全文获取类型
收费全文 | 48234篇 |
免费 | 3699篇 |
国内免费 | 3466篇 |
出版年
2024年 | 121篇 |
2023年 | 577篇 |
2022年 | 1379篇 |
2021年 | 2228篇 |
2020年 | 1523篇 |
2019年 | 1925篇 |
2018年 | 2052篇 |
2017年 | 1677篇 |
2016年 | 2176篇 |
2015年 | 2510篇 |
2014年 | 3222篇 |
2013年 | 3482篇 |
2012年 | 3967篇 |
2011年 | 3713篇 |
2010年 | 2622篇 |
2009年 | 2302篇 |
2008年 | 2637篇 |
2007年 | 2368篇 |
2006年 | 2071篇 |
2005年 | 1704篇 |
2004年 | 1597篇 |
2003年 | 1505篇 |
2002年 | 1231篇 |
2001年 | 1001篇 |
2000年 | 839篇 |
1999年 | 614篇 |
1998年 | 384篇 |
1997年 | 318篇 |
1996年 | 308篇 |
1995年 | 319篇 |
1994年 | 291篇 |
1993年 | 225篇 |
1992年 | 290篇 |
1991年 | 259篇 |
1990年 | 208篇 |
1989年 | 192篇 |
1988年 | 129篇 |
1987年 | 175篇 |
1986年 | 145篇 |
1985年 | 128篇 |
1984年 | 101篇 |
1983年 | 95篇 |
1982年 | 82篇 |
1981年 | 78篇 |
1980年 | 52篇 |
1979年 | 62篇 |
1978年 | 66篇 |
1976年 | 51篇 |
1973年 | 63篇 |
1972年 | 52篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
21.
Naumova E. V. Vladimirov Yu. A. Beloussov L. V. Tuchin V. V. Volodyaev I. V. 《Biophysics》2021,66(5):764-778
Biophysics - This review is devoted to the methods for studying the ultraweak luminescence of biological objects; in addition to modern methods aimed at studies in the visible, near-infrared, and... 相似文献
22.
Yunfan Sun Liang Wu Yu Zhong Kaiqian Zhou Yong Hou Zifei Wang Zefan Zhang Jiarui Xie Chunqing Wang Dandan Chen Yaling Huang Xiaochan Wei Yinghong Shi Zhikun Zhao Yuehua Li Ziwei Guo Qichao Yu Liqin Xu Jia Fan 《Cell》2021,184(2):404-421.e16
- Download : Download high-res image (233KB)
- Download : Download full-size image
23.
E. P. Isakova Yu. I. Deryabina N. N. Gessler T. A. Belozerskaya Ya. M. Rabinovich 《Applied Biochemistry and Microbiology》2010,46(3):318-323
Cell respiratory activity of protoplasts obtained from the wild type of Neurospora crassa and photoreceptor complex WCC—white collar 1 (wc-1) and white collar 2 (wc-2)—mutants of Neurospora crassa strains was investigated. Respiration inhibition by KCN in the presence of 25 mM succinate was similar in all strains and
did not exceed 83–85% against control. The significant induction of KCN-resistant respiratory pathway occurred under 1% glucose
oxidation in wc-1 and wc-2 mutants if compared with the wild type strains. The inhibitors of the main (cytochrome) pathway of electron transfer in mitochondria—1
mM KCN and antimycin A (4 μg/ml)—blocked the respiration rate of the protoplasts from N. crassa wild type by 75%, while the cell respiration of wc-1 and wc-2 strains was suppressed by approximately 50%. The specific inhibitor of alternative oxidase—10 mM salicylhydroxamic acid (SHAM)—in
combination with the blockers of mitochondrial electron transfer chain caused the total suppression of respiratory activity
of protoplasts in all studied strains. It is supposed that an increase of KCN-resistance in WCC mutants under glucose oxidation
is connected with alternative oxidase activation as the result of failure in reception and signal transduction of active oxygen
species. 相似文献
24.
The discrimination of the angular velocity of ventrodorsal and dorsoventral movement of an acoustic image was studied in nine test subjects. The experiments were performed using an apparent movement produced by consecutive activation of loudspeakers located along an arc in the vertical plane. The differential thresholds were measured by the minimum increment method. As the velocity of an acoustic image movement in opposite directions increased, the values of its mean absolute differential thresholds increased monotonically. Regression lines plotted by linear approximation of these values did not differ significantly. 相似文献
25.
L. G. Akhmetzyanova A. A. Saveliev S. Yu. Selivanovskaya 《Contemporary Problems of Ecology》2012,5(6):554-558
This paper presents an algorithm for determining the content of oil products in remediated soil that is safe for plants and microorganisms. The algorithm includes laboratory modeling of the remediation of soil samples that contain different amounts of soil products, determination of the biological parameters that provide the integral characterization of the soil state in these samples, and analysis of the results on the basis of odds-ratio statistics, which allows one to determine the content of oil products, starting from which the state of an oil-contaminated soil has no significant difference from a control soil. 相似文献
26.
Ai‐Xin Song Chen‐Jie Zhou Xiao Guan Kong‐Hung Sze Hong‐Yu Hu 《Protein science : a publication of the Protein Society》2010,19(5):1104-1109
DC‐UbP/UBTD2 is a ubiquitin (Ub) domain‐containing protein first identified from dendritic cells, and is implicated in ubiquitination pathway. The solution structure and backbone dynamics of the C‐terminal Ub‐like (UbL) domain were elucidated in our previous work. To further understand the biological function of DC‐UbP, we then solved the solution structure of the N‐terminal domain of DC‐UbP (DC‐UbP_N) and studied its Ub binding properties by NMR techniques. The results show that DC‐UbP_N holds a novel structural fold and acts as a Ub‐binding domain (UBD) but with low affinity. This implies that the DC‐UbP protein, composing of a combination of both UbL and UBD domains, might play an important role in regulating protein ubiquitination and delivery of ubiquitinated substrates in eukaryotic cells. 相似文献
27.
28.
O. B. Kazakova E. F. Khusnutdinova G. A. Tolstikov K. Yu. Suponitsky 《Russian Journal of Bioorganic Chemistry》2010,36(4):512-515
New olean-18(19)-ene triterpenoids were effectively synthesized by the interaction of allobetulin or its acetate with phosphorous
oxychloride in refluxing pyridine. The structures of the synthesized 17-chloromethyloleane-18(19)-enes were confirmed by NMR
spectroscopy and X-ray analysis. 相似文献
29.
30.
L. A. Piruzyan V. A. Sukhanov E. V. Kalinina T. Yu. Fedorova A. N. Saprin 《Biology Bulletin》2002,29(2):115-119
We studied intraspecific features of the main enzymes of metabolism and detoxication of xenobiotics on mice (eight inbred lines) and rats (five lines) for estimation of possible variants of complete or incomplete metabolic equality. Significant genetically determined intraspecific differences for activities of the enzymes of metabolism and detoxication of xenobiotics were described. Generalized criteria for comparison of the metabolic status were proposed on the basis of activities of the main enzymes: cytochrome P-450 (hydroxylation and epoxidation), epoxyhydrolase, glutathione-S-transferase, UDP-glucuronosyl transferase, and sulfotransferase. The proposed criteria for estimation of the metabolic parameters of an individual can serve as a basis of metabolic portraiting. 相似文献