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Kazuko Ôba Naoko Makimoto Tsukaho Hattori Ikuzo Uritani 《Bioscience, biotechnology, and biochemistry》2013,77(7):1929-1931
We determined the effects of yolk water-soluble protein (YSP) on bone resorption. YSP potently suppressed osteoclastogenesis from bone marrow-derived precursor cells driven by tumor necrosis factor-α (TNF-α). YSP (200 μg/ml) abolished the formation of tartarate-resistant acid phosphatase (TRAP)-positive osteoclasts. Furthermore, TNF-α induced TRAP activity was greatly inhibited by YSP (100 μg/ml) treatment. Our results suggest that YSP has therapeutic potential for bone-erosive diseases. 相似文献
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A Putative Receptor Protein Kinase Gene in Ipomoea trifida 总被引:4,自引:0,他引:4
Kowyama Yasuo; Kakeda Katsuyuki; Kondo Katsuhiko; Imada Takahiro; Hattori Tsukaho 《Plant & cell physiology》1996,37(5):681-685
We have characterized a cDNA clone, IRK1, for a putative receptorkinase from a stigma cDNA library of Ipomoea trifida. IRK1 proteincontains an extracellular receptor-like domain and the consensussequences diagnostic of serine/threonine protein kinase. Boththe pattern of gene expression and the results of RFLP analysisindicate that the IRK1 gene is not primarily involved in theself-incompatibility system of Ipomoea. (Received October 16, 1995; Accepted April 10, 1996) 相似文献
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Shozo Ohta Tsukaho Hattori Atsushi Morikami Kenzo Nakamura 《Molecular & general genetics : MGG》1991,225(3):369-378
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Miyoshi Kazumaru; Nakata Eijiro; Nagato Yasuo; Hattori Tsukaho 《Plant & cell physiology》1999,40(4):443-447
The spatial and temporal expression patterns of three ABA-regulatedgenes of rice in the developing seeds of wild type and embryonicmutants were studied by in situ hybridization. By the use ofan embryo-less mutant, we found that the expression of thesegenes in the aleurone layers was independent of embryonic tissues. (Received August 24, 1998; Accepted January 23, 1999) 相似文献
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Plasticity of root growth in response to environmental cues and stresses is a fundamental characteristic of plants, in accordance with their sessile lifestyle. This is linked to the balance between plasticity and rigidity of cells in the root apex, and thus is coordinated with the control of cell wall properties. However, mechanisms underlying such harmonization are not well understood, in particular under stressful conditions. We have recently demonstrated that RICE SALT SENSITIVE3 (RSS3), a nuclear factor that mediates restrictive expression of jasmonate-induced genes, plays an important role in root elongation under saline conditions. In this study, we report that loss-of-function of RSS3 results in changes in cell wall properties such as lignin deposition and sensitivity to a cellulose synthase inhibitor, concomitant with altered expression of genes involved in cell wall metabolism. Based on these and previous phenotypic observations of the rss3 mutant, we propose that RSS3 plays a role in the coordinated control of root elongation and cell wall plasticity in the root apex. 相似文献