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Zusammenfassung Das Epithel der Kopfanhänge von elf marinen und Süßwasserprosobranchiern besteht aus prismatischen bis kubischen Stützzellen mit meist dichtem Mikrovillussaum und z.T. Pigmentgranula sowie Sinneszellen, die fast immer in Form sekundärer Sinneszellen vorliegen; nur bei Patella coerulea kommen vermutlich auch primäre Sinneszellen vor. Ihr Zytoplasma ist apikal durch glattwandige E. R.-Zisternen, helle Bläschen und Mikrotubuli gekennzeichnet. Außerdem tragen diese Zellen Zilien und stehen basal mit Nervenendigungen in Kontakt, die sich in drei Gruppen einteilen lassen: 1. Vermutlich cholinerge Endigungen mit optisch leeren Bläschen (Ø 600–800 Å). 2. Endigungen mit dense core vesicles (Ø 1000–1100 Å). Die Annahme, daß diese Endigungen biogene Amine enthalten, wird durch fluoreszenzmikroskopische Befunde gestützt. 3. Endigungen mit großen (Ø 3000–4000 Å) neurosekretorischen Elementargranula.
Structure and innervation of the cephalic tentacles of Prosobranch molluscs
Summary The epithelium of the cephalic tentacles of eleven marine and freshwater prosobranch snails consists of villus bearing supporting cells, which partly contain pigment granules, and sensory cells, which occur in form of secondary sensory cells with the exception of Patella coerulea which presumably possesses primary sensory cells. These receptor cells are characterized as chemoreceptors by apical cilia, smooth surfaced E.R., microtubulues and empty vesicles. At their bases they are in close contact with nerve endings which can be classified in three groups: 1. presumably cholinergic endings with clear vesicles (Ø 600–800 Å). 2. endings with dense core vesicles (Ø 1000–1100 Å). The assumption that these endings contain biogenic amines is supported by positive fluorescence microscopical tests. 3. Endings with big (Ø 3000–4000 Å) neurosecretory elementary granules.
Herrn Prof. Dr. W. Bargmann danke ich für die Überlassung eines Arbeitsplatzes im Anatomischen Institut Kiel. 相似文献
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Inducible degradation of hydroxyproline in Pseudomonas putida: pathway regulation and hydroxyproline uptake 总被引:3,自引:0,他引:3 下载免费PDF全文
Studies in Pseudomonas putida of the inducible degradation of hydroxyproline to alpha-ketoglutarate have indicated that either of the two epimers, hydroxy-l-proline or allohydroxy-d-proline, acts as an inducer of all the pathway enzymes. In a mutant lacking the first enzyme of the sequence, hydroxyproline-2-epimerase, which interconverts these two hydroxyproline epimers, either epimer is still equally active as an inducer of the remaining three enzymes, suggesting that each epimer has intrinsic inducer activity. The second and third enzymes of the sequence were induced coordinately. The induction process appeared to be insensitive to catabolite repression under a number of experimental conditions. The induced enzymes were stable even under conditions of nitrogen starvation and other conditions designed to increase protein turnover. In addition to inducing the degradative enzymes, the two hydroxyproline epimers were also found to induce an uptake system that concentrates hydroxyproline intracellularly. Either amino acid induced the uptake system for its epimer as well as for itself. 相似文献
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Proteolysis and myelin breakdown: a review of recent histochemical and biochemical studies 总被引:9,自引:0,他引:9
Synopsis Proteins are important constituents of the myelin sheath and serve to maintain its structural integrity. One of the protein components is susceptible to tryptic digestion and may be regarded as a particularly vulnerable part of the myelin sheath. The initial events in myelin breakdown may involve disruption of lipid-protein attachments followed later by chemical degradation of released lipids.In Wallerian degeneration the activity of proteolytic enzymes increases by 12 hr after nerve section. Proteolytic enzyme activity increases in the prodromal phase of diphtheritic neuropathy. Extracts of degenerating nerve cause proteolysis of normal myelin with loss of trypanophilic basic protein and lipid; selective loss of basic protein occurs very early in Wallerian degeneration and has also been found in and around plaques of multiple sclerosis. Proteolytic activity is increased at the edges of active multiple sclerosis lesions. It has been shown that the basic encephalitogenic protein is susceptible to digestion by neural proteases, yielding an active encephalitogenic fragment.It is inferred from these collective observations that proteases play an important role in early myelin breakdown and may also be implicated in the pathogenesis of multiple sclerosis plaques by digesting basic protein, by releasing lipid from its attachment to such protein, and by liberating an active encephalitogenic peptide. The factors responsible for the activation and release of proteases remain unknown.Research Associate supported by the Multiple Sclerosis Society. 相似文献
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Developmental potential of single blastomeres of the rabbit egg 总被引:2,自引:0,他引:2
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A new glycolipid sulfate ester in Halobacterium cutirubrum 总被引:7,自引:0,他引:7
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