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81.
82.
Schistocerca gregaria sometimes refuse to lay eggs into the “old sand” that is kept in their cages for several days. We investigated why they rejected the old sand for oviposition. Locusts exclusively laid eggs into new sand when presented together with old sand, indicating that the old sand contained an oviposition-inhibiting (OI) factor. We examined whether this factor was derived from locust feces or fed grass (Bromus catharticus). Locusts laid all eggs into the sand with grass when presented together with sand containing feces. In contrast, few eggs were laid into the sand with grass when clean sand was offered at the same time, suggesting that the OI factor originated from the grass and was concentrated in the feces. The OI factor was efficiently extracted from feces with water compared with ethanol and acetone. OI activity was detected by extraction of feces with water for 1 min, although a longer extraction time yielded higher activity. The water extract of feces retained OI activity after boiling. None of the eggs which were buried in sand containing fecal extract hatched, whereas most of the eggs buried in clean sand or sand containing grass extract hatched, showing a correlation between OI activity and a lethal effect on eggs. 相似文献
83.
Effects of lactoferrin and lactoperoxidase‐containing food on the oral microbiota of older individuals
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Manabu Nakano Hiroyuki Wakabayashi Hirosuke Sugahara Toshitaka Odamaki Koji Yamauchi Fumiaki Abe Jin‐Zhong Xiao Kohji Murakami Kentaro Ishikawa Shouji Hironaka 《Microbiology and immunology》2017,61(10):416-426
84.
Pseudocapacitors: Enhanced Li‐Ion Accessibility in MXene Titanium Carbide by Steric Chloride Termination (Adv. Energy Mater. 9/2017)
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85.
Sugahara H Kondo T Okada M Ikeda Y Kaida K Fudou R Mizuno T Sakagami Y 《Bioscience, biotechnology, and biochemistry》2008,72(10):2521-2525
A two-component system (TCS) comprising a histidine kinase (HK) sensor and a response regulator (RR) plays important roles in regulating the virulence of many pathogenic bacteria. We used a new screening method to isolate novel inhibitor Art1 against bacterial sensory HK from an acetone extract of solid cultures of Articulospora sp., an aquatic hypomycete. Art1 inhibited the ATP-dependent autophosphorylation of recombinant glutathione S-transferase-fusion protein SasA, a cyanobacterial HK, with an IC50 value of 9.5 microg/ml. 相似文献
86.
Yamauchi S Masuda T Sugahara T Kawaguchi Y Ohuchi M Someya T Akiyama J Tominaga S Yamawaki M Kishida T Akiyama K Maruyama M 《Bioscience, biotechnology, and biochemistry》2008,72(11):2981-2986
The antioxidant activity of butane-type lignans was evaluated. Secoisolariciresinol (SECO) and dihydroguaiaretic acid (DGA) showed higher radical scavenging activity than that of 7,7'-dioxodihydroguaiaretic acid (ODGA). SECO and DGA inhibited the oxidation of unsaturated fatty acid. Both enantiomers of DGA were also lipoxygenase inhibitors, but neither enantiomer of SECO inhibited the lipoxygenase activity. 相似文献
87.
Novel oligosaccharide has suppressive activity against human leukemia cell proliferation 总被引:1,自引:0,他引:1
Hosomi O Misawa Y Takeya A Matahira Y Sugahara K Kubohara Y Yamakura F Kudo S 《Glycoconjugate journal》2009,26(2):189-198
Various oligosaccharides containing galactose(s) and one glucosamine (or N-acetylglucosamine) residues with β1–4, α1–6 and β1–6 glycosidic bond were synthesized; Galβ1–4GlcNH2, Galα1–6GlcNH2, Galα1–6GlcNAc, Galβ1–6GlcNH2, Galβ1–4Galβ1–4GlcNH2 and Galβ1–4Galβ1–4GlcNAc. Galα1–6GlcNH2 (MelNH2) and glucosamine (GlcNH2) had a suppressive effect on the proliferation of K562 cells, but none of the other saccharides tested containing GlcNAc
showed this effect. On the other hand, the proliferation of the human normal umbilical cord fibroblast was suppressed by none
of the saccharides other than GlcNH2. Adding Galα1–6GlcNH2 or glucosamine to the culture of K562 cell, the cell number decreased strikingly after 72 h. Staining the remaining cells
with Cellstain Hoechst 33258, chromatin aggregation was found in many cells, indicating the occurrence of cell death. Furthermore,
all of the cells were stained with Galα1–6GlcNH-FITC (MelNH-FITC). Neither the control cells nor the cells incubated with
glucosamine were stained. On the other hand, when GlcNH-FITC was also added to cell cultures, some of them incubated with
Galα1–6GlcNH2 were stained. The difference in the stainability of the K562 cells by Galα1–6GlcNH-FITC and GlcNH-FITC suggests that the
intake of Galα1–6GlcNH2 and the cell death induced by this saccharide is not same as those of glucosamine. The isolation of the Galα1–6GlcNH2 binding protein was performed by affinity chromatography (melibiose-agarose) and LC-MS/MS, and we identified the human heterogeneous
ribonucleoprotein (hnRNP) A1 (34.3 kDa) isoform protein (30.8 kDa). The hnRNP A1 protein was also detected from the eluate(s)
of the MelNH-agarose column by the immunological method (anti-hnRNP-A1 and HRP-labeled anti-mouse IgG (γ) antibodies). 相似文献
88.
A novel alternative splicing isoform of human T-cell leukemia virus type 1 bZIP factor (HBZ-SI) targets distinct subnuclear localization 总被引:4,自引:0,他引:4
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89.
90.
Taishi Hashiguchi Takanari Kobayashi Duriya Fongmoon Ajaya Kumar Shetty Shuji Mizumoto Nobuyuki Miyamoto Toshikazu Nakamura Shuhei Yamada Kazuyuki Sugahara 《Biochimica et Biophysica Acta (BBA)/General Subjects》2011