Antiviral and Antimicrobial Nucleoside Derivatives: Structural Features and Mechanisms of Action

Molecular Biology - The emergence of new viruses and resistant strains of pathogenic microorganisms has become a powerful stimulus in the search for new drugs. Nucleosides are a promising class of...     

Sarcocystis neurona Transmission from Opossums to Marine Mammals in the Pacific Northwest

EcoHealth - Increasing reports of marine mammal deaths have been attributed to the parasite Sarcocystis neurona. Infected opossums, the only known definitive hosts, shed S. neurona sporocysts in...     

Contribution of P2X4 receptor in pain associated with rheumatoid arthritis: a review

Purinergic Signalling - Pain is the most common symptom reported by patients with rheumatoid arthritis (RA) even after the resolution of chronic joint inflammation. It is believed that...     

Antagonism of the ATP-gated P2X7 receptor: a potential therapeutic strategy for cancer

Purinergic Signalling - The P2X receptor 7 (P2X7R) is a plasma membrane receptor sensing extracellular ATP associated with a wide variety of cellular functions. It is most commonly expressed on...     

Dreissenids’ breaking loose: differential attachment as a possible driver of the dominance shift between two invasive mussel species

Biological Invasions - Ponto-Caspian dreissenids are notorious freshwater invaders. Recently, widespread observations show a dominance shift from the early invader, Dreissena polymorpha, to its...     

Features of the Radial and Axial Distributions of the Toroidal Magnetic Field in the Axial Jet Ejection at the PF-3 Facility

Plasma Physics Reports - The results of experiments on the study of the features of the dynamics and internal structure of the axial plasma ejection at the PF-3 facility carried out within the...