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31.
32.
催产素在脊髓水平对电针镇痛的影响 总被引:3,自引:0,他引:3
采用玻璃微电极胞外记录和脊髓表面给药的方法观察了催产素(OT)、抗催产素血清(AOTS)以及电针穴位对背角神经元伤害性诱发放电的影响。结果表明:电针穴位或脊髓表面施加OT可部分抑制脊髓背角神经元的伤害性诱发放电;在电针的基础上施加OT则明显加强电针的抑制效应;相反,用AOTS预处理后,电针的抑制作用放取消。提示OT在脊髓水平参与了对痛觉信息的调制,并与一定频率的针刺镇痛有关。 相似文献
33.
Summary Batch cultures of Saccharomycopsis lipolytica were grown in minimal medium with olive oil as carbon source. Inocula of glucose-grown cells commenced growth with little lag at rates largely unaffected by variations in the stirring rate or oil concentration. However, growth rates declined when the medium pH was below 7.0. In all cultures, media pH declined with increasing cell concentration. Cell composition during exponential growth was 42% protein and 2% fat. Carbon-limited cells maintained this composition after oil exhaustion but during nitrogen- and oxygen-limited growth, protein content decreased and fat content increased although the protein decrease was only transient with oxygen limitation. Yield coefficients for triglyceride were near unity for all cultures. Free acid concentrations rose rapidly after inoculation. As fermentations progressed, free glycerol appeared and concentrations of di- and monoglycerides passed through maximal values although peak concentrations of di- and monoglycerides persisted for extended times in oxygen- and nitrogen-limited cultures respectively. The fraction of free glycerol consumed was greater in oxygen-limited than in carbon- or nitrogen-limited culture. The basic requirements for growth of yeasts on fatty wastes are discussed with reference to these observations. 相似文献
34.
Desired family size and contraceptive behavior of 986 ever-married women aged 15-54 from Northern Mindanao, the Philippines, are described. Using the Dow and Werner typology of demographic and contraceptive patterns, it was found that a majority of the women were traditional in their demographic attitude and contraceptive behavior. A substantial proportion of the women desired medium to large families. In consistency in attitude and behavior was also manifested by women who desired small families but have never used efficient family planning methods. Sociodemographic characteristics of these women are described. A majority of the women who have never used efficient contraception also never practiced family planning. Rhythm was the primary method of birth control among demographic innovators and traditionals who have ever used inefficient methods; the pill was popular among contraceptive innovators and moderns. A considerable proportion of the demographic innovators and the traditionals were not currently using any family planning method; a lesser proportion of contraceptive innovators and moderns were also not using birth control methods. Relevance of the findings to family planning programs is pointed out. Recommendations are given. Motivation for a small family is a prerequisite for a successful family planning program. Without motivation, what family planning programs do is reduce the number of unwanted births. Family planning programs should reach out to those who are sufficiently motivated to have small families but have never used efficient family planning methods. A major finding of this research is that a majority of the women who never used efficient contraception also never used inefficient or traditional methods. Efforts should be made to change this. Additionally, efforts should be made to bring those modern and contraceptive innovators who had stopped using any family planning method to practice contraception again. 相似文献
35.
Species of Cunninghamella, Gliocladium deliquescens, Trichoderma harzianum and T. koningii were isolated from rotten wood chips. When grown on medium containing cellulose, all except Cunninghamella produced the three primary enzymes (exoglucanase, endoglucanase and -glucosidase) of the cellulase complex. The patterns for enzyme production, changes in mycelial mass and pH of the induction medium for T. harzianum and T. koningii were closely similar, and were distinguishable from those of G. deliquescens. 相似文献
36.
Uptake of d-glucosamine by rat brain synaptosomes occurs via a saturable transport process (Km 2.1 mM, V 3.0 nmol/mg per min) which was clearly distinguishable from simple diffusion. This transport process is highly sensitive to cytochalasin (Ki = 7 · 10?5 mM. d-Glucose competitively inhibits d-glucosamine uptake with a Ki value of 8 · 10?1 mM. 相似文献
37.
The effect of 2-bromopalmitate, an inhibitor of fatty acid oxidation, on progesterone synthesis in isolated luteal cells was studied. Incubation of the cells with increasing concentrations (0 – 2 mM) of the inhibitor resulted in an initial enhancement of progesterone synthesis, both in the presence and absence of LH (1 μg/m1). In the LH-treated cells, this stimulation in steroid synthesis becomes markedly impaired at 2 mM 2-bromopalmitate. In the control cells, however, progesterone synthesis was sustained at the elevated level. At high concentrations of 2-bromopalmitate, the stimulatory effect of LH (relative to the controls) on steroidogenesis was progressively diminished, until it was completely abolished at an inhibitor concentration of 2 mM. The oxidation of labelled palmitic acid by luteal cells was also effectively inhibited by 2-bromopalmitate (1 mM). The results indicate that the steroidogenic effect of LH is mediated, in part, by fatty acid oxidation, and were explained in terms of the interaction between carbohydrate and fatty acid oxidation in supporting ovarian steroidogenesis. 相似文献
38.
When flax seedlings are decapitated above cotyledons and three days later one of the two cotyledons is removed then the remaining
cotyledon stimulates in four to five days growth of its axillary bud. It has been found that content of endogenous cytokinins
was higher in the stimulated bud as compared with the other one already 12 h after the cotyledon removal.
Flax seedlings decapitated under cotyledons regenerate adventitious buds on thy hypocotyl stump during 5–6 days. The endogenous
fytohormonal preparation of this regeneration was investigated in the 20 mm apical part of the hypocotyl stump. Decrease in
auxin and increase in gibberellins was already found during the first day after decapitation while the level of cytokinins
increased as late as three days after the apex removal. 相似文献
39.
[3H]Mepyramine binds with high affinity to membranes from brain of human, rat, guinea-pig, rabbit and mouse with drug specificity indicating an association with histamine H1receptors. Considerable species differences occur in the affinity of [3H]mepyramine, with guinea-pig and human having 34 times greater affinity than rat, mouse or rabbit. The greater affinity of [3H]mepyramine in guinea-pig than in rat is attributable both to faster association and slower dissociation rates in guinea-pig. Species differences in affinity for H1 receptor sites occur for some antihistamines but not for others. Some tricyclic antidepressant and neuroleptic drugs are extremely potent inhibitors of [3H]mepyramine binding, exceeding in potency any H1 antihistamines examined. The tricyclic antidepressant doxepin and the neuroleptic clozapine are the most potent of all drugs examined in competing for [3H]mepyramine binding. The regional distribution of specific [3H]mepyramine binding differs considerably in the various species examined. 相似文献
40.
Nineteen patients who had completed their course of dermatattoo treatment for the camouflage of port-wine hemangioma were evaluated at an average of 3.1 years following completion of treatment. A panel of 7 people evaluated preoperative and postoperative photographs and judged that none of the patients were more than "50 percent improved" in the camouflaging of their hemangioma, and that most of them (15 out of 19) were either "not improved" or "25 percent improved," as compared to their original photographs. We cannot rule out the possibility that this treatment may be effective in adults, as all of our patients at the time of their first treatment were between the ages of 4 and 20 years; and most of them were between 6 and 10 years old. On the basis of this evaluation, we no longer recommend the technique of dermatattoo for camouflage of port-wine hemangioma in patients in the younger age group. 相似文献