全文获取类型
收费全文 | 123篇 |
免费 | 6篇 |
出版年
2023年 | 2篇 |
2022年 | 1篇 |
2021年 | 1篇 |
2020年 | 3篇 |
2019年 | 5篇 |
2018年 | 2篇 |
2017年 | 1篇 |
2016年 | 7篇 |
2015年 | 6篇 |
2014年 | 9篇 |
2013年 | 12篇 |
2012年 | 15篇 |
2011年 | 7篇 |
2010年 | 9篇 |
2009年 | 4篇 |
2008年 | 5篇 |
2007年 | 9篇 |
2006年 | 3篇 |
2005年 | 6篇 |
2004年 | 4篇 |
2003年 | 2篇 |
2002年 | 4篇 |
2000年 | 1篇 |
1995年 | 1篇 |
1990年 | 1篇 |
1989年 | 2篇 |
1988年 | 3篇 |
1987年 | 1篇 |
1981年 | 1篇 |
1977年 | 1篇 |
1974年 | 1篇 |
排序方式: 共有129条查询结果,搜索用时 234 毫秒
121.
122.
Suhail Ahmad 《BMJ (Clinical research ed.)》1974,3(5932):657-659
The diuretic response to 20-mg and 40-mg oral doses of frusemide was significantly smaller in a group of epileptic patients on chronic anticonvulsant therapy than in a group of normal staff members. Furthermore, the peak response was considerably delayed in the epileptic patients. The difference in the volume of diuresis was maintained after intravenous injection of 20 mg of frusemide. It is suggested that the sensitivity of the renal tubule to the diuretic action of frusemide is reduced by anticonvulsant therapy and that there may also be delayed absorption of the drug from the gastrointestinal tract. 相似文献
123.
124.
Boulila Moncef ElSayed Abdelaleim Ismail Rafudeen Mohammed Suhail Omar Ahmad Alsayed 《Molecular biology reports》2020,47(3):1625-1636
Molecular Biology Reports - A total of 53 plant species accessions from different geographic regions, including four melatonin precursor-coding genes obtained from Arachis hypogaea (ASMT1, 2, 3 and... 相似文献
125.
Pothiappan Kumarasamy Manickam Sasipriya Viswambaram Ganapiriya Kannayiram Muthukumaravel Kumara Perumal Pradhoshini Munawar Suhail Ahmed Mohamed Saiyad Musthafa Caterina Faggio 《Acta zoologica》2023,104(3):398-406
Sesarmid crab, Muradium tetragonum, considered a key detritus consumer plays a significant role in the nutrient cycling and energy flow in most of the mangrove environments. Morphological and ultrastructural organization of the M. tetragonum male reproductive system are characterized through transmission electron microscopic studies. Adult males (3.2–4.2 cm) with dark violet carapace and white-tipped cheliped were procured alongside the coastal areas of Tanjavur district, Tamil Nadu, India. The morphological analysis highlights the male gonads to be bilaterally symmetrical and anterolaterally located inside the cephalothorax. A pair of elongated testes lying attached to the hypodermis of the carapace leads to a long highly coiled vas deferens categorized into three distinct regions (Proximal vas deferens, Middle vas deferens and distal vas deferens) structurally and functionally with Posterior vas deferens receiving sac-like accessory glands. It gets followed by an ejaculatory duct and ends with the penile papillae at the coxae's base of the fifth peripod. Structural modifications were observed in the ultrastructure of vas deferens envisage (considering) its functional role in storing spermatophores, active absorption and assisting the secretory activity. Spermatophores, witnessed as spherical bodies are bounded by a dense double wall. Aflagellate, immotile and spherical spermatozoa that measuring 3.6 μm in diameter encompasses a complex acrosome cupped by a nucleus. Moreover, perforatorium and the extending nuclear arms with chromatin, as displayed in the experimental organism M. tetragonum, are in synergy with that of certain brachyurans as specified in the study. Hence, the current study assessing the morphology and ultrastructure parameters of the male gonads could be useful in understanding the physiology of sexual maturation, annual cyclic changes, tracing the phylogenetic relationship among species and enhancing the brood-stock management. 相似文献
126.
Nida Suhail Nayeem Bilal Shirin Hasan Ausaf Ahmad Ghulam Md. Ashraf Naheed Banu 《Cell stress & chaperones》2015,20(6):1023-1036
Social stressors evolving from individual and population interactions produce stress reactions in many organisms (including humans), influencing homeostasis, altering the activity of the immunological system, and thus leading to various pathological states including cancer and their progression. The present study sought to validate the effectiveness of chronic unpredictable stress (CUS) in cancer promotion and to assess oxidative stress outcomes in terms of various in vivo biochemical parameters, oxidative stress markers, DNA damage, and the development of skin tumors in Swiss albino mice. Animals were randomized into different groups based on their exposure to CUS alone, 7,12-dimethylbenz(a)anthracene (DMBA) alone (topical), and DMBA-12-O-tetradecanoylphorbol-13-acetate (TPA) (topical) and exposure to CUS prior to DMBA or DMBA-TPA treatments and sacrificed after 16 weeks of treatment. Prior exposure to CUS significantly increased the pro-oxidant effect of carcinogen, depicted by compromised levels of antioxidants in the circulation and skin, accompanied by enhanced lipid peroxidation, plasma corticosterone, and marker enzymes as compared to DMBA-alone or DMBA-TPA treatments. DNA damage results corroborated the above biochemical outcomes. Also, the development of skin tumors (in terms of their incidence, tumor yield, and tumor burden) in mice in the presence and absence of stress further strongly supported our above biochemical measurements. CUS may work as a promoter of carcinogenesis by enhancing the pro-oxidant potential of carcinogens. Further studies may be aimed at the development of interventions for disease prevention by identifying the relations between psychological factors and DNA damage. 相似文献
127.
128.
Ghulam Md Ashraf Sabika Rizvi Shoa Naqvi Nida Suhail Nayeem Bilal Shirin Hasan Mohammad Tabish Naheed Banu 《Amino acids》2010,39(5):1321-1332
A soluble β-galactoside-binding lectin was purified by gel filtration chromatography from Bubalus bubalis heart. Its metal-independent nature, molecular weight of 14.5 kDa, preferential affinity for β-d-lactose, and 87–92% identity with carbohydrate recognition domain of previously reported galectin-1 confirmed its inclusion
in galectin-1 subfamily. Stokes radii determination using gel filtration under reducing and non-reducing conditions revealed
its homo-dimeric nature, further confirming its Gal-1 nomenclature. The purified lectin was found to be the most stable mammalian
heart galectin purified till date, suggesting its preferential use in various recognition studies. Treatment of the purified
lectin with oxidizing agent, thiol blocking reagents, denaturants, and detergents resulted in significant changes in UV–VIS,
fluorescence, CD and FTIR spectra, which strongly emphasized the important aspect of regular secondary structure of galectins
for the maintenance of their active conformation. Reduction of the activity of the purified lectin after oxidation by H2O2, with remarkable fluorescence quenching, may suggest potential role for galectin-1 in free radical-induced, oxidative stress-mediated
cardiovascular disorders. The predictions of bioinformatics studies were found to be in accordance with the results obtained
in wet lab. 相似文献
129.
Yadav Radha Vij Rishika Kapila Suman Khan Suhail H. Kumar Naveen Meena Sunita Kapila Rajeev 《Annals of microbiology》2019,69(5):483-494
The current study was intended to investigate the cholesterol-lowering potential of the two Lactobacillus rhamnosus probiotic strains, LR 5957 and LR 5897, isolated from ‘dahi’. Cholesterol-lowering ability of both strains was determined in in vitro conditions. For in vivo investigations, the Wistar rats were randomly assigned into five groups and treated with different diets: standard diet (SD), high-cholesterol diet (HCD), HCD with Milk, HCD with LR 5957–fermented milk, and HCD with LR 5897–fermented milk. After 3 months of feeding, different parameters of hypercholesterolemia were measured in blood, feces, liver, and kidney. Both the strains, LR 5957 and LR 5897, showed the ability to grow in the presence of cholesterol and eliminate the cholesterol under in vitro conditions. In vivo results indicate that consumption of probiotic-fermented milk has significantly reduced the HCD-induced body weight, hyperlipidemia, and hepatic lipids (total cholesterol and triacylglycerol). Further, increased cholesterol excretion in feces was also observed in probiotic-fed groups. The studied fermented milk also helped to maintain healthy liver and kidney by increasing the antioxidant activities and decreasing the lipid peroxidation. Consumption of probiotic-fermented milk also found to decrease the mRNA expression of the inflammatory markers TNF-α and IL-6 in the liver. Overall, our results indicate that the L. rhamnosus strains, LR 5957 and LR 5897, are two potential probiotic strains that can ameliorate the diet-induced hypercholesterolemia. 相似文献