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Alex L. Sumich Toshiko Matsudaira Bryony Heasman Rachel V. Gow Almira Ibrahimovic Kebreab Ghebremeskel Michael A. Crawford Eric Taylor 《Prostaglandins, leukotrienes, and essential fatty acids》2013,88(6):431-436
Atypical fatty acid metabolism has been reported in attention deficit hyperactivity disorder (ADHD), however, its relationship with temperament in this population is unclear. The current study investigated the association between blood levels of fatty acids implicated in brain structure and function (omega-3, omega-6, omega-9) and personality traits of stability (neuroticism, conscientiousness and agreeableness) and plasticity (extraversion and openness). Twenty right-handed adolescent boys with ADHD completed a self-report NEO-FFI personality questionnaire, and had fatty acid content assessed from red blood using gas chromatography. Pearson's correlations showed no significant associations between omega-3 levels and personality. After correction for multiple comparisons, Adrenic Acid (C22:4n6) was inversely associated with stability. Oleic acid (C18:1n9) was positively associated with plasticity. Results are in line with a role of fatty acids in brain function. They suggest that those fatty acids that are involved in myelination (Adrenic, Oleic) have the strongest associations with temperament in adolescents with ADHD. 相似文献
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Shunji Takahashi Wai-Cheung Yip Toshiko Matsugami Goro Tamura 《Journal of plant research》1996,109(4):363-368
The ferredoxin-sulfite reductase (Fd-SiR; hydrogen-sulfide: ferredoxin oxidoreductase, EC 1.8.7.1) activities of shoot and
root of leek (Allium tuberosum) were increased by sulfate limitation in the early stage of growth. Western blot analysis demonstrated an increased amount
of SiRs in root under sulfate limitation, suggesting that SiRs were derepressed. The derepression was observed in shoot when
1.5 mM nitrate was supplied to the plants under sulfate limitation, and clearly in root when 15 mM nitrate was supplied under
sulfate limitation. When nitrate was absent from the nutrient solution, the SiR activity in both tissues was very low. Combined
with the results of the sulfate- or nitrate-limitation experiments, it is suggested that the degree of the derepression of
SiR in both tissue under sulfate limitation is affected by the concentration of nitrate, and further that the mechanism of
regulation of the SiR activity is different in each tissue. The decreases in the ratios of the total SiR activities (shoot/root)
in the latter stage of seedling growth indicate that root play a very important role in sulfate assimilation. 相似文献