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41.
Background
Modelling proteins with multiple domains is one of the central challenges in Structural Biology. Although homology modelling has successfully been applied for prediction of protein structures, very often domain-domain interactions cannot be inferred from the structures of homologues and their prediction requiresab initiomethods. Here we present a new structural prediction approach for modelling two-domain proteins based on rigid-body domain-domain docking. 相似文献42.
Jung Soh Paul MK Gordon Morgan L Taschuk Anguo Dong Andrew C Ah-Seng Andrei L Turinsky Christoph W Sensen 《BMC bioinformatics》2008,9(1):450