全文获取类型
收费全文 | 965篇 |
免费 | 62篇 |
专业分类
1027篇 |
出版年
2023年 | 15篇 |
2022年 | 17篇 |
2021年 | 49篇 |
2020年 | 29篇 |
2019年 | 56篇 |
2018年 | 47篇 |
2017年 | 36篇 |
2016年 | 54篇 |
2015年 | 72篇 |
2014年 | 77篇 |
2013年 | 95篇 |
2012年 | 91篇 |
2011年 | 115篇 |
2010年 | 69篇 |
2009年 | 40篇 |
2008年 | 34篇 |
2007年 | 23篇 |
2006年 | 35篇 |
2005年 | 24篇 |
2004年 | 24篇 |
2003年 | 10篇 |
2002年 | 9篇 |
2001年 | 2篇 |
2000年 | 1篇 |
1998年 | 1篇 |
1996年 | 1篇 |
1993年 | 1篇 |
排序方式: 共有1027条查询结果,搜索用时 0 毫秒
61.
Pablo A. P. Antiqueira Paula M. de Omena Thiago Gonalves-Souza Camila Vieira Gustavo H. Migliorini Mnica F. Kersch-Becker Tiago N. Bernab Ftima C. Recalde Sandra Benavides- Gordillo Gustavo Q. Romero 《Oecologia》2020,192(3):745-753
Biotic and abiotic factors may individually or interactively disrupt plant–pollinator interactions, influencing plant fitness. Although variations in temperature and precipitation are expected to modify the overall impact of predators on plant–pollinator interactions, few empirical studies have assessed if these weather conditions influence anti-predator behaviors and how this context-dependent response may cascade down to plant fitness. To answer this question, we manipulated predation risk (using artificial spiders) in different years to investigate how natural variation in temperature and precipitation may affect diversity (richness and composition) and behavioral (visitation) responses of flower-visiting insects to predation risk, and how these effects influence plant fitness. Our findings indicate that predation risk and an increase in precipitation independently reduced plant fitness (i.e., seed set) by decreasing flower visitation. Predation risk reduced pollinator visitation and richness, and altered species composition of pollinators. Additionally, an increase in precipitation was associated with lower flower visitation and pollinator richness but did not alter pollinator species composition. However, maximum daily temperature did not affect any component of the pollinator assemblage or plant fitness. Our results indicate that biotic and abiotic drivers have different impacts on pollinator behavior and diversity with consequences for plant fitness components. Even small variation in precipitation conditions promotes complex and substantial cascading effects on plants by affecting both pollinator communities and the outcome of plant–pollinator interactions. Tropical communities are expected to be highly susceptible to climatic changes, and these changes may have drastic consequences for biotic interactions in the tropics. 相似文献
62.
Magnetic resonance analysis of the effects of acute ammonia intoxication on rat brain. Role of NMDA receptors 总被引:2,自引:0,他引:2
Cauli O López-Larrubia P Rodrigues TB Cerdán S Felipo V 《Journal of neurochemistry》2007,103(4):1334-1343
Acute ammonia intoxication leads to rapid death, which is prevented by blocking N -methyl- d -aspartate (NMDA) receptors. The subsequent mechanisms leading to death remain unclear. Brain edema seems an important step. The aim of this work was to study the effects of acute ammonia intoxication on different cerebral parameters in vivo using magnetic resonance and to assess which effects are mediated by NMDA receptors activation. To assess edema induction, we injected rats with ammonium acetate and measured apparent diffusion coefficient (ADC) in 16 brain areas. We also analyzed the effects on T1, T2, and T2* maps and whether these effects are prevented by blocking NMDA receptors. The effects of acute ammonia intoxication are different in different brain areas. T1 relaxation time is reduced in eight areas. T2 relaxation time is reduced only in ventral thalamus and globus pallidus. ADC values increased in hippocampus, caudate-putamen, substantia nigra and cerebellar cortex, reflecting vasogenic edema. ADC decreased in hypothalamus, reflecting cytotoxic edema. Myo-inositol increased in cerebellum and substantia nigra, reflecting vasogenic edema. N -acetyl-aspartate decreased in cerebellum, reflecting neuronal damage. Changes in N -acetyl-aspartate, T1 and T2 are prevented by blocking NMDA receptors with MK-801 while changes in ADC or myo-inositol (induction of edema) are not. 相似文献
63.
St Martin JL Klucken J Outeiro TF Nguyen P Keller-McGandy C Cantuti-Castelvetri I Grammatopoulos TN Standaert DG Hyman BT McLean PJ 《Journal of neurochemistry》2007,100(6):1449-1457
Several transgenic mouse lines with altered alpha-synuclein expression have been developed that show a variety of Parkinson's disease-like symptoms without specific loss of dopaminergic neurons. Targeted over-expression of human alpha-synuclein using viral-vector mediated gene delivery into the substantia nigra of rats and non-human primates leads to dopaminergic cell loss and the formation of alpha-synuclein aggregates reminiscent of Lewy bodies. In the context of these recent findings, we used adeno-associated virus (AAV) to over-express wild type human alpha-synuclein in the substantia nigra of mice. We hypothesized that this over-expression would recapitulate pathological hallmarks of Parkinson's disease, creating a mouse model to further characterize the disease pathogenesis. Recombinant AAV expressing alpha-synuclein was stereotaxically injected into the substantia nigra of mice, leading to a 25% reduction of dopaminergic neurons after 24 weeks of transduction. Furthermore, examination of mRNA levels of stress-related proteins using laser capture microdissection and quantitative PCR revealed a positive correlation of Hsp27 expression with the extent of viral transduction at 4 weeks and a positive correlation of Hsp40, Hsp70 and caspase 9 with the extent of viral transduction at 24 weeks. Taken together, our findings suggest that targeted over-expression of alpha-synuclein can induce pathology at the gross anatomical and molecular level in the substantia nigra, providing a mouse model in which upstream changes in Parkinson's disease pathogenesis can be further elucidated. 相似文献
64.
65.
Pereira L Gonçalves J Franco-Duarte R Silva J Rocha T Arnold C Richards M Macaulay V 《Molecular biology and evolution》2007,24(3):868-874
The first complete mitochondrial DNA (mtDNA) sequences (approximately 16,569 bp) in 20 patients with asthenozoospermia and a comparison with 23 new complete mtDNA sequences in teratoasthenozoospermic individuals, confirmed no sharing of specific polymorphisms or specific mitochondrial lineages between these individuals. This is strong evidence against the accepted claim of a major role played by mtDNA in male fertility, once supported by haplogroup association studies based on the screening of hypervariable region I. The hypothesis of maternally driven selection acting in male reproductive success must thus be treated with caution. 相似文献
66.
67.
Jesus Ronald Ferreira Santos Ana Nunes Nandyara Bianca dos Santos Jeannie Nascimento Melo Francisco Tiago Vasconcelos 《Systematic parasitology》2022,99(6):761-769
Systematic Parasitology - Nematodes collected from the stomach and large intestine of Rhinoclemmys punctularia (Daudin) from the eastern Amazon, Brazil, are assigned to a new genus, Vogtnema n.... 相似文献
68.
69.
70.