全文获取类型
收费全文 | 642篇 |
免费 | 42篇 |
出版年
2023年 | 3篇 |
2022年 | 5篇 |
2021年 | 4篇 |
2020年 | 6篇 |
2019年 | 9篇 |
2018年 | 11篇 |
2017年 | 7篇 |
2016年 | 9篇 |
2015年 | 30篇 |
2014年 | 31篇 |
2013年 | 33篇 |
2012年 | 51篇 |
2011年 | 45篇 |
2010年 | 24篇 |
2009年 | 21篇 |
2008年 | 28篇 |
2007年 | 35篇 |
2006年 | 33篇 |
2005年 | 44篇 |
2004年 | 32篇 |
2003年 | 31篇 |
2002年 | 22篇 |
2001年 | 8篇 |
2000年 | 7篇 |
1999年 | 6篇 |
1998年 | 4篇 |
1997年 | 9篇 |
1995年 | 5篇 |
1993年 | 6篇 |
1992年 | 5篇 |
1991年 | 11篇 |
1990年 | 4篇 |
1989年 | 5篇 |
1988年 | 3篇 |
1987年 | 4篇 |
1986年 | 3篇 |
1985年 | 7篇 |
1980年 | 3篇 |
1979年 | 3篇 |
1978年 | 3篇 |
1976年 | 5篇 |
1975年 | 5篇 |
1974年 | 5篇 |
1973年 | 11篇 |
1972年 | 4篇 |
1971年 | 6篇 |
1969年 | 4篇 |
1968年 | 5篇 |
1953年 | 2篇 |
1941年 | 2篇 |
排序方式: 共有684条查询结果,搜索用时 328 毫秒
641.
642.
Ana Carolina Brasileiro Ronildo Alves Benício José Guilherme Gonçalves-Sousa Robson Waldemar Ávila 《Austral ecology》2023,48(7):1274-1291
Anthropogenic changes in habitats are one of the main threats to biodiversity. Understanding how species diversity and their functions are affected by these changes is crucial to assess environmental impacts. In this work, we aim to understand how lizard composition, taxonomic and functional diversity respond to differences in native vegetation regeneration stages (conserved vegetation and open secondary vegetation) and agricultural land use in different vegetation types (Caatinga sensu stricto, Cerrado sensu stricto and Relictual Humid Forest) in Caatinga domain, Brazil. In more degraded areas (open secondary vegetation and agricultural areas), we found a decline in species evenness, shown by greater dominance of few species. Moreover, we found a lower functional evenness in agricultural areas than in areas of conserved vegetation, which suggests that a smaller portion of functional traits present greater dominance in more anthropized areas. We did not detect any significant differences in species richness, but we did registered differences in species composition in Relictual Humid Forest. Contrary to our expectations, lizard abundance was also greater in more degraded areas, probably as a result of the increased abundance of species benefited by anthropization. In this work, we advance the knowledge of how anthropogenic changes influence lizard diversity and emphasize the importance of analysing different facets of diversity and different habitat environments to understand how anthropization affects patterns in community ecology. 相似文献
643.
644.
645.
646.
Waldemar Preis Annika Bestehorn Johannes Buchner Martin Haslbeck 《Cell stress & chaperones》2017,22(4):541-552
In humans, ten genes encode small heat shock proteins with lens αA-crystallin and αB-crystallin representing two of the most prominent members. The canonical isoforms of αA-crystallin and αB-crystallin collaborate in the eye lens to prevent irreversible protein aggregation and preserve visual acuity. α-Crystallins form large polydisperse homo-oligomers and hetero-oligomers and as part of the proteostasis system bind substrate proteins in non-native conformations, thereby stabilizing them. Here, we analyzed a previously uncharacterized, alternative splice variant (isoform 2) of human αA-crystallin with an exchanged N-terminal sequence. This variant shows the characteristic α-crystallin secondary structure, exists on its own predominantly in a monomer–dimer equilibrium, and displays only low chaperone activity. However, the variant is able to integrate into higher order oligomers of canonical αA-crystallin and αB-crystallin as well as their hetero-oligomer. The presence of the variant leads to the formation of new types of higher order hetero-oligomers with an overall decreased number of subunits and enhanced chaperone activity. Thus, alternative mRNA splicing of human αA-crystallin leads to an additional, formerly not characterized αA-crystallin species which is able to modulate the properties of the canonical ensemble of α-crystallin oligomers. 相似文献
647.
Triacylglycerol: sterol acyltransferase is present in roots of Sinapis alba seedlings. The enzyme is located predominantly in the cell membrane structures sedimenting at 300–16 000 g but can be solubilized by acetone treatment and buffer extraction. During gel filtration on Sephadex G-100 the acyltransferase activity was separated into two peaks corresponding to MW 1.8 × 1014 and MW ? 105, respectively. A number of natural 3β-hydroxysterols can be esterified by the solubilized acyltransferase. The rate of esterification is much higher for sterols containing a planar ring system. The number and position of double bonds, as well as the structure of the side chain at C- 17 of the sterol molecule, are of secondary importance. Triacylglycerols containing fatty acids C, C6-C22 can be utilized as acyl donors. Among triacylglycerols containing saturated fatty acids, tripalmitoylglycerol (C16:0) is the best acyl donor. For triacylglycerols containing C18-fatty acids the following sequence was observed: trioleoylglycerol (C18:1) > trilinoleoylglycerol (C18:2) > trilinolenoylglycerol (C18:3) > tristearoylglycerol (C18:0). 相似文献
648.
649.
650.
Effects of 253.7 nm ultraviolet radiation on membrane potential and conductance in internodal cells of Nitellopsis obtusa were studied. The radiation caused transient depolarization of plasmalemma and tonoplast and simultaneous increase in electric conductance. These effects were partly reversible and the degree of the recovery depended on the duration of the exposure. In cells with potential difference (between vacuole and external medium) more negative than – 140 mV, the radiation induced an action potential. The hyperpolarized state created by visible light and indole-3-acetic acid was fully suppressed by the radiation. The results are discussed taking into account the data for Chara corallina obtained by C. J. Doughty and A. B. Hope. It is suggested that 253.7 nm radiation inhibits electrogenic proton pumps in the plasmalemma and activates the Cl− channels. 相似文献