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281.
282.
H. J. Vonk 《Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology》1929,9(4):685-702
Ohne Zusammenfassung 相似文献
283.
Maged1, a new regulator of skeletal myogenic differentiation and muscle regeneration 总被引:1,自引:0,他引:1
Tuan HN Nguyen Mathieu JM Bertrand Christiane Sterpin Younes Achouri Olivier RY De Backer 《BMC cell biology》2010,11(1):57
Background
In normal adult skeletal muscle, cell turnover is very slow. However, after an acute lesion or in chronic pathological conditions, such as primary myopathies, muscle stem cells, called satellite cells, are induced to proliferate, then withdraw definitively from the cell cycle and fuse to reconstitute functional myofibers. 相似文献284.
Sylwia M. Figarska Judith M. Vonk Cleo C. van Diemen Dirkje S. Postma H. Marike Boezen 《PloS one》2013,8(7)
The ADAM33 gene is associated with the pathophysiology of Chronic Obstructive Pulmonary Disease (COPD) and atherosclerosis. In this study we investigated all-cause, COPD and cardiovascular mortality, in relation to single nucleotide polymorphisms (SNPs) in ADAM33 (Q_1, S_1, S_2, T_1 and T_2) that were genotyped in 1,390 subjects from the Vlagtwedde/Vlaardingen cohort. Participants were examined at entry in 1989/1990 and followed up till evaluation of the vital status on December 31st, 2008. Using Cox proportional hazards regression we estimated the risk of the SNPs in relation to mortality, adjusting for gender, age, FEV1, height, place of residence and packyears of smoking. Additionally, we performed stratified analyses according to gender and smoking habits. After 18 years, 284 (20.4%) subjects had died (107 due to cardiovascular disease and 20 due to COPD). Individuals homozygous for the minor allele of SNP T_2 had an increased risk of all-cause and cardiovascular mortality compared to wild types: hazard ratio 3.6 (95% confidence interval 2.0 to 6.7) and 3.4 (1.2 to 9.5) respectively. Individuals homozygous for the minor allele of S_1, S_2, T_2 or Q_1 had a significantly increased risk of COPD mortality. In stratified analyses the risk of all-cause mortality associated with SNP T_2 did not change: females 3.5 (1.5 to 8.3), males 3.1 (1.2 to 7.6), never smokers 3.8 (0.9 to 16.3), ever smokers 3.6 (1.8 to 7.2). This study shows for the first time that ADAM33 is a pleiotropic gene that is associated with all-cause, COPD and cardiovascular mortality, independent of potential confounders. 相似文献
285.
Ingolfiella arganoi
sp. n. from Abd al Kuri Island in the Arabian Sea is described from two specimens, a male and a female. The western shore of the Indian Ocean was hitherto a vacant spot in the distribution of circumtropical shallow marine interstitial ingolfiellids and therefore the location of the new species fills a meaningful gap in the geography of the family. Morphologically, the new species shows close affinities with Ingolfiella xarifae from the Maldives. 相似文献
286.
287.
Evolution of SINE S1 retroposons in Cruciferae plant species 总被引:3,自引:0,他引:3
Lenoir A; Cournoyer B; Warwick S; Picard G; Deragon JM 《Molecular biology and evolution》1997,14(9):934-941
The S1 element is a plant short interspersed element (SINE) that was first
described and studied in Brassica napus. In this work, we investigated the
distribution and the molecular phylogeny of the S1 element within the
Cruciferae (= Brassicaceae). S1 elements were found to be widely
distributed within the Cruciferae, especially in species of the tribe
Brassiceae. The molecular phylogeny of S1 elements in eight Cruciferae
species (Brassica oleracea, Brassica rapa, Brassica napus, Brassica nigra,
Sinapis, arvensis, Sinapis pubescens, Coincya monensis, and Vella spinosa)
was inferred using 14-36 elements per species. Significant neighbor-joining
and maximum-parsimony phylogenetic clusters, supported by high bootstrap P
values and/or represented in 100% of the most-parsimonious trees, were
observed for each species. Most of these clusters probably correspond to
recent species-specific bursts of S1 amplification. Since these species
diverged recently, S1 amplification in Cruciferae plants is proposed to be
a highly dynamic process that could contribute to genome rearrangements and
eventually lead to reproductive isolation. S1 sequence analysis also
revealed putative gene conversion events that occurred between different S1
elements of a given species. These events suggest that gene conversion is a
minor but significant component of the molecular drive governing S1
concerted evolution.
相似文献
288.
289.
290.
Mari?tte T. W. Vervoort J. Arie Vonk Paul J. W. Mooijman Sven J. J. Van den Elsen Hanny H. B. Van Megen Peter Veenhuizen Renske Landeweert Jaap Bakker Christian Mulder Johannes Helder 《PloS one》2012,7(10)
Soils are among the most complex, diverse and competitive habitats on Earth and soil biota are responsible for ecosystem services such as nutrient cycling, carbon sequestration and remediation of freshwater. The extreme biodiversity prohibits the making of a full inventory of soil life. Hence, an appropriate indicator group should be selected to determine the biological condition of soil systems. Due to their ubiquity and the diverse responses to abiotic and biotic changes, nematodes are suitable indicators for environmental monitoring. However, the time-consuming microscopic analysis of nematode communities has limited the scale at which this indicator group is used. In an attempt to circumvent this problem, a quantitative PCR-based tool for the detection of a consistent part of the soil nematofauna was developed based on a phylum-wide molecular framework consisting of 2,400 full-length SSU rDNA sequences. Taxon-specific primers were designed and tested for specificity. Furthermore, relationships were determined between the quantitative PCR output and numbers of target nematodes. As a first field test for this DNA sequence signature-based approach, seasonal fluctuations of nematode assemblages under open canopy (one field) and closed canopy (one forest) were monitored. Fifteen taxa from four feeding guilds (covering ∼ 65% of the free-living nematode biodiversity at higher taxonomical level) were detected at two trophic levels. These four feeding guilds are composed of taxa that developed independently by parallel evolution and we detected ecologically interpretable patterns for free-living nematodes belonging to the lower trophic level of soil food webs. Our results show temporal fluctuations, which can be even opposite within taxa belonging to the same guild. This research on nematode assemblages revealed ecological information about the soil food web that had been partly overlooked. 相似文献