全文获取类型
收费全文 | 256篇 |
免费 | 14篇 |
出版年
2021年 | 4篇 |
2016年 | 7篇 |
2015年 | 8篇 |
2014年 | 6篇 |
2013年 | 9篇 |
2012年 | 9篇 |
2011年 | 11篇 |
2010年 | 7篇 |
2009年 | 7篇 |
2007年 | 6篇 |
2006年 | 5篇 |
2005年 | 7篇 |
2004年 | 5篇 |
2003年 | 3篇 |
2002年 | 5篇 |
1993年 | 2篇 |
1992年 | 2篇 |
1974年 | 2篇 |
1973年 | 3篇 |
1970年 | 2篇 |
1969年 | 3篇 |
1967年 | 2篇 |
1966年 | 2篇 |
1965年 | 2篇 |
1964年 | 2篇 |
1963年 | 4篇 |
1962年 | 3篇 |
1961年 | 8篇 |
1960年 | 5篇 |
1959年 | 9篇 |
1958年 | 5篇 |
1956年 | 5篇 |
1955年 | 5篇 |
1953年 | 5篇 |
1951年 | 4篇 |
1950年 | 2篇 |
1949年 | 4篇 |
1948年 | 4篇 |
1947年 | 2篇 |
1946年 | 4篇 |
1944年 | 4篇 |
1942年 | 4篇 |
1939年 | 7篇 |
1938年 | 3篇 |
1937年 | 3篇 |
1936年 | 4篇 |
1935年 | 4篇 |
1932年 | 2篇 |
1931年 | 3篇 |
1930年 | 2篇 |
排序方式: 共有270条查询结果,搜索用时 187 毫秒
121.
Wilfrid Gaisford 《BMJ (Clinical research ed.)》1948,2(4587):969-972
122.
123.
124.
Wilfrid Gaisford 《BMJ (Clinical research ed.)》1954,1(4864):744-745
125.
126.
127.
Andreas Hejnol Matthias Obst Alexandros Stamatakis Michael Ott Greg W. Rouse Gregory D. Edgecombe Pedro Martinez Jaume Bagu?à Xavier Bailly Ulf Jondelius Matthias Wiens Werner E. G. Müller Elaine Seaver Ward C. Wheeler Mark Q. Martindale Gonzalo Giribet Casey W. Dunn 《Proceedings. Biological sciences / The Royal Society》2009,276(1677):4261-4270
A clear picture of animal relationships is a prerequisite to understand how the morphological and ecological diversity of animals evolved over time. Among others, the placement of the acoelomorph flatworms, Acoela and Nemertodermatida, has fundamental implications for the origin and evolution of various animal organ systems. Their position, however, has been inconsistent in phylogenetic studies using one or several genes. Furthermore, Acoela has been among the least stable taxa in recent animal phylogenomic analyses, which simultaneously examine many genes from many species, while Nemertodermatida has not been sampled in any phylogenomic study. New sequence data are presented here from organisms targeted for their instability or lack of representation in prior analyses, and are analysed in combination with other publicly available data. We also designed new automated explicit methods for identifying and selecting common genes across different species, and developed highly optimized supercomputing tools to reconstruct relationships from gene sequences. The results of the work corroborate several recently established findings about animal relationships and provide new support for the placement of other groups. These new data and methods strongly uphold previous suggestions that Acoelomorpha is sister clade to all other bilaterian animals, find diminishing evidence for the placement of the enigmatic Xenoturbella within Deuterostomia, and place Cycliophora with Entoprocta and Ectoprocta. The work highlights the implications that these arrangements have for metazoan evolution and permits a clearer picture of ancestral morphologies and life histories in the deep past. 相似文献
128.
Gregory D. Edgecombe 《Evolution》2009,2(2):178-190
Membership of Arthropoda in a clade of molting animals, the Ecdysozoa, has received a growing body of support over the past
10 years from analyses of DNA sequences from many genes together with morphological characters involving the cuticle and its
molting. Recent analyses based on broad phylogenomic sampling strengthen the grouping of cycloneuralian worms and arthropods
as Ecdysozoa, identify the velvet worms (Phylum Onychophora) as the closest living relatives of arthropods, and interpret
segmentation as having separate evolutionary origins in arthropods and annelid worms. Determining whether the water bears
(Phylum Tardigrada) are more closely related to onychophorans and arthropods or to unsegmented cycloneuralians such as roundworms
(Nematoda) is an open question. Fossil taxa such as the Cambrian anomalocaridids provide a combination of arthropod and cycloneuralian
characters that is not observed in any living ecdysozoan. Fossils break up long branches and help to resolve the sequence
of character acquisition at several critical nodes in the arthropod tree, notably in a suite of Cambrian lobopodians that
may include the stem groups of each of the major panarthropod lineages. 相似文献
129.
Johannes Mischlinger Rella Zoleko Manego Ghyslain Mombo-Ngoma Dorothea Ekoka Mbassi Nina Hackbarth Franck-Aurelien Ekoka Mbassi Saskia Dede Davi Ruth Kreuzmair Luzia Veletzky Jennifer Hergeth Wilfrid Nzebe Ndoumba Paul Pitzinger Mirjam Groger Pierre Blaise Matsiegui Ayla Akim Adegnika Selidji Todagbe Agnandji Bertrand Lell Michael Ramharter 《PLoS neglected tropical diseases》2021,15(8)
BackgroundLoa loa and Mansonella perstans–the causative agents of loiasis and mansonellosis—are vector-borne filarial parasites co-endemic in sub-Saharan Africa. Diagnosis of both infections is usually established by microscopic analysis of blood samples. It was recently established that the odds for detecting Plasmodium spp. is higher in capillary (CAP) blood than in venous (VEN) blood. In analogy to this finding this analysis evaluates potential differences in microfilaraemia of L. loa and M. perstans in samples of CAP and VEN blood.MethodsRecruitment took place between 2015 and 2019 at the CERMEL in Lambaréné, Gabon and its surrounding villages. Persons of all ages presenting to diagnostic services of the research center around noon were invited to participate in the study. A thick smear of each 10 microliters of CAP and VEN blood was prepared and analysed by a minimum of two independent microscopists. Differences of log2-transformed CAP and VEN microfilaraemia were computed and expressed as percentages. Furthermore, odds ratios for paired data were computed to quantify the odds to detect microfilariae in CAP blood versus in VEN blood.ResultsA total of 713 participants were recruited among whom 52% were below 30 years of age, 27% between 30–59 years of age and 21% above 60 years of age. Male-female ratio was 0.84. Among 152 participants with microscopically-confirmed L. loa infection median (IQR) microfilaraemia was 3,650 (275–11,100) per milliliter blood in CAP blood and 2,775 (200–8,875) in VEN blood (p<0.0001), while among 102 participants with M. perstans this was 100 (0–200) and 100 (0–200), respectively (p = 0.44). Differences in linear models amount up to an average of +34.5% (95% CI: +11.0 to +63.0) higher L. loa microfilaria quantity in CAP blood versus VEN blood and for M. perstans it was on average higher by +24.8% (95% CI: +0.0 to +60.5). Concordantly, the odds for detection of microfilaraemia in CAP samples versus VEN samples was 1.24 (95% CI: 0.65–2.34) and 1.65 (95% CI: 1.0–2.68) for infections with L. loa and M. perstans, respectively.ConclusionThis analysis indicates that average levels of microfilaraemia of L. loa are higher in CAP blood samples than in VEN blood samples. This might have implications for treatment algorithms of onchocerciasis and loiasis, in which exact quantification of L. loa microfilaraemia is of importance. Furthermore, the odds for detection of M. perstans microfilariae was higher in CAP than in VEN blood which may pre-dispose CAP blood for detection of M. perstans infection in large epidemiological studies when sampling of large blood quantities is not feasible. No solid evidence for a higher odds of L. loa microfilariae detection in CAP blood was revealed, which might be explained by generally high levels of L. loa microfilaraemia in CAP and VEN blood above the limit of detection of 100 microfilariae/ml. Yet, it cannot be excluded that the study was underpowered to detect a moderate difference. 相似文献
130.
A comparative survey of the epipharynx and hypopharynx of lithobiomorph centipedes by light and scanning electron microscopy examines 18 species that sample the major groups of both families, the Lithobiidae and Henicopidae. Cladistic analysis of 11 characters of the peristomatic structures together with 29 additional morphological characters serves as a basis for interpreting the evolution of the lithobiomorph peristomatic structures. Scutigeromorpha is used for outgroup comparison in the framework of a homology scheme for the basic components of the epi- and hypopharynx. Compared to other chilopods, the monophyly of Lithobiomorpha is supported by a row of distinctive bottle-shaped gland openings at the border between the labral and clypeal parts of the epipharynx, as well as by a distinctive shape of the hypopharynx. Paired rows of elongate spines on the clypeal part of the epipharynx are an apomorphic character of Lithobiidae. The transformation of these spine rows into a few groups of branching spines is characteristic for the Monotarsobius group sensu Verhoeff. Similar groups of branching clypeal spines characterize the Anopsobiinae within Henicopidae, whereas Henicopinae possess a dense cluster of short, simple spines instead. The recently described genus Dzhungaria is resolved closer to Henicopinae than to Anopsobiinae, a hypothesis supported by a field of grooves on the medial labral part of the epipharynx. Monophyly of Henicopidae does not receive unique support from the peristomatic structures although two homoplastic characters contribute to this node; among these, the reduction of a median spine field between clypeal and labral parts of the epipharynx to a narrow transverse band also supports a close relationship between the Ezembius group and Hessebius within Lithobiidae. An Ezembius+Hessebius clade is additionally supported by the absence of a transverse bulge between the clypeal and labral parts of the epipharynx, a character otherwise present in all lithobiomorph species studied so far. Lithobius is resolved as polyphyletic, with different species being most closely related to such genera as Australobius, Hessebius and Pleurolithobius. 相似文献