Degradation ofn-alkane-1-sulfonates byPseudomonas

We have isolated two strains ofPseudomonas, AJ 1 and AJ 2, growing on the C₄–C₇ and the C₈–C₁₂ n-alkane-1-sulfonates, respectively, as the only source of their carbon and energy. The alkane sulfonates are dissimilated by these strains, ultimately to yield carbon dioxide, water and sulfate. In the primary oxidation reaction(s) the corresponding fatty acid and sulfate are formed. The fatty acid is subsequently degraded by Β-oxidation. For strain AJ 1, growing on the lower alkane sulfonates, we could exclude various pathways of degradation which might have been present in addition to the one mentioned above.     

Molecular aspects of sex determination in mice: an alternative model for the origin of the Sxr region

Using a combination of in situ mapping and DNA analysis with recombinant DNA probes specific for the Sxr region of the mouse Y chromosome, we show that both the gene(s) controlling primary sex determination and the expression of the male-specific antigen H-Y (Tdy and Hya respectively) are located on the minute short arm of the mouse Y chromosome. We demonstrate that the H-Y- variant of Sxr (Sxr') arose by a partial deletion within the Sxr region and propose an alternative model for the generation of the original Sxr region.