全文获取类型
收费全文 | 1021篇 |
免费 | 146篇 |
国内免费 | 1篇 |
出版年
2021年 | 11篇 |
2020年 | 19篇 |
2019年 | 45篇 |
2018年 | 36篇 |
2017年 | 8篇 |
2016年 | 16篇 |
2015年 | 13篇 |
2014年 | 23篇 |
2013年 | 38篇 |
2012年 | 37篇 |
2011年 | 21篇 |
2010年 | 33篇 |
2009年 | 18篇 |
2008年 | 39篇 |
2007年 | 33篇 |
2006年 | 40篇 |
2005年 | 22篇 |
2004年 | 18篇 |
2003年 | 13篇 |
2002年 | 30篇 |
2001年 | 28篇 |
2000年 | 20篇 |
1999年 | 24篇 |
1998年 | 22篇 |
1997年 | 18篇 |
1996年 | 21篇 |
1995年 | 24篇 |
1994年 | 14篇 |
1993年 | 15篇 |
1992年 | 26篇 |
1991年 | 25篇 |
1990年 | 38篇 |
1989年 | 44篇 |
1988年 | 21篇 |
1987年 | 31篇 |
1986年 | 23篇 |
1985年 | 19篇 |
1984年 | 23篇 |
1983年 | 13篇 |
1982年 | 10篇 |
1981年 | 11篇 |
1980年 | 11篇 |
1979年 | 16篇 |
1978年 | 13篇 |
1977年 | 10篇 |
1976年 | 9篇 |
1975年 | 16篇 |
1974年 | 12篇 |
1973年 | 9篇 |
1972年 | 8篇 |
排序方式: 共有1168条查询结果,搜索用时 46 毫秒
161.
A cancer microenvironment generates strong hydrogen bond network system by the positive feedback loops supporting cancer complexity and robustness. Such network functions through the AKT locus generating high entropic energy supporting cancer metastatic robustness. Charged lepton particle muon follows the rule of Bragg effect during a collision with hydrogen network in cancer cells. Muon beam dismantles hydrogen bond network in cancer by the muon-catalyzed fusion, leading to apoptosis of cancer cells. Muon induces cumulative energy appearance on the hydrogen bond network in a cancer cell with its fast decay to an electron and two neutrinos. Thus, muon beam, muonic atom, muon neutrino shower, and electrons simultaneously cause fast neutralization of the AKT hydrogen bond network by the conversion of hydrogen into deuterium or helium, inactivating the hydrogen bond networks and inducing failure of cancer complexity and robustness with the disappearance of a malignant phenotype. 相似文献
162.
Cheng Qian MD Danqi Chang MD Hang Li MD Yanggan Wang 《Journal of cellular biochemistry》2019,120(5):7771-7777
Heart failure (HF) remains a common complication after acute ST-segment elevation myocardial infarction (STEMI). Here, we aim to identify critical genes related to the developed HF in patients with STEMI using bioinformatics analysis. The microarray data of GSE59867, including peripheral blood samples from nine patients with post-infarct HF and eight patients without post-infarct HF, were downloaded from the Gene Expression Omnibus database. Differentially expressed genes (DEGs) between HF and non-HF groups were screened by LIMMA package. Functional enrichment analyses of DEGs were conducted, followed by construction of a protein-protein interaction (PPI) network. The dynamic messenger RNA (mRNA) level of the hub genes during the follow-up was analyzed to further elucidate their role in HF development. A total of 58 upregulated and 75 downregulated DEGs were screen out. They were mainly enriched in biological processes about inflammatory response, extracellular matrix organization, response to cAMP, immune response, and positive regulation of cytosolic calcium ion concentration. Pathway analysis revealed that the DEGs were also involved in hematopoietic cell lineage, pathways in cancer, and extracellular matrix-receptor interaction. In the PPI network consisting of 58 nodes and 72 interactions, CXCL8 (degree = 15), THBS1 (degree = 8), FOS (degree = 7), and ITGA2B (degree = 6) were identified as the hub genes. In the comparison of patients with and without post-infarct HF, the mRNA level of these hub genes were all higher within 30 days but reached similar at 6 months after STEMI. In conclusion, CXCL8, THBS1, FOS, and ITGA2B may play important roles in the development of HF after acute STEMI. 相似文献
163.
Scoggin C. H.; Doekel R. D.; Kryger M. H.; Zwillich C. W.; Weil J. V. 《Journal of applied physiology》1978,44(3):464-468
164.
165.
A plaque assay for polyoma virus using primary baby mouse kidney cells is reported. 相似文献
166.
167.
168.
Rolf Frischknecht Christian Bauer Christof Bucher Linda Ager-Wick Ellingsen Lukas Gutzwiller Britta Heimbach René Itten Xun Liao Evangelos Panos Stephan Pfister Tobias Schmidt Valentin Stahel Philippe Stolz Peter Toggweiler Karin Treyer Jacques Villeneuve Andreas Wade Marcel Weil 《The International Journal of Life Cycle Assessment》2018,23(8):1716-1721
169.
170.
Nucleotide sequences of three soybean chloroplast tRNAsLeu and re-examination of bean chloroplast tRNA2Leu sequence. 总被引:6,自引:3,他引:3
下载免费PDF全文
![点击此处可从《Nucleic acids research》网站下载免费的PDF全文](/ch/ext_images/free.gif)
The nucleotide sequences of soybean chloroplast tRNAsLeu were determined using post-labeling techniques. Comparison of the primary structures of soybean chloroplast tRNAsLeu with their bean, maize and spinach counterparts only show few base differences. Contrary to previously published results (1) a re-examination of bean tRNALeu sequence shows that this tRNA resembles soybean and maize tRNA2Leu in structure. 相似文献