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Vivian Flinte Ethel Hentz Barbara Mascarenhas Morgado Anne Caruliny do Monte Lima Gabriel Khattar Ricardo Ferreira Monteiro Margarete Valverde de Macedo 《ZooKeys》2015,(547):119-132
The population phenology of the cassidines, Coptocycla
arcuata and Omaspides
trichroa, and the chrysomeline, Platyphora
axillaris, was studied at Serra dos Órgãos National Park, State of Rio de Janeiro, southeast Brazil. Monthly surveys of larvae and adults were conducted between 2008 and 2011 at approximately 1000 m altitude on their respective host plants, Cordia
polycephala (Boraginaceae), Ipomoea
philomega (Convolvulaceae) and Solanum
scuticum (Solanaceae). This is the first observation of larviparity and host record for Platyphora
axillaris. Although having different life history traits, all species showed similar phenologies. They were abundant from October to March, months of high temperatures and intense rainfall, with two distinct reproductive peaks in the same season. Abundance dropped abruptly during the coldest and driest months, from May to August. Frequently none of these species were recorded during June and July. This phenological pattern is similar to other Chrysomelidae living in subtropical areas of Brazil. Temperature and rainfall appear to be the major factors influencing the fluctuation of these three species. 相似文献
105.
Low muscle strength is observed during the peri-and postmenopausal periods, when the secretion of ovarian hormones is drastically
reduced. It is also a predictive of adverse health events as well as incident mobility limitation and disability. The objective
of the present study is to study the biochemical and the histological changes in the skeletal muscle of premature menopause-induced
rats and the possible protective role of L-carnitine. Ovariectomized (OVX) rats were gavaged with L-carnitine (100 mg/kg)
daily for 60 days starting from the second post-operative day. Serum levels of estradiol and markers of skeletal muscle damage
(creatine kinase and lactic dehydrogenase activities) were determined. Light and electron microscopic study of the quadriceps
femoris muscle (QFM) specimens were done. OVX rats showed significant decrease in the serum estradiol level with significant
increase the markers for skeletal muscle damage. Histopathological examination of the QFM showed degenerated myofibers, apoptotic
changes and compensatory hypertrophy. Degenerated mitochondria, multiple lysosomes and lipid droplets among the damaged myofibrils
were also noticed. L-carnitine administration to the OVX rats resulted in non-significant change in the serum estradiol level
with significant attenuation of skeletal muscle damage either biochemically or histopathologically. In conclusion, L-carnitine
administration recovered muscle degeneration after ovariectomy. This finding suggested that L-carnitine could be recommended in the management of post-menopausal myopathy. 相似文献
106.
Levy MZ Small DS Vilhena DA Bowman NM Kawai V Cornejo del Carpio JG Cordova-Benzaquen E Gilman RH Bern C Plotkin JB 《PLoS computational biology》2011,7(9):e1002146
Vector-borne transmission of Chagas disease has become an urban problem in the city of Arequipa, Peru, yet the debilitating symptoms that can occur in the chronic stage of the disease are rarely seen in hospitals in the city. The lack of obvious clinical disease in Arequipa has led to speculation that the local strain of the etiologic agent, Trypanosoma cruzi, has low chronic pathogenicity. The long asymptomatic period of Chagas disease leads us to an alternative hypothesis for the absence of clinical cases in Arequipa: transmission in the city may be so recent that most infected individuals have yet to progress to late stage disease. Here we describe a new method, epicenter regression, that allows us to infer the spatial and temporal history of disease transmission from a snapshot of a population's infection status. We show that in a community of Arequipa, transmission of T. cruzi by the insect vector Triatoma infestans occurred as a series of focal micro-epidemics, the oldest of which began only around 20 years ago. These micro-epidemics infected nearly 5% of the community before transmission of the parasite was disrupted through insecticide application in 2004. Most extant human infections in our study community arose over a brief period of time immediately prior to vector control. According to our findings, the symptoms of chronic Chagas disease are expected to be absent, even if the strain is pathogenic in the chronic phase of disease, given the long asymptomatic period of the disease and short history of intense transmission. Traducción al espa?ol disponible en Alternative Language Text S1/A Spanish translation of this article is available in Alternative Language Text S1. 相似文献
107.
Wang P Holst C Andersen MR Astrup A Bouwman FG van Otterdijk S Wodzig WK van Baak MA Larsen TM Jebb SA Kafatos A Pfeiffer AF Martinez JA Handjieva-Darlenska T Kunesova M Saris WH Mariman EC 《PloS one》2011,6(2):e16773
Background
Weight regain after weight loss is common. In the Diogenes dietary intervention study, high protein and low glycemic index (GI) diet improved weight maintenance.Objective
To identify blood predictors for weight change after weight loss following the dietary intervention within the Diogenes study.Design
Blood samples were collected at baseline and after 8-week low caloric diet-induced weight loss from 48 women who continued to lose weight and 48 women who regained weight during subsequent 6-month dietary intervention period with 4 diets varying in protein and GI levels. Thirty-one proteins and 3 steroid hormones were measured.Results
Angiotensin I converting enzyme (ACE) was the most important predictor. Its greater reduction during the 8-week weight loss was related to continued weight loss during the subsequent 6 months, identified by both Logistic Regression and Random Forests analyses. The prediction power of ACE was influenced by immunoproteins, particularly fibrinogen. Leptin, luteinizing hormone and some immunoproteins showed interactions with dietary protein level, while interleukin 8 showed interaction with GI level on the prediction of weight maintenance. A predictor panel of 15 variables enabled an optimal classification by Random Forests with an error rate of 24±1%. A logistic regression model with independent variables from 9 blood analytes had a prediction accuracy of 92%.Conclusions
A selected panel of blood proteins/steroids can predict the weight change after weight loss. ACE may play an important role in weight maintenance. The interactions of blood factors with dietary components are important for personalized dietary advice after weight loss.Registration
ClinicalTrials.gov NCT00390637相似文献108.
Rachel P. Wildman Aileen P. McGinn Juan Lin Dan Wang Paul Muntner Hillel W. Cohen Kristi Reynolds Vivian Fonseca Mary‐Fran R. Sowers 《Obesity (Silver Spring, Md.)》2011,19(4):853-860
It remains unclear whether abdominal obesity increases cardiovascular disease (CVD) risk independent of the metabolic abnormalities that often accompany it. Therefore, the objective of this study was to evaluate the independent effects of abdominal obesity vs. metabolic syndrome and diabetes on the risk for incident coronary heart disease (CHD) and stroke. The Framingham Offspring, Atherosclerosis Risk in Communities, and Cardiovascular Health studies were pooled to assess the independent effects of abdominal obesity (waist circumference >102 cm for men and >88 cm for women) vs. metabolic syndrome (excluding the waist circumference criterion) and diabetes on risk for incident CHD and stroke in 20,298 men and women aged ≥45 years. The average follow‐up was 8.3 (s.d. 1.9) years. There were 1,766 CVD events. After adjustment for demographic factors, smoking, alcohol intake, number of metabolic syndrome components, and diabetes, abdominal obesity was not significantly associated with an increased risk of CVD (hazard ratio (HR) (95% confidence interval): 1.09 (0.98, 1.20)). However, after adjustment for demographics, smoking, alcohol intake, and abdominal obesity, having 1–2 metabolic syndrome components, the metabolic syndrome and diabetes were each associated with a significantly increased risk of CVD (2.12 (1.80, 2.50), 2.82 (1.92, 4.12), and 5.33 (3.37, 8.41), respectively). Although abdominal obesity is an important clinical tool for identification of individuals likely to possess metabolic abnormalities, these data suggest that the metabolic syndrome and diabetes are considerably more important prognostic indicators of CVD risk. 相似文献
109.
Tage Astrup 《Archives of biochemistry and biophysics》1951,31(3):462-463
110.