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51.
S Tungpradabkul S Panyim P Wilairat Y Yuthavong 《Comparative biochemistry and physiology. B, Comparative biochemistry》1983,74(3):481-485
1. DNA from various rodent Plasmodium species and strains and from P. falciparum, the human parasite, were analysed by agarose gel electrophoresis following digestion with restriction endonucleases EcoRI, Hind III and Bam Hl. Complex patterns of ethidium-stained bands were obtained, which showed similarity but reproducible differences among the various parasite species (P. chabaudi, P. yoelii, P. berghei and P. falciparum). 2. No differences could be discerned among two cloned strains of P. yoelii (33X, and YM) and among pyrimethamine-resistant (pyrimethamine + chloroquine)-resistant and the drug-sensitive P. chabaudi clone from which the resistant clones were derived. 3. From the known complexity of Plasmodium DNA it could be concluded that the visible bands were derived from repetitive DNA fractions. 相似文献
52.
Suda Tunpiboonsak Rungrawee Mongkolrob Kaniskul Kitudomsub Phawatwaristh Thanwatanaying Witcha Kiettipirodom Yanin Tungboontina Sumalee Tungpradabkul 《Journal of microbiology (Seoul, Korea)》2010,48(1):63-70
Burkholderia pseudomallei, a motile and rod Gram-negative bacterium, is the causative agent of melioidosis. The bacterium is an intracellular pathogen
and that motility is generally crucial for their survival in a natural environment and for systemic infection inside a host.
We report here a role of B. pseudomallei polyphosphate kinase in virulence, such as an oxidative stress response, motilities and biofilm formation. The polyphosphate
kinase (ppk) mutant is susceptible to hydrogen peroxide in an oxidative stress condition, unable to perform swimming, swarming motilities,
and has lower density biofilm forming capacity than the wild-type strain. We also demonstrated that both polyphosphate kinase
and motile flagella are essential and independently involved in biofilm formation. The B. pseudomallei flagellin (fliC) mutant and B. mallei, a nonmotile species, are shown to produce higher density biofilm formation than the ppk mutant, but less than wild type B. pseudomallei. 相似文献