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排序方式: 共有275条查询结果,搜索用时 31 毫秒
31.
Hosoda A Nomura E Murakami A Koshimizu K Ohigashi H Mizuno K Taniguchi H 《Bioorganic & medicinal chemistry letters》2000,10(13):1439-1442
Ester compounds consisting of ferulic acid and myo-inositol, obtained from rice bran, were synthesized. The inhibitory effects of these feruloyl-myo-inositols on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced superoxide (O2-) generation were examined using differentiated HL-60 cells. Among the derivatives tested, only 3,4,5,6-tetra-O-acetyl-1,2-di-O-[3-(4'-acetoxy-3'-methoxyphenyl)-2-pr openoyl]-myo-inositol (3) showed a distinct inhibitory activity. 相似文献
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Tsuguo Sasaki Yuko Sasaki Toshiharu Matsumura Noriko Oyama Kaoru Koshimizu 《Microbiology and immunology》1989,33(5):423-427
A strain of Mycoplasma hominis lacking a major membrane protein of 120 kDa was isolated from a Vero cell culture. This strain showed very slow growth rate and formed nipple-less colonies on agar medium. 相似文献
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Hirai Nobuhiro; Yamamuro Munehiro; Koshimizu Koichi; Shinozaki Masateru; Takimoto Atsushi 《Plant & cell physiology》1994,35(4):691-695
Extracts from the cotyledons of seedlings of Pharbitis nil strainViolet cultured at low temperature, which inducestheir flowering even in continuous light, with or without precedentexposure to high-intensity light, which shortens the periodof low temperature required for flowering, were analyzed byHPLC for substances correlating with the flower-inducing process.The content of two phenylpropanoids were found to increase duringthe low-temperature, and were identified as 3-O-feruloylquinicacid and dehydrodiconiferyl alcohol-13-O-ß-D-glucoside.The increase was more rapid in the cotyledons exposed to high-intensitylight before the low-temperature. This suggests that the accumulationof these compounds is correlated to the promotive effect ofhigh-intensity light on the flower-induction by low temperature. (Received March 7, 1994; Accepted April 2, 1994) 相似文献
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Jun Sawai Kazushi Matsumoto Taka-aki Saito Yasuhiko Isomura Risei Wada 《International biodeterioration & biodegradation》2009,63(2):196-200
The influence of infrared (IR) radiation on the viability and heat-activation of Bacillus subtilis spores, suspended in phosphate-buffered saline, was investigated. Two types of IR heaters with different spectral distributions were used. Near-infrared (NIR) and far-infrared (FIR) heaters with main wavelengths of approximately 1 μm and 3–6 μm, respectively, were utilized. Although both irradiation treatments decreased the number of B. subtilis colonies at a bulk temperature of approximately 75 °C, the mode of action was clearly different. In the case of the NIR heater, the number of colony-counts decreased gradually. In contrast, use of the FIR heater resulted in heat activation of the spores during the early stage of irradiation at a low bulk temperature (40–60 °C) over several minutes, followed by a decrease in the number of colonies. Consequently, FIR irradiation inactivated 90% of B. subtilis spores more effectively as compared to NIR irradiation for 20 min with a suspension volume of 20 ml and irradiation energy of 7.57 kW m?2. Spore exposure to FIR irradiation accelerated their germination rate in nutrient broth; however, this was not true for treatment with the NIR heater. The absorption IR spectrum of B. subtilis spores indicated that FIR radiation was absorbed easily by the spore cell components and might activate the bioactive substances involved in germination. Even at the same irradiation energy, the influence of infrared radiation on spore germination was dependent on the IR spectral distribution. Bacterial spores undergoing germination lose their resistance to stressors, such as heat, chemicals and ultraviolet rays. FIR heating promotes heat activation and germination, thereby producing vegetative cells that are more susceptible to other killing methods, enabling the killing of bacterial spores at lower stress without product damage. 相似文献
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Yoshiki Aoshima Hiroyuki Sakakibara Taka-aki Suzuki Shunsuke Yamazaki Kayoko Shimoi 《Experimental Animals》2014,63(3):331-338
Recent studies have suggested the possibility that nocturnal light exposure affects many
biological processes in rodents, especially the circadian rhythm, an endogenous
oscillation of approximately 24 h. However, there is still insufficient information about
the physiological effects of nocturnal light exposure. In this study, we examined the
changes in gene expression and serum levels of plasminogen activator inhibitor-1 (PAI-1),
a major component of the fibrinolytic system that shows typical circadian rhythmicity, in
C3H/He mice. Zeitgeber time (ZT) was assessed with reference to the onset of light period
(ZT0). Exposure to fluorescent light (70 lux) for 1 h in the dark period (ZT14) caused a
significant increase in hepatic Pai-1 gene expression at ZT16. Serum
PAI-1 levels also tended to increase, albeit not significantly. Expression levels of the
typical clock genes Bmal1, Clock, and
Per1 were significantly increased at ZT21, ZT16, and ZT18,
respectively. Exposure to nocturnal light significantly increased plasma adrenalin levels.
The effects of nocturnal light exposure on Pai-1 expression disappeared
in adrenalectomized mice, although the changes in clock genes were still apparent. In
conclusion, our results suggest that nocturnal light exposure, even for 1 h, alters
hepatic Pai-1 gene expression by stimulating the adrenal pathway.
Adrenalin secreted from the adrenal gland may be an important signaling mediator of the
change in Pai-1 expression in response to nocturnal light exposure. 相似文献
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