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991.
Clinton N. Jenkins Nathan J. Sanders Alan N. Andersen Xavier Arnan Carsten A. Brühl Xim Cerda Aaron M. Ellison Brian L. Fisher Matthew C. Fitzpatrick Nicholas J. Gotelli Aaron D. Gove Benoit Guénard John E. Lattke Jean‐Philippe Lessard Terrence P. McGlynn Sean B. Menke Catherine L. Parr Stacy M. Philpott Heraldo L. Vasconcelos Michael D. Weiser Robert R. Dunn 《Diversity & distributions》2011,17(4):652-662
Aim To use a fine‐grained global model of ant diversity to identify the limits of our knowledge of diversity in the context of climate change. Location Global. Methods We applied generalized linear modelling to a global database of local ant assemblages to predict the species density of ants globally. Predictors evaluated included simple climate variables, combined temperature × precipitation variables, biogeographic region, elevation, and interactions between select variables. Areas of the planet identified as beyond the reliable prediction ability of the model were those having climatic conditions more extreme than what was represented in the ant database. Results Temperature was the most important single predictor of ant species density, and a mix of climatic variables, biogeographic region and interactions between climate and region yielded the best overall model. Broadly, geographic patterns of ant diversity match those of other taxa, with high species density in the wet tropics and in some, but not all, parts of the dry tropics. Uncertainty in model predictions appears to derive from the low amount of standardized sampling of ants in Asia, in Africa and in the most extreme (e.g. hottest) climates. Model residuals increase as a function of temperature. This suggests that our understanding of the drivers of ant diversity at high temperatures is incomplete, especially in hot and arid climates. In other words, our ignorance of how ant diversity relates to environment is greatest in those regions where most species occur – hot climates, both wet and dry. Main conclusions Our results have two important implications. First, temperature is necessary, but not sufficient, to explain fully the patterns of ant diversity. Second, our ability to predict ant diversity is weakest exactly where we need to know the most, the warmest regions of a warming world. This includes significant parts of the tropics and some of the most biologically diverse areas in the world. 相似文献
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Stacy A. Krueger-Hadfield Sarah J. Shainker-Connelly Roseanna M. Crowell Morgan L. Vis 《Journal of phycology》2024,60(1):15-25
The relative frequency of sexual versus asexual reproduction governs the distribution of genetic diversity within and among populations. Most studies on the consequences of reproductive variation focus on the mating system (i.e., selfing vs. outcrossing) of diploid-dominant taxa (e.g., angiosperms), often ignoring asexual reproduction. Although reproductive systems are hypothesized to be correlated with life-cycle types, variation in the relative rates of sexual and asexual reproduction remains poorly characterized across eukaryotes. This is particularly true among the three major lineages of macroalgae (green, brown, and red). The Rhodophyta are particularly interesting, as many taxa have complex haploid–diploid life cycles that influence genetic structure. Though most marine reds have separate sexes, we show that freshwater red macroalgae exhibit patterns of switching between monoicy and dioicy in sister taxa that rival those recently shown in brown macroalgae and in angiosperms. We advocate for the investigation of reproductive system evolution using freshwater reds, as this will expand the life-cycle types for which these data exist, enabling comparative analyses broadly across eukaryotes. Unlike their marine cousins, species in the Batrachospermales have macroscopic gametophytes attached to filamentous, often microscopic sporophytes. While asexual reproduction through monospores may occur in all freshwater reds, the Compsopogonales are thought to be exclusively asexual. Understanding the evolutionary consequences of selfing and asexual reproduction will aid in our understanding of the evolutionary ecology of all algae and of eukaryotic evolution generally. 相似文献
995.
Microbiologists often describe communication as occurring within and between bacterial species and even across the prokaryote-eukaryote divide. In a strictly evolutionary sense, however, communication should occur only rarely between unrelated organisms. Clearly, the microbiological and evolutionary definitions and standards for what qualifies as communication widely differ. In microbiology, the term "communication" is often used to denote any interaction between two organisms. Advancement in knowledge hinges on precise language and conceptual distinctions when introducing new scientific ideas. While terminology exists for describing interactions which are not true communication, excessive preoccupation with semantics may impede progress. Umbrella terms such as 'communication' are useful, but additional insight can be gained by understanding the fitness consequences and adaptive significance of behaviors observed in multispecies communities. 相似文献
996.
Nearly one million deaths are attributed to malaria every year. Recent reports of multi-drug treatment failure of falciparum malaria underscore the need to understand the molecular basis of drug resistance. Multiple mutations in the Plasmodium falciparum chloroquine resistance transporter (pfcrt) are involved in chloroquine resistance, but the evolution of complex haplotypes is not yet well understood. Using over 4,500 archival human serum specimens collected from 19 Pacific populations between 1959 and 1979, the period including and just prior to the appearance of chloroquine treatment failure in the Pacific, we PCR-amplified and sequenced a portion of the pfcrt exon 2 from 771 P. falciparum-infected individuals to explore the spatial and temporal variation in falciparum malaria prevalence and the evolution of chloroquine resistance. In the Pacific, the prevalence of P. falciparum varied considerably across ecological zones. On the island of New Guinea, the decreases in prevalence of P. falciparum in coastal, high-transmission areas over time were contrasted by the increase in prevalence during the same period in the highlands, where transmission was intermittent. We found 78 unique pfcrt haplotypes consisting of 34 amino acid substitutions and 28 synonymous mutations. More importantly, two pfcrt mutations (N75D and K76T) implicated in chloroquine resistance were present in parasites from New Hebrides (now Vanuatu) eight years before the first report of treatment failure. Our results also revealed unexpectedly high levels of genetic diversity in pfcrt exon 2 prior to the historical chloroquine resistance selective sweep, particularly in areas where disease burden was relatively low. In the Pacific, parasite genetic isolation, as well as host acquired immune status and genetic resistance to malaria, were important contributors to the evolution of chloroquine resistance in P. falciparum. 相似文献
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Background
Countrywide 5.9 million, 0-11 Month old children are immunized annually by EPI (Expended Program on Immunization) against 8 vaccine preventable diseases including measles and so on. Unfortunately the basic immunity centers are not uniform throughout the country. Each center provides services to about 27000 people which is inadequate. The purpose of this study was to explore the development of EPI Pakistan in terms of immunization of measles.Methods
Nucleotide sequences were analyzed by neighbor joining method (bootstrap test) using Bio- edit and MEGA-5 software to find evolutionary relationship between wild type measles strain and vaccine strain (Edmonston strain) used in Pakistan. For statistical analysis of data SPSS 16 was used.Results
Currently 1.3 vaccinators are working at each U C (union council) which according to national EPI policy should be at least 2. About 56% and 44% children of age 0-11 months did not received second dose of measles in the last two years respectively. Out of these 4231 cases which were reported last year, 1370 have received their first dose of measles vaccine.Conclusion
Seroconversion and seroprevalence study of the vaccine and field strain of measles virus is needed to confirm whether its failure is due to service unavailability or vaccine in-affectivity. 相似文献999.
Atmospheric carbon dioxide (CO2) and global mean temperature are expected to be significantly higher by the end of the 21st century. Elevated CO2 (eCO2) and higher temperature each affect plant physiology and growth, but their interactive effects have not been reviewed statistically
with respect to higher chronic mean temperatures and abrupt heat stress. In this meta-analysis, we examined the effect of
CO2 on the physiology and growth of plants subjected to different temperature treatments. The CO2 treatments were categorized into ambient (<400 ppm) or elevated (>560 ppm) levels, while temperature treatments were categorized
into ambient temperature (AT), elevated temperature (ET; AT + 1.4–6°C), or heat stress (HS; AT + >8°C). Plant species were
grouped according to photosynthetic pathways (C3, C4), functional types (legumes, non-legumes), growth forms (herbaceous, woody), and economic purposes (crop, non-crop). eCO2 enhanced net photosynthesis at AT, ET, and HS in C3 species (especially at the HS level), but in C4 species, it had no effect at AT, a positive effect at ET, and a negative effect at HS. The positive effect of eCO2 on net photosynthesis was greater for legumes than for non-legumes at HS, for non-crops than crops at ET, and for woody than
herbaceous species at ET and HS. Total (W
T) and above- (W
AG) and below-ground (W
BG) biomass were increased by eCO2 for most species groups at all temperatures, except for C4 species and W
BG of legumes at HS. Hence, eCO2 × heat effects on growth were often not explained by effects on net photosynthesis. Overall, the results show that eCO2 effects on plant physiology and growth vary under different temperature regimes, among functional groups and photosynthetic
pathways, and among response variables. These findings have important implications for biomass accumulation and ecosystem
functioning in the future when the CO2 level is higher and climate extremes, such as heat waves, become more frequent. 相似文献
1000.
Stacy R. Hagemeier Elizabeth A. Barlow Qiao Meng Shannon C. Kenney 《Journal of virology》2012,86(24):13360-13370
The Epstein-Barr virus (EBV) latent-to-lytic switch is mediated by the viral proteins BZLF1 (Z), BRLF1 (R), and BRRF1 (Na). Since we previously showed that DNA-damaging agents (including chemotherapy and irradiation) can induce EBV lytic reactivation and recently demonstrated that wild-type p53 contributes to lytic reactivation, we investigated the role of the ATM kinase during EBV reactivation. ATM phosphorylates and activates p53, as well as numerous other substrates involved in the cellular DNA damage response. Using an ATM inhibitor (KU55933), we found that ATM activity is required for efficient induction of EBV lytic gene expression by a variety of different stimuli, including a histone deacetylase (HDAC) inhibitor, the transforming growth factor β (TGF-β) cytokine, a demethylating agent (5-azacytidine), B cell receptor engagement with anti-IgG antibody, hydrogen peroxide, and the proteosome inhibitor bortezomib. In EBV-infected AGS (gastric) cells, knockdown of ATM, or p53, expression inhibits EBV reactivation. Conversely, treatment of these cells with nutlin-3 (which activates p53 and ATM) robustly induces lytic reactivation in a p53- and ATM-dependent manner. The ability of the EBV R and Na proteins to induce lytic reactivation in EBV-infected AGS cells is ATM dependent. However, overexpression of Z induces lytic gene expression in the presence or absence of ATM activity. Our results suggest that ATM enhances Z promoter activity in the context of the intact EBV genome and that p53 contributes to the ATM effect. Nevertheless, since we found that ATM inhibitors also reduce lytic reactivation in Burkitt lymphoma cells that have no p53, additional ATM substrates must also contribute to the ATM effect. 相似文献