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51.
Rampant horizontal transfer and duplication of rubisco genes in eubacteria and plastids 总被引:14,自引:2,他引:14
Previous work has shown that molecular phylogenies of plastids,
cyanobacteria, and proteobacteria based on the rubisco (ribulose-1,5-
bisphosphate carboxylase/oxygenase) genes rbcL and rbcS are incongruent
with molecular phylogenies based on other genes and are also incompatible
with structural and biochemical information. Although it has been much
speculated that this is the consequence of a single horizontal gene
transfer (of a proteobacterial or mitochondrial rubisco operon into
plastids of rhodophytic and chromophytic algae), neither this hypothesis
nor the alternative hypothesis of ancient gene duplication have been
examined in detail. We have conducted phylogenetic analyses of all
available bacterial rbcL sequences, and representative plastid sequences,
in order to explore these alternative hypothesis and fully examine the
complexity of rubisco gene evolution. The rbcL phylogeny reveals a
surprising number of gene relationships that are fundamentally incongruent
with organismal relationships as inferred from multiple lines of other
molecular evidence. On the order of six horizontal gene transfers are
implied by the form I (L8S8) rbcL phylogeny, two between cyanobacteria and
proteobacteria, one between proteobacteria and plastids, and three within
proteobacteria. Alternatively, a single ancient duplication of the form I
rubisco operon, followed by repeated and pervasive differential loss of one
operon or the other, would account for much of this incongruity. In all
probability, the rubisco operon has undergone multiple events of both
horizontal gene transfer and gene duplication in different lineages.
相似文献
52.
Joe Walston John G. Robinson Elizabeth L. Bennett Urs Breitenmoser Gustavo A. B. da Fonseca John Goodrich Melvin Gumal Luke Hunter Arlyne Johnson K. Ullas Karanth Nigel Leader-Williams Kathy MacKinnon Dale Miquelle Anak Pattanavibool Colin Poole Alan Rabinowitz James L. D. Smith Emma J. Stokes Simon N. Stuart Chanthavy Vongkhamheng Hariyo Wibisono 《PLoS biology》2010,8(9)
53.
Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein 下载免费PDF全文
Reiner AP Barber MJ Guan Y Ridker PM Lange LA Chasman DI Walston JD Cooper GM Jenny NS Rieder MJ Durda JP Smith JD Novembre J Tracy RP Rotter JI Stephens M Nickerson DA Krauss RM 《American journal of human genetics》2008,82(5):1193-1201
Data from the Pharmacogenomics and Risk of Cardiovascular Disease (PARC) study and the Cardiovascular Health Study (CHS) provide independent and confirmatory evidence for association between common polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha and plasma C-reactive protein (CRP) concentration. Analyses with the use of imputation-based methods to combine genotype data from both studies and to test untyped SNPs from the HapMap database identified several SNPs within a 5 kb region of HNF1A intron 1 with the strongest evidence of association with CRP phenotype. 相似文献
54.
Low serum selenium concentrations are associated with poor grip strength among older women living in the community 总被引:2,自引:0,他引:2
Beck J Ferrucci L Sun K Walston J Fried LP Varadhan R Guralnik JM Semba RD 《BioFactors (Oxford, England)》2007,29(1):37-44
Aging is associated with a loss of muscle strength, and, in turn, loss of muscle strength has been associated with increased risk of frailty, disability and mortality. The factors that contribute to loss of muscle strength with aging have not been well characterized. Selenium is important in normal muscle function because of its role in selenoenzymes that protect muscle against oxidative damage. We hypothesized that low serum selenium concentrations were associated with poor grip strength. We examined the association between serum selenium and hand grip strength among 676 moderately to severely disabled community-dwelling women in the Women's Health and Aging Study I in Baltimore, Maryland. After adjusting for age, race, body mass index, Mini-Mental Status Examination score, current smoking, hypertension, congestive heart failure and depression, serum selenium was associated with grip strength (P=0.04). This study supports the idea that selenium is important to muscle strength in older women. 相似文献
55.
56.
Suman R. Rawat Minna K. M?nnist? Valentin Starovoytov Lynne Goodwin Matt Nolan Loren J. Hauser Miriam Land Karen Walston Davenport Tanja Woyke Max M. H?ggblom 《Standards in genomic sciences》2013,9(1):71-82
Granulicella mallensis MP5ACTX8T is a novel species of the genus Granulicella in subdivision 1of Acidobacteria. G. mallensis is of ecological interest being a member of the dominant soil bacterial community active at low temperatures and nutrient limiting conditions in Arctic alpine tundra. G. mallensis is a cold-adapted acidophile and a versatile heterotroph that hydrolyzes a suite of sugars and complex polysaccharides. Genome analysis revealed metabolic versatility with genes involved in metabolism and transport of carbohydrates. These include gene modules encoding the carbohydrate-active enzyme (CAZyme) family involved in breakdown, utilization and biosynthesis of diverse structural and storage polysaccharides including plant based carbon polymers. The genome of Granulicella mallensis MP5ACTX8T consists of a single replicon of 6,237,577 base pairs (bp) with 4,907 protein-coding genes and 53 RNA genes. 相似文献
57.
Suman R. Rawat Minna K. M?nnist? Valentin Starovoytov Lynne Goodwin Matt Nolan Lauren Hauser Miriam Land Karen Walston Davenport Tanja Woyke Max M. H?ggblom 《Standards in genomic sciences》2012,7(1):59-69
Terriglobus saanensis SP1PR4T is a novel species of the genus Terriglobus. T. saanensis is of ecological interest because it is a representative of the phylum Acidobacteria, which are dominant members of bacterial soil microbiota in Arctic ecosystems. T. saanensis is a cold-adapted acidophile and a versatile heterotroph utilizing a suite of simple sugars and complex polysaccharides. The genome contained an abundance of genes assigned to metabolism and transport of carbohydrates including gene modules encoding for carbohydrate-active enzyme (CAZyme) family involved in breakdown, utilization and biosynthesis of diverse structural and storage polysaccharides. T. saanensis SP1PR4T represents the first member of genus Terriglobus with a completed genome sequence, consisting of a single replicon of 5,095,226 base pairs (bp), 54 RNA genes and 4,279 protein-coding genes. We infer that the physiology and metabolic potential of T. saanensis is adapted to allow for resilience to the nutrient-deficient conditions and fluctuating temperatures of Arctic tundra soils. 相似文献
58.
59.
van Passel MW Kant R Palva A Lucas S Copeland A Lapidus A Glavina del Rio T Dalin E Tice H Bruce D Goodwin L Pitluck S Davenport KW Sims D Brettin TS Detter JC Han S Larimer FW Land ML Hauser L Kyrpides N Ovchinnikova G Richardson PP de Vos WM Smidt H Zoetendal EG 《Journal of bacteriology》2011,193(9):2373-2374
Victivallis vadensis ATCC BAA-548 represents the first cultured representative from the novel phylum Lentisphaerae, a deep-branching bacterial lineage. Few cultured bacteria from this phylum are known, and V. vadensis therefore represents an important organism for evolutionary studies. V. vadensis is a strictly anaerobic sugar-fermenting isolate from the human gastrointestinal tract. 相似文献
60.
Suman R. Rawat Minna K. M?nnist? Valentin Starovoytov Lynne Goodwin Matt Nolan Loren Hauser Miriam Land Karen Walston Davenport Tanja Woyke Max M. H?ggblom 《Standards in genomic sciences》2014,9(3):449-461
Granulicella tundricola strain MP5ACTX9T is a novel species of the genus Granulicella in subdivision 1 Acidobacteria. G. tundricola is a predominant member of soil bacterial communities, active at low temperatures and nutrient limiting conditions in Arctic alpine tundra. The organism is a cold-adapted acidophile and a versatile heterotroph that hydrolyzes a suite of sugars and complex polysaccharides. Genome analysis revealed metabolic versatility with genes involved in metabolism and transport of carbohydrates, including gene modules encoding for the carbohydrate-active enzyme (CAZy) families for the breakdown, utilization and biosynthesis of diverse structural and storage polysaccharides such as plant based carbon polymers. The genome of G. tundricola strain MP5ACTX9T consists of 4,309,151 bp of a circular chromosome and five mega plasmids with a total genome content of 5,503,984 bp. The genome comprises 4,705 protein-coding genes and 52 RNA genes. 相似文献