全文获取类型
收费全文 | 646篇 |
免费 | 49篇 |
国内免费 | 1篇 |
专业分类
696篇 |
出版年
2022年 | 5篇 |
2021年 | 10篇 |
2020年 | 7篇 |
2019年 | 5篇 |
2018年 | 17篇 |
2017年 | 13篇 |
2016年 | 9篇 |
2015年 | 24篇 |
2014年 | 29篇 |
2013年 | 30篇 |
2012年 | 54篇 |
2011年 | 36篇 |
2010年 | 23篇 |
2009年 | 21篇 |
2008年 | 36篇 |
2007年 | 34篇 |
2006年 | 33篇 |
2005年 | 24篇 |
2004年 | 22篇 |
2003年 | 22篇 |
2002年 | 22篇 |
2001年 | 30篇 |
2000年 | 16篇 |
1999年 | 21篇 |
1998年 | 15篇 |
1997年 | 7篇 |
1996年 | 8篇 |
1995年 | 12篇 |
1994年 | 7篇 |
1993年 | 9篇 |
1992年 | 7篇 |
1991年 | 6篇 |
1990年 | 9篇 |
1989年 | 7篇 |
1988年 | 7篇 |
1987年 | 5篇 |
1986年 | 5篇 |
1985年 | 5篇 |
1984年 | 9篇 |
1982年 | 3篇 |
1981年 | 4篇 |
1979年 | 4篇 |
1978年 | 2篇 |
1977年 | 3篇 |
1976年 | 2篇 |
1975年 | 2篇 |
1970年 | 3篇 |
1967年 | 2篇 |
1966年 | 2篇 |
1965年 | 2篇 |
排序方式: 共有696条查询结果,搜索用时 0 毫秒
681.
Ordered hexagonal arrays of parallel collagen fibers produce the brilliant green structural color of the fleshy, supraorbital caruncles of male Velvet Asity (Philepitta castanea; Aves: Eurylaimidae). The collagen arrays are organized in larger macrofibrils that are packed irregularly within cone-shaped papillae that cover the surface of the caruncle. The color of the caruncle conforms closely to the wavelengths predicted by applying Bragg's Law of constructive reflection to measurements of the size and spatial organization of the collagen arrays. These observations constitute a novel mechanism of structural color production in animals. These collagen arrays are convergently similar to the smaller, highly structured collagen arrays in the mammalian cornea, which exploit the same physical mechanism to produce optical transparency. © 1994 Wiley-Liss, Inc. 相似文献
682.
683.
Nicole L. W. Van Hal G. A. M. S. Van Dongen C. B. M. Ten Brink Jim N. Herron Gordon B. Snow R. H. Brakenhoff 《Cancer immunology, immunotherapy : CII》1997,45(2):88-92
Monoclonal antibody (mAb) U36 was developed for the treatment of minimal residual disease of head and neck squamous cell
carcinoma (HNSCC). The mAb-U36-defined antigen was characterized by cDNA cloning, and was shown to be identical to the keratinocyte-specific
CD44 splice variant epican. The epitope recognized by mAb U36 was shown to be located in the v6 domain. Two amino acids within
the epitope appeared to differ from the sequences that have been described in literature. The sequence of the epitope appeared
to contain glutamic acid at position 367 and lysine at position 374, while valine and arginine respectively have been described
before. Interestingly, another anti-CD44v6 antibody with possible clinical application, VFF18, recognizes an epitope in the
same area. With respect to the applicability of these antibodies for tumor targeting, this variation might have an influence
on antibody-antigen interaction and mAb accumulation in the tumor. Furthermore, this observation raised the question whether
the different epitopes are related to the malignant behavior of tumor cells. In this paper we determine the relative affinity
of mAb U36 for the variant epitope sequences by tumor cell binding assays using synthetic peptides for competition. The presence
of glutamic acid instead of valine at position 367 caused strong competition. Further evaluation showed that the published
valine variant does not exist in vivo, and is the result of a sequencing artefact. The effect of substitution of lysine for
arginine at position 374 had no effect on the binding of mAb U36 to the cells. This amino acid variation was shown to be due
to allelic polymorphism. There was no trend towards allelic imbalance in tumor cells as compared to normal cells.
Received: 5 June 1997 / Accepted: 14 August 1997 相似文献
684.
Iu V Ten V V Shafranov V A Repalov V A Kozhevnikov V N Mazokhin 《Biulleten' eksperimental'no? biologii i meditsiny》1988,105(1):25-27
It has been established that heat conductivity was markedly increased after UHF-irradiation. The combined use of UHF-irradiation and cryogenic destruction is 30-40 times as effective as cryogenic destruction alone. 相似文献
685.
686.
687.
Background
Pelodera (Rhabditis) strongyloides is a small saprophytic nematode that lives in decaying organic matter. On rare occasions, it can invade the mammalian skin, causing a pruritic, erythematous, alopecic and crusting dermatitis on skin sites that come into contact with the ground. Diagnosis of the disease is based on case history (a dog living outdoors on damp straw bedding) with characteristic skin lesions and on the demonstration of typical larvae in skin scrapings or biopsy. Pelodera (rhabditic) dermatitis cases have been reported mainly from Central European countries and the United States. 相似文献688.
689.
690.