |
2009年 | 8198篇 |
2008年 | 11332篇 |
2007年 | 11711篇 |
2006年 | 10945篇 |
2005年 | 10432篇 |
2004年 | 10342篇 |
2003年 | 10032篇 |
2002年 | 9911篇 |
2001年 | 22707篇 |
2000年 | 22680篇 |
1999年 | 17865篇 |
1998年 | 5552篇 |
1997年 | 5793篇 |
1996年 | 5426篇 |
1995年 | 5126篇 |
1994年 | 5024篇 |
1993年 | 4843篇 |
1992年 | 14131篇 |
1991年 | 13471篇 |
1990年 | 12862篇 |
1989年 | 12642篇 |
1988年 | 11688篇 |
1987年 | 10804篇 |
1986年 | 9767篇 |
1985年 | 9781篇 |
1984年 | 7876篇 |
1983年 | 6908篇 |
1982年 | 5312篇 |
1981年 | 4591篇 |
1980年 | 4344篇 |
1979年 | 7709篇 |
1978年 | 5789篇 |
1977年 | 5376篇 |
1976年 | 4911篇 |
1975年 | 5362篇 |
1974年 | 5737篇 |
1973年 | 5802篇 |
1972年 | 5321篇 |
1971年 | 4957篇 |
1970年 | 4205篇 |
1969年 | 4036篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
131.
S. Dubrou J. Konjek E. Macheras B. Welté L. Guidicelli E. Chignon M. Joyeux J. L. Gaillard B. Heym T. Tully G. Sapriel 《Applied and environmental microbiology》2013,79(18):5498-5508
Nonpigmented and late-pigmenting rapidly growing mycobacteria (RGM) have been reported to commonly colonize water production and distribution systems. However, there is little information about the nature and distribution of RGM species within the different parts of such complex networks or about their clustering into specific RGM species communities. We conducted a large-scale survey between 2007 and 2009 in the Parisian urban tap water production and distribution system. We analyzed 1,418 water samples from 36 sites, covering all production units, water storage tanks, and distribution units; RGM isolates were identified by using rpoB gene sequencing. We detected 18 RGM species and putative new species, with most isolates being Mycobacterium chelonae and Mycobacterium llatzerense. Using hierarchical clustering and principal-component analysis, we found that RGM were organized into various communities correlating with water origin (groundwater or surface water) and location within the distribution network. Water treatment plants were more specifically associated with species of the Mycobacterium septicum group. On average, M. chelonae dominated network sites fed by surface water, and M. llatzerense dominated those fed by groundwater. Overall, the M. chelonae prevalence index increased along the distribution network and was associated with a correlative decrease in the prevalence index of M. llatzerense, suggesting competitive or niche exclusion between these two dominant species. Our data describe the great diversity and complexity of RGM species living in the interconnected environments that constitute the water production and distribution system of a large city and highlight the prevalence index of the potentially pathogenic species M. chelonae in the distribution network. 相似文献
132.
The fine structure of meiotic chromosome pairing in natural and artificial Lilium polyploids 总被引:1,自引:0,他引:1
P B Moens 《Journal of cell science》1970,7(1):55-63
133.
134.
135.
136.
The ultrastructure of the interstitial cells of Cajal (ICC) in the oesophagus of the monkey resembled that described in the oesophagus of other mammalian species but differed in their paucity and almost lack of smooth endoplasmic reticulum, caveolae and filaments. The plasmalemma of the ICC was in close contact (20- to 30-nm gaps) with that of smooth muscle cells. This may occasionally take the form of a desmosome, but gap junctions have not been observed. Vesiculated axon profiles, containing large granular or agranular vesicles were in close contact (20- to 30-nm gaps) with the plasmalemma of ICC. In a few vesiculated profiles a presynaptic density could be recognized. The intercalation of the ICC between the vesiculated axon profiles and the smooth muscle cells suggest a role in oesophageal motility. Between 3 and 21 days following bilateral vagotomy some ICC showed regressive changes such as increased electron density and shrinkage of the cytoplasm, crowding of the organelles and dissolution of the nuclear chromatin material. Axon profiles in the vicinity of the affected ICC contained glycogen granules suggesting injury. In late stages, the number of ICC and smooth muscle contacts was reduced. The results suggest that the vagus nerves exert a trophic influence on the ICC and that the intercellular relationships between ICC and smooth muscle cells possess a degree of plasticity. It is tentatively suggested that these vagal effects may be mediated via the oesophageal myenteric ganglia. 相似文献
137.
Six hundred foramina transversaria (FT) of the axis vertebrae of 4 population groups were examined for the presence of erosion of the lateral articular mass. Of these, 127 (21%) and 72 (12%) presented with moderate and marked erosion, respectively. Evidence is presented incriminating the tortuosity of the vertebral artery as well as congenital factors in the etiology of the erosion of the FT. Attention is drawn to the possible correlation between angulation of the transverse process of the axis and erosion of the FT. 相似文献
138.
Ultrastructure of the epithelial cells of the ventral prostate from the hopping mouse Notomys alexis
The large ventral prostate of the hopping mouse has abundant secretory units whose epithelial cells vary in height and which often have nuclei in the apical region of the cell. TEM observations indicated two epithelial cell types in which some unusual features occurred. Type A cells had granular endoplasmetic reticulum (GER) whose membranes often formed intracytoplasmic confronting cisternae. Type B cells had more fragmented and vesiculated GER with sparse ribosomes and less frequently also intracytoplasmic confronting confronting cisternae. In the latter cells, two types of granules were found, one of which was derived from the Golgi and the other possibly directly from the GER. Type A cells only had one type of granule present. A highly convoluted membrane was also found at the basal region in many of the cells. The significance of these unusual ultrastructural features has yet to be ascertained. 相似文献
139.
Two internal herinias of the intestines were found in adult males. One was a large translucent avascular membranous sac contining the small intestine from the duodenojejunal flexure to a point 6 in. proximal to the ileocaecal junction. The other was a peritoneal sac enclosing the small intestine, appendix, caecum and 6 in. of the ascending colon. The mesenteric and colic vessels were normal. Both hernias conformed to PAPEZ's concept of the so-called paraduodenal hernia that the hernial sac is derived from the umbilical coelom. The authors suggest that most of the so-called paraduodenal hernias are derived from the embryonic umbilical peritoneal diverticulum rather than from the peritoneal recesses or mesentery of the colon. 相似文献
140.