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931.
932.
Spike trains from neurons are often used to make inferences about the underlying processes that generate the spikes. Random
walks or diffusions are commonly used to model these processes; in such models, a spike corresponds to the first passage of
the diffusion to a boundary, or firing threshold. An important first step in such a study is to fit families of densities
to the trains' interspike interval histograms; the estimated parameters, and the families' goodness of fit can then provide
information about the process leading to the spikes. In this paper, we propose the generalized inverse Gaussian family because
its members arise as first passage time distributions of certain diffusions to a constant boundary. We provide some theoretical
support for the use of these diffusions in neural firing models. We compare this family with the lognormal family, using spike
trains from retinal ganglion cells of goldfish, and simulations from an integrate-and-fire and a dynamical model for generating
spikes. We show that the generalized inverse Gaussian family is closer to the true model in all these cases.
Received: 16 September 1996 / Accepted in revised form: 2 July 1997 相似文献
933.
934.
Females of the moth Utetheisa ornatrix (family Arctiidae) mate preferentially with larger males. As a consequence, females have larger sons and daughters, which have been shown to be more acceptable in courtship and more fecund, respectively. We demonstrate that mating with larger males results in accelerated oviposition by the female on the day after mating and that females are intrinsically prone to lay larger eggs in the first days after mating. Both these additional size-dependent effects have potential adaptive consequences. 相似文献
935.
K.V. Venkatesh 《Process Biochemistry》1997,32(8):651-655
A detailed metabolic flux analysis for lactic acid production by Streptococcus lactis has been carried out. A metabolic reaction set was constructed for the metabolism of S. lactis. Fluxes through these reactions were estimated by using accumulation rates of biomass, product and consumption rates of the substrate, which were obtained through experiments. The changes in the flux movement are shown for different pHs and initial lactate concentrations of the medium. The analysis indicated that pH only affected the uptake rates of lactose, whereas lactate ion concentration influenced the movement of flux through the network. 相似文献