全文获取类型
收费全文 | 169篇 |
免费 | 1篇 |
出版年
2022年 | 2篇 |
2020年 | 4篇 |
2019年 | 3篇 |
2018年 | 7篇 |
2017年 | 3篇 |
2016年 | 7篇 |
2015年 | 3篇 |
2014年 | 7篇 |
2013年 | 4篇 |
2012年 | 11篇 |
2011年 | 4篇 |
2010年 | 8篇 |
2009年 | 5篇 |
2008年 | 12篇 |
2007年 | 7篇 |
2006年 | 4篇 |
2005年 | 5篇 |
2004年 | 8篇 |
2003年 | 1篇 |
2002年 | 3篇 |
2001年 | 2篇 |
2000年 | 2篇 |
1999年 | 4篇 |
1998年 | 1篇 |
1997年 | 2篇 |
1992年 | 7篇 |
1991年 | 2篇 |
1990年 | 3篇 |
1989年 | 6篇 |
1988年 | 1篇 |
1987年 | 2篇 |
1986年 | 1篇 |
1985年 | 5篇 |
1978年 | 1篇 |
1977年 | 2篇 |
1975年 | 3篇 |
1974年 | 4篇 |
1973年 | 1篇 |
1972年 | 1篇 |
1971年 | 2篇 |
1970年 | 3篇 |
1969年 | 2篇 |
1968年 | 2篇 |
1967年 | 1篇 |
1965年 | 2篇 |
排序方式: 共有170条查询结果,搜索用时 0 毫秒
91.
We studied the effects of maternal stress (the so-called prenatal stress, PS, provided by immobilization of pregnant female
Wistar rats for 1 h daily during the 15–21st gestational days) on the corticosterone response in the blood plasma evoked by
infusion of 10 μg noradrenaline bitartrate into the III cerebral ventricle or by injection of β-1-24-corticotropin in 3-month-old
male and female offspring. The animals were bearing an intracerebroventricular stainless steel guide cannula implanted eight
to nine days before the experiment, and a Silastic catheter inserted into the external jugular vein 24 h prior to the experiment.
Blood samples were periodically taken from conscious unrestrained rats (before and then 30, 60 and 90 or 120 min after noradrenaline
or corticotropin challenge). In the male offspring PS augmented and prolonged an increase in the plasma corticosterone level
resulting from adrenergic stimulation of the hypothalamus, as compared with that in non-stressed animals. In prenatally stressed
female offspring tested in diestrus, there was no response of the hypothalamic-pituitary-adrenal (HPA) axis to intracerebroventricular
noradrenaline stimulation, in contrast to what was observed in the control. Prenatal stress did not modify the adrenal cortex
responsiveness to corticotropin either in male or in female offspring. The results demonstrate differential effects of PS
on the adrenergic activation of the HPA axis in males and females. A decrease in the acute HPA stress-responsiveness in prenatally
stressed male rats, which was demonstrated in an earlier study, and the maintenance or even enhancement of this effect in
prenatally stressed females are not likely to be connected with the state of hypothalamic adrenergic reactivity. 相似文献
92.
93.
94.
T. P. Vavilova I. V. Tarasenko A. E. Medvedev I. G. Ostrovskaya 《Biochemistry (Moscow) Supplemental Series B: Biomedical Chemistry》2010,4(4):383-385
The content of basic fibroblast growth factor (bFGF) and also interleukins 1β and 6 (IL-1β and IL-6) has been investigated
in rat buccal mucosa after its surgical injury by an erbium laser (Er:YAG laser) and a scalpel. The laser emission caused
a sharp increase in the content of these regulators on the second day after treatment followed by decrease observed on the
seventh day. These results may reflect synergistic effect of these peptide regulators in the wound defect. Changes in time-course
of bFGF, IL-1β and IL-6 release in the wound formed by the laser beam compared with the wound induced by the cutting instrument
may promote earlier appearance of the proliferation phase. 相似文献
95.
T A Deviatkina L M Tarasenko V E Klusha O I Tsebrzhinski? R K Mutsenietse 《Biulleten' eksperimental'no? biologii i meditsiny》1989,107(6):673-675
The influence of peptide thymopentin on ulcer effects of the stomach mucous membrane in rats and the state of its processes in acute and chronic stress as well as their combination influence were investigated. The intercommunication of frequency of the formation of ulcer and the activity of superoxide dismutase in stomach fibers was established. Thymopentin displayed a marked antiulcerogenic effect in all kinds of stress. 相似文献
96.
97.
98.
K. K. Tarasenko 《Paleontological Journal》2014,48(5):551-562
Based on an almost complete skeleton (skull, scapula fragment, humerus, ulna, radius, 7 cervical, 12 thoracic, 17 lumbar and caudal vertebrae, sternum, and hyoid), a new cetotheriid, Zygiocetus nartorum gen. et sp. nov., is described. It comes from the Middle Sarmatian beds (Upper Miocene) of the Krasnooktyabr’sk Formation of the Polevoe 1 locality (Republic of Adygea). 相似文献
99.
Bacillus anthracis toxins may be attenuated if macrophages could neutralize toxins upon contact or exposure. Glycoconjugate-bearing polymers,
which have been shown to bind to Bacillus spores, were tested for recognition and binding of protective antigen (PA), lethal factor (LF), and edema factor (EF) toxins.
We have demonstrated modulation of macrophage activity following exposure to these toxins. Without glycoconjugate (GC) activation,
murine macrophages were killed by Bacillus toxins. GCs were shown to have a protective influence, sparing macrophages from toxin-induced cell death, as shown by increased
macrophage cell viability based on trypan blue assay. Increased levels of inducible nitric oxide (NO) production by macrophages
in presence of GCs suggest that GCs provide an activation signal for macrophages and stimulate their function. Results hint
to GCs that promote neutralization of Bacillus toxins, block toxin-induced macrophage death, while increasing macrophage activation. Polymeric GCs may suggest novel approaches
to improve existing or develop new vaccines as well as immunotherapeutics. 相似文献
100.