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991.
Tibor Benedek M. D. 《Mycopathologia》1951,6(2):108-115
Summary 1. The so-called macroconidia observed onMicrosporum-infected hairs in vivo is an animal cell and not of vegetable origin.2. The cells described as macroconidia in the parasitic stage of the genusMicrosporum are typical cells of Henle's layer of the internal root sheath of the hair.3. Whether these spurious macroconidia can be seen in a preparation or not depends entirely on the mode of epilation.4. The cells of Henle's layer can be easily differentiated from true macroconidia by a number of criteria, such as refractivity, staining properties, cultural characteristics, comparative measurements and last but not least, they have no connections with any mycelial elements.5.Sabouraud correctly recognized these spurious macroconidia as epithelial cells.6. One of the basic laws of mycological observation that dermatophytes do not produce any organs of fructification in their parasitic life cycle, remains unchanged.(After a demonstration given at the Meeting of the Chicago Medical Mycological Society, February 28, 1951) 相似文献
992.
P. K. Wallace Tibor Keler Paul M. Guyre Michael W. Fanger 《Cancer immunology, immunotherapy : CII》1997,45(3-4):137-141
Splenectomy and corticosteroids are the treatment of choice for patients with immune thrombocytopenic purpura (ITP). However,
for the 10%–15% of patients who do not respond to conventional therapy, high-dose i.v. IgG can induce life-saving transient
responses. The benefits of i.v. IgG have been attributed to Fc receptor blockade; however, the involvement of the individual
Fc receptors for IgG (FcγR) in ITP remain to be more completely defined. Recently a mAb, designated mAb H22, which recognizes
an epitope on FcγRI (CD64) outside the ligand-binding domain, was humanized. Because mAb H22 is a human IgG1 and FcγRI has
a high affinity for human IgG1 antibodies, we predicted that mAb H22 would bind to the FcγRI ligand-binding site through its
Fc domain and to its external FcγRI epitope through both Fab domains. These studies demonstrate that mAb H22 blocked FcγRI-mediated
phagocytosis of opsonized red blood cells more effectively than an irrelevant IgG. Moreover, cross-linking FcγRI with mAb
H22 down-modulated FcγRI expression on monocytes, an effect seen within 2 h.
Accepted: 14 October 1997 相似文献
993.
Nam Michael Tran-Cong Attila Mándi Sándor Balázs Király Tibor Kurtán Wenhan Lin Zhen Liu Peter Proksch 《Chirality》2020,32(5):605-610
The endophytic fungus Coniothyrium sp. was isolated from leaves of Quercus robur. Fermentation of this fungus on solid rice medium yielded two new furoic acid derivatives ( 1 and 2 ) and two additional known compounds. The structures of the new compounds were determined by extensive analysis of 1D and 2D nuclear magnetic resonance spectra as well as high-resolution mass spectrometry data. Compound 1 , containing three aromatic chromophores attached by rotatable sigma bonds and a chirality center in benzylic position, was found to be a scalemic mixture with an excess of the (S) enantiomer, the absolute configuration of which was elucidated as by the solution time-dependent density functional theory-electronic circular dichroism approach. The ωB97X/TZVP PCM/MeCN and SOGGA11-X/TZVP SMD/MeCN methods were used for geometry reoptimization to reproduce the solution conformational ensemble. All isolated compounds were tested for their cytotoxicity but proved to be inactive. 相似文献
994.
995.
996.
The aim of this paper is to address the question of how informationtransfer affects foraging efficiency in a colonial breedingsituation. By creating computer simulations, we attempt to modelinformation transfer of food location by individuals withinthe colony. Three kinds of foraging strategy were modeled: searchernoinformation transfer (solo foraging), watcherlimitedinformation transfer (local enhancement), and a mixture of watcherand followerfull information transfer (information center).The predictability of food was changed by varying patchiness(ratio of food patches) and duration of food patches. When thefood occurs in many randomly distributed patches and the fooddensity in each is low, the solitary searcher strategy givesthe best foraging efficiency. The significance of informationtransfer strategies and colonial breeding on foraging efficiencyincrease when food becomes more clumped. The solitary watcherstrategy is the best at intermediately clumped food distribution.Colonial breeding gives the best foraging efficiency when theinformation center operates and there are some high-densityfood patches. 相似文献
997.
Tibor Bakács Pál Czanik Ian Kimber Gábor Ringwald Michael Moore Erzsébet Ábrahám 《Cancer immunology, immunotherapy : CII》1984,16(3):170-174
We have analysed the influence of human malignant, inflammatory and infectious disease on the capacity of peripheral lymphocytes to mediate antibody-dependent haemolysis. The application of an enzyme-like kinetic model for measurement of maximal cytotoxic function has permitted reproducible and sensitive determinations of the K-cell function. The results show that malignant disease is associated with enhancement of ADCC capacity. 相似文献
998.
999.
András Kosztolányi Nikoletta Nagy Tibor Kovács Zoltán Barta 《Entomological Science》2015,18(2):292-294
Although intensive care for offspring by both parents is rare in arthropods, it occurs in some species including the beetle Lethrus apterus. According to previous publications, in this species the male collects leaves, which are used by the female to form balls in the underground nest burrow. These balls serve as food for the hatched offspring. Most knowledge about the behavior of this species is based on information collected more than a century ago. Therefore, we investigated above‐ground breeding behavior and the status of nest burrows of this beetle in its natural habitat in Hungary. Our results suggest that contrary to previously documented cases, above‐ground parental care, i.e. the collection of leaves, is done predominantly not by the males but the females. Further research is needed to understand the role of the sexes in parental care in this species and to explain the discrepancy between the previously documented cases and the results we report here. 相似文献