全文获取类型
收费全文 | 692篇 |
免费 | 59篇 |
专业分类
751篇 |
出版年
2024年 | 1篇 |
2023年 | 6篇 |
2022年 | 7篇 |
2021年 | 12篇 |
2020年 | 4篇 |
2019年 | 10篇 |
2018年 | 13篇 |
2017年 | 9篇 |
2016年 | 14篇 |
2015年 | 34篇 |
2014年 | 27篇 |
2013年 | 52篇 |
2012年 | 55篇 |
2011年 | 47篇 |
2010年 | 33篇 |
2009年 | 40篇 |
2008年 | 30篇 |
2007年 | 43篇 |
2006年 | 40篇 |
2005年 | 35篇 |
2004年 | 33篇 |
2003年 | 43篇 |
2002年 | 39篇 |
2001年 | 7篇 |
2000年 | 8篇 |
1999年 | 6篇 |
1998年 | 18篇 |
1997年 | 10篇 |
1996年 | 11篇 |
1995年 | 7篇 |
1994年 | 7篇 |
1993年 | 2篇 |
1992年 | 7篇 |
1991年 | 2篇 |
1990年 | 6篇 |
1989年 | 5篇 |
1988年 | 6篇 |
1987年 | 3篇 |
1986年 | 3篇 |
1985年 | 3篇 |
1983年 | 4篇 |
1982年 | 2篇 |
1977年 | 1篇 |
1976年 | 1篇 |
1975年 | 3篇 |
1973年 | 1篇 |
1953年 | 1篇 |
排序方式: 共有751条查询结果,搜索用时 15 毫秒
741.
One hypothesis for the evolution of maleness in plants postulates the following: male plants appear that have re-allocated resources from female parts into a larger number of male flowers, creating a larger floral display. Pollinators respond “dramatically” to the increased display, driving the spread of males in the population (Bawa, K. S., 1980, Annual Review of Ecology and Systematics 11:15–40). To test this, we measured the total number of flowers and the size of male displays in dioecious Sagittaria latifolia and monoecious S. australis. We also measured how fast visitors arrived at “target” flowers in the displays. Then we used the Cox Model, a failure time analysis procedure, to analyze the relationship between visitor arrival and display size. We found that male display sizes were somewhat larger in the dioecious than the monoecious plants, but this was due to more compressed blooming rather than to a larger total number of flowers. The visitors to both plants were similar arrays of generalist bees. Visitors did not show the predicted “dramatic” response, however, but rather a plateauing response to larger display sizes, so our results do not support the hypothesis. Reviewing the literature, we found no reports of the “dramatic” response the hypothesis asserts. Instead, relative insensitivity to display size is the rule. 相似文献
742.
743.
744.
Xu Xiao Ming Chen Aqing Guenard Veronique Kleitman Naomi Bunge Mary Bartlett 《Brain Cell Biology》1997,26(1):1-16
Transplantation of cellular components of the permissive peripheral nerve environment in some types of spinal cord injury holds great promise to support regrowth of axons through the site of injury. In the present study, Schwann cell grafts were positioned between transected stumps of adult rat thoracic spinal cord to test their efficacy to serve as bridges for axonal regeneration. Schwann cells were purified in culture from adult rat sciatic nerve, suspended in Matrigel:DMEM (30:70), and drawn into polymeric guidance channels 8mm long at a density of 120×106 cells ml-1. Adult Fischer rat spinal cords were transected at the T8 cord level and the next caudal segment was removed. Each cut stump was inserted 1mm into the channel. One month later, a bridge between the severed stumps had been formed, as determined by the gross and histological appearance and the ingrowth of propriospinal axons from both stumps. Propriospinal neurons (mean, 1064±145 SEM) situated as far away as levels C3 and S4 were labelled by retrograde tracing with Fast Blue injected into the bridge. Near the bridge midpoint there was a mean of 1990±594 myelinated axons and eight times as many nonmyelinated, ensheathed axons. Essentially no myelinated or unmyelinated axons were observed in control Matrigel-only grafts. Brainstem neurons were not retrogradely labelled from the graft, consistent with growth of immunoreactive serotonergic and noradrenergic axons only a short distance into the rostral end of the graft, not far enough to reach the tracer placed at the graft midpoint. Anterograde tracing with PHA-L introduced rostral to the graft demonstrated that axons extended the length of the graft but essentially did not leave the graft. This study demonstrates that Schwann cell grafts serve as bridges that support (1) regrowth of both ascending and descending axons across a gap in the adult rat spinal cord and (2) limited regrowth of serotonergic and noradrenergic fibres from the rostral stump. Regrowth of monoaminergic fibres into grafts was not seen in an earlier study of similar grafts placed inside distally capped rather than open-ended channels. Additional intervention will be required to foster growth of the regenerated axons from the graft into the distal cord tissue. 相似文献
745.
Cristiane Elizabeth Costa de Macêdo Veronique Van Sint Jan Jean-Marie Kinet Stanley Lutts 《Acta Physiologiae Plantarum》2009,31(6):1255-1262
The effects of Al2(SO4)3·18H2O on growth of root and apical root cells were studied in seedlings of rice cultivars differing in Al resistance including
I Kong Pao and Aiwu (Al-sensitive) and IRAT 112 and IR6023-10-1-1 (Al-resistant). Inhibition of root growth was a typical
effect of Al, and the extent of the inhibition depended on both cultivar and Al concentration. Al impaired the activity of
the root meristem as indicated by reductions in its size, mitotic activity and the diameter of the meristematic cell nucleoli.
Cell size in the elongation zone of the root was also reduced by Al. The reliability of the haematoxylin staining method to
classify rice cultivars according to their Al-sensitivity failed to discriminate the Al-resistant IR6023-10-1-1 cultivar from
the two sensitive cultivars. The results are discussed in relation to the Al resistance mechanisms operating in rice. 相似文献
746.
747.
M Dy B Lebel E Schneider F Arenzana-Seisdedos C Abbadi 《Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie》1985,300(14):513-518
Since homogeneously purified Interleukin 3 can induce an increase in histamine synthesis by normal bone marrow cells (HCSF activity), it has been suggested that HCSF and IL3 could be identical. In this paper, we show evidence that HCSF activity can be obtained without any IL3 activity (determined by the proliferation of an IL3-dependent cell line). This distinction has been achieved in two different ways: (a) the physico-chemical separation of HCSF and IL3 from crude secondary MLC supernatants and (b) the spontaneous production by the P388D1 cell line of a factor possessing all the characteristics of HCSF without any IL3 activity. In addition, preliminary results show that anti-IL3 antibodies do not inhibit the increase in histamine synthesis induced by HCSF while it strongly diminishes that induced by IL3. 相似文献
748.
749.
B. Kenneth Koe Lorraine A. Lebel Carol B. Fox John E. Macor 《Journal of neurochemistry》1992,58(4):1268-1276
Abstract: 3-(1,2,5,6-Tetrahydro-4-pyridyl)-5- n -propoxyindole (CP-96,501) was found to be a more selective ligand at the serotonin 5-HT1B receptor than the commonly used 5-HT1B agonist, 3-(1,2,5,6-tetrahydro-4-pyridyl)-5-methoxyindole (RU 24969). In rat brain membranes, the tritiated derivative, [3 H]CP-96,501, was found to bind with a high affinity ( K D , 0.21 n M ) to a single binding site ( n H , 1.0). The receptor density of this site ( B max , 72 fmol/mg of protein) matched that of the 5-HT1B receptor determined with [3 H]5-HT. Competition curves of 16 serotonergic compounds in [3 H]CP-96,501 binding also indicated a single binding site. The rank order of their binding affinities with this new radioligand showed a high degree of correlation with their affinities at the 5-HT1B receptor determined with [3 H]5-HT or [125 I]iodocyanopindolol. Serotonergic compounds displayed competitive inhibition of [3 H]CP-96,501 binding. In the presence of 5'-guanylylimidodiphosphate [Gpp(NH)p], [3 H]CP-96,501 binding was reduced, while the potency of CP-96,501 to displace [125 I]iodocyanopindolol binding was also decreased. These findings are consistent with the agonist nature of CP-96,501. The results of this study suggest that [3 H]CP-96,501 is a useful agonist radioligand for the 5-HT1B receptor. 相似文献
750.
In response to T cell mitogens, spleen cells produce a large amount of histamine, whereas no or a slight increase is observed after B cell mitogen stimulation. This increased histamine production results from the effect of a factor having all the characteristics of HCSF (histamine-producing cell-stimulating factor) already described in secondary MLC supernatant. This factor is produced by Thy-1, 2, Lyt-1, 2-positive cells. Spleen cell cultures derived from skin-allografted mice during rejection produce more histamine in response to T cell mitogens than do spleen cells from normal or syngeneic grafted mice. Such a phenomenon is not observed in response to B cell mitogens. A striking association is found between enhanced histamine synthesis and skin allograft rejection. This phenomenon results from a) a five to 10-fold increase in HCSF production by allograft recipient spleen cells in response to T cell mitogens, and b) an increase in HCSF sensitivity of these spleen cells. 相似文献