全文获取类型
收费全文 | 2712篇 |
免费 | 221篇 |
国内免费 | 2篇 |
出版年
2024年 | 5篇 |
2023年 | 25篇 |
2022年 | 35篇 |
2021年 | 95篇 |
2020年 | 45篇 |
2019年 | 69篇 |
2018年 | 79篇 |
2017年 | 69篇 |
2016年 | 72篇 |
2015年 | 135篇 |
2014年 | 155篇 |
2013年 | 169篇 |
2012年 | 252篇 |
2011年 | 252篇 |
2010年 | 138篇 |
2009年 | 116篇 |
2008年 | 146篇 |
2007年 | 136篇 |
2006年 | 105篇 |
2005年 | 113篇 |
2004年 | 110篇 |
2003年 | 82篇 |
2002年 | 72篇 |
2001年 | 69篇 |
2000年 | 55篇 |
1999年 | 55篇 |
1998年 | 25篇 |
1997年 | 17篇 |
1996年 | 8篇 |
1995年 | 11篇 |
1994年 | 12篇 |
1993年 | 14篇 |
1992年 | 17篇 |
1991年 | 14篇 |
1990年 | 16篇 |
1989年 | 22篇 |
1988年 | 12篇 |
1987年 | 11篇 |
1986年 | 12篇 |
1985年 | 10篇 |
1984年 | 6篇 |
1983年 | 11篇 |
1981年 | 6篇 |
1980年 | 5篇 |
1979年 | 5篇 |
1978年 | 4篇 |
1976年 | 5篇 |
1973年 | 4篇 |
1970年 | 4篇 |
1969年 | 5篇 |
排序方式: 共有2935条查询结果,搜索用时 15 毫秒
41.
42.
43.
Hien Van Doan Seyed Hossein Hoseinifar Wanaporn Tapingkae Mintra Seel-audom Sanchai Jaturasitha Mahmoud A. O. Dawood Sutee Wongmaneeprateep Tran Thi Nang Thu Maria ngeles Esteban 《Probiotics and antimicrobial proteins》2020,12(2):400-411
The present work, herein, studied the effects of corncob-derived xylooligosaccharides (CDXOS) and Lactobacillus plantarum CR1T5 (LP) integrated into fish d 相似文献
44.
45.
A new temperate wood bamboo endemic to Vietnam is described and illustrated as Chimonocalamus bidoupensis N.H.Nghia & V.T.Tran. The new species is similar to C. baviensis in general appearance, but differs by its densely ciliate culms, culm sheaths that are concave at the apex with dense, white hairs on the abaxial surface of the sheath, and perfect florets 7–8 mm long. 相似文献
46.
Porshakov A. M. Korneev M. G. Chumachkova E. A. Chau Nguyen Van Toan Thinh Van Cuong Vo Viet 《Entomological Review》2021,101(9):1287-1292
Entomological Review - Analysis of the literature data has shown that the present day flea fauna of mammals in Vietnam is represented by 50 flea species. In 2019–2020, we surveyed seven... 相似文献
47.
48.
49.
Sarah Findakly Vikas Daggubati Galo Garcia III Sydney A. LaStella Abrar Choudhury Cecilia Tran Amy Li Pakteema Tong Jason Q. Garcia Natasha Puri Jeremy F. Reiter Libin Xu David R. Raleigh 《The Journal of cell biology》2021,220(1)
Vertebrate Hedgehog signals are transduced through the primary cilium, a specialized lipid microdomain that is required for Smoothened activation. Cilia-associated sterol and oxysterol lipids bind to Smoothened to activate the Hedgehog pathway, but how ciliary lipids are regulated is incompletely understood. Here we identified DHCR7, an enzyme that produces cholesterol, activates the Hedgehog pathway, and localizes near the ciliary base. We found that Hedgehog stimulation negatively regulates DHCR7 activity and removes DHCR7 from the ciliary microenvironment, suggesting that DHCR7 primes cilia for Hedgehog pathway activation. In contrast, we found that Hedgehog stimulation positively regulates the oxysterol synthase CYP7A1, which accumulates near the ciliary base and produces oxysterols that promote Hedgehog signaling in response to pathway activation. Our results reveal that enzymes involved in lipid biosynthesis in the ciliary microenvironment promote Hedgehog signaling, shedding light on how ciliary lipids are established and regulated to transduce Hedgehog signals. 相似文献
50.
Mark Kittisopikul Takeshi Shimi Meltem Tatli Joseph Riley Tran Yixian Zheng Ohad Medalia Khuloud Jaqaman Stephen A. Adam Robert D. Goldman 《The Journal of cell biology》2021,220(4)
Nuclear lamin isoforms form fibrous meshworks associated with nuclear pore complexes (NPCs). Using datasets prepared from subpixel and segmentation analyses of 3D–structured illumination microscopy images of WT and lamin isoform knockout mouse embryo fibroblasts, we determined with high precision the spatial association of NPCs with specific lamin isoform fibers. These relationships are retained in the enlarged lamin meshworks of Lmna−/− and Lmnb1−/− fibroblast nuclei. Cryo-ET observations reveal that the lamin filaments composing the fibers contact the nucleoplasmic ring of NPCs. Knockdown of the ring-associated nucleoporin ELYS induces NPC clusters that exclude lamin A/C fibers but include LB1 and LB2 fibers. Knockdown of the nucleoporin TPR or NUP153 alters the arrangement of lamin fibers and NPCs. Evidence that the number of NPCs is regulated by specific lamin isoforms is presented. Overall the results demonstrate that lamin isoforms and nucleoporins act together to maintain the normal organization of lamin meshworks and NPCs within the nuclear envelope. 相似文献