排序方式: 共有48条查询结果,搜索用时 0 毫秒
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Andres Gomez Jessica M Rothman Klara Petrzelkova Carl J Yeoman Klara Vlckova Juan D Uma?a Monica Carr David Modry Angelique Todd Manolito Torralba Karen E Nelson Rebecca M Stumpf Brenda A Wilson Ran Blekhman Bryan A White Steven R Leigh 《The ISME journal》2016,10(2):514-526
Although the critical role that our gastrointestinal microbes play in host physiology is now well established, we know little about the factors that influenced the evolution of primate gut microbiomes. To further understand current gut microbiome configurations and diet–microbe co-metabolic fingerprints in primates, from an evolutionary perspective, we characterized fecal bacterial communities and metabolomic profiles in 228 fecal samples of lowland and mountain gorillas (G. g. gorilla and G. b. beringei, respectively), our closest evolutionary relatives after chimpanzees. Our results demonstrate that the gut microbiomes and metabolomes of these two species exhibit significantly different patterns. This is supported by increased abundance of metabolites and bacterial taxa associated with fiber metabolism in mountain gorillas, and enrichment of markers associated with simple sugar, lipid and sterol turnover in the lowland species. However, longitudinal sampling shows that both species'' microbiomes and metabolomes converge when hosts face similar dietary constraints, associated with low fruit availability in their habitats. By showing differences and convergence of diet–microbe co-metabolic fingerprints in two geographically isolated primate species, under specific dietary stimuli, we suggest that dietary constraints triggered during their adaptive radiation were potential factors behind the species-specific microbiome patterns observed in primates today. 相似文献
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Gut microbiome composition and metabolomic profiles of wild western lowland gorillas (Gorilla gorilla gorilla) reflect host ecology 下载免费PDF全文
Andres Gomez Klara Petrzelkova Carl J. Yeoman Klara Vlckova Jakub Mrázek Ingrid Koppova Franck Carbonero Alexander Ulanov David Modry Angelique Todd Manolito Torralba Karen E. Nelson H. Rex Gaskins Brenda Wilson Rebecca M. Stumpf Bryan A. White Steven R. Leigh 《Molecular ecology》2015,24(10):2551-2565
The metabolic activities of gut microbes significantly influence host physiology; thus, characterizing the forces that modulate this micro‐ecosystem is key to understanding mammalian biology and fitness. To investigate the gut microbiome of wild primates and determine how these microbial communities respond to the host's external environment, we characterized faecal bacterial communities and, for the first time, gut metabolomes of four wild lowland gorilla groups in the Dzanga‐Sangha Protected Areas, Central African Republic. Results show that geographical range may be an important modulator of the gut microbiomes and metabolomes of these gorilla groups. Distinctions seemed to relate to feeding behaviour, implying energy harvest through increased fruit consumption or fermentation of highly fibrous foods. These observations were supported by differential abundance of metabolites and bacterial taxa associated with the metabolism of cellulose, phenolics, organic acids, simple sugars, lipids and sterols between gorillas occupying different geographical ranges. Additionally, the gut microbiomes of a gorilla group under increased anthropogenic pressure could always be distinguished from that of all other groups. By characterizing the interplay between environment, behaviour, diet and symbiotic gut microbes, we present an alternative perspective on primate ecology and on the forces that shape the gut microbiomes of wild primates from an evolutionary context. 相似文献
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Cuív PÓ Klaassens ES Durkin AS Harkins DM Foster L McCorrison J Torralba M Nelson KE Morrison M 《Journal of bacteriology》2011,193(15):4025-4026
Although Bacteroides vulgatus is one of the most prevalent microorganisms in the human gastrointestinal tract, little is known about the genetic potential of this species. Here, we describe the annotated draft genome sequence of B. vulgatus PC510 isolated from human feces. 相似文献
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Jose Mar��a Gil-S��nchez Manuel Moral Jos�� Bueno Javier Rodr��guez-Siles Santiago Lillo Joaqu��n P��rez Jose Manuel Mart��n Gerardo Valenzuela Germ��n Garrote Bernado Torralba Miguel ��ngel Sim��n-Mata 《European Journal of Wildlife Research》2011,57(6):1203-1211
The use of non-invasive long-term monitoring data to estimate home ranges of the critically endangered Iberian lynx has been evaluated. This programme began in 2002 and consisting of both annual latrine and camera-trap surveys, with the aims of detecting and individually identifying the maximum number of individuals and delineating female home range boundaries. Radio-tracking data were used to evaluate the accuracy of home range estimates constructed with camera-trapping data. There was little overlap of camera-trapping home ranges (7.0%?±?1.47), which suggests the existence of real territories consistent with the land tenure system expected for the species. Camera trapping home range estimates were half the size of radio-tracking data (54.1%?±?6.0 of overlapping). When comparing core areas, only the radio-tracking data did not yield improved results (36.7?±?5.4 of overlapping). Estimation of territories, which escaped detection each year, ranged from 0.0% to 5.7%. The results produced by camera-trapping data in this non-intrusive monitoring programme could be considered precise, and are therefore well suited to provide the knowledge required for appropriate conservation of this endangered species. 相似文献
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Cuív PÓ Klaassens ES Durkin AS Harkins DM Foster L McCorrison J Torralba M Nelson KE Morrison M 《Journal of bacteriology》2011,193(5):1288-1289
While the microbiota resident in the human gut is now known to provide a range of functions relevant to host health, many of the microbial members of the community have not yet been cultured or are represented by a limited number of isolates. We describe here the draft genome sequence of Turicibacter sanguinis PC909, isolated from a pooled healthy human fecal sample as part of the Australian Human Gut Microbiome Project. 相似文献
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Katherine R Amato Carl J Yeoman Angela Kent Nicoletta Righini Franck Carbonero Alejandro Estrada H Rex Gaskins Rebecca M Stumpf Suleyman Yildirim Manolito Torralba Marcus Gillis Brenda A Wilson Karen E Nelson Bryan A White Steven R Leigh 《The ISME journal》2013,7(7):1344-1353
The gastrointestinal (GI) microbiome contributes significantly to host nutrition and health. However, relationships involving GI microbes, their hosts and host macrohabitats remain to be established. Here, we define clear patterns of variation in the GI microbiomes of six groups of Mexican black howler monkeys (Alouatta pigra) occupying a gradation of habitats including a continuous evergreen rainforest, an evergreen rainforest fragment, a continuous semi-deciduous forest and captivity. High throughput microbial 16S ribosomal RNA gene sequencing indicated that diversity, richness and composition of howler GI microbiomes varied with host habitat in relation to diet. Howlers occupying suboptimal habitats consumed less diverse diets and correspondingly had less diverse gut microbiomes. Quantitative real-time PCR also revealed a reduction in the number of genes related to butyrate production and hydrogen metabolism in the microbiomes of howlers occupying suboptimal habitats, which may impact host health. 相似文献