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951.
Jingwen Li Xi Long Qing Zhang Xi Fang Na Li Zhicheng Lin Jinghong Li Nian Xiong 《PLoS neglected tropical diseases》2020,14(12)
Medical staff treating Coronavirus Disease 2019 (COVID-19) patients are at high risk for exposure to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), and many have been infected, which may cause panic among medical workers, their relatives, health professionals, and government leaders. We report the epidemiologic and clinical characteristics of healthcare workers and that the majority of infected medical staff had milder symptoms/conditions with a better prognosis than admitted patients. Timely improvement to medical staff’s working conditions such as allowing adequate rest and providing sufficient medical protection is extremely important. 相似文献
952.
Yaowen Zhang Di Long Jiawen Wang Qiqin Li Zhongwen Wang Wei Lin Gaoqing Yuan 《Journal of Phytopathology》2020,168(7-8):451-459
Sterculia lanceolata, an important tropical woody plant, has high ornamental and medicinal value. To our knowledge, only brown root disease in this plant has been reported. In Nanning, Guangxi, China, an outbreak of leaf blight disease was observed on S. lanceolata in June 2019, with the leaf infection rate ranging from 80% to 100%. The disease seriously affected the leaves of trees and caused economic loss. Eight isolates were recovered from the infected leaves of different trees, and the pathogenicity was then determined by the methods of mycelial disc and conidial suspension, fulfilling Koch's postulates. According to the morphological and molecular biological characteristics of isolates, the pathogen causing leaf blight on S. lanceolata was identified as Colletotrichum siamense. Accurate identification of the pathogen provides a reliable basis for the control of the disease. 相似文献
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In recent years, the role of sphingolipids in pathogenic fungi, in terms of pathogenicity and resistance to azole drugs, has been a rapidly growing field. This review describes evidence about the roles of sphingolipids in azole resistance and fungal virulence. Sphingolipids can serve as signaling molecules that contribute to azole resistance through modulation of the expression of drug efflux pumps. They also contribute to azole resistance by participating in various microbial pathways such as the unfolded protein response (UPR), pH-responsive Rim pathway, and pleiotropic drug resistance (PDR) pathway. In addition, sphingolipid signaling and eisosomes also coordinately regulate sphingolipid biosynthesis in response to azole-induced membrane stress. Sphingolipids are important for fungal virulence, playing roles during growth in hosts under stressful conditions, maintenance of cell wall integrity, biofilm formation, and production of various virulence factors. Finally, we discuss the possibility of exploiting fungal sphingolipids for the development of new therapeutic strategies to treat infections caused by pathogenic fungi. 相似文献
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Co‐Co3O4/carbon nanotube/carbon foam (Co‐Co3O4/CNT/CF) nanocomposites were prepared by soaking melamine foam into a solution of Co(NO3)2·6H2O, followed by calcination in N2 and air in sequence. The obtained Co‐Co3O4/CNT/CF nanocomposites were characterized with scanning electron microscopy and cyclic voltammetry. It was found that Co3O4 nanoparticles were grown on the external of CF successfully, while CNTs were grown on the surfaces of CF in a large amount, which further improved the electrical conductivity of the. The prepared Co‐Co3O4/CNT/CF nanocomposites were then used to construct nonenzymatic sensor to detect glucose in alkaline solution. The sensor showed detection range from 1.2 μM to 2.29 mM with a detection limit of 0.4 μM (S/N =3) and a high sensitivity of 637.5 μA?1 cm?2. The developed sensor also showed an instant response, favorable reproducibility, and high selectivity. The results attest that Co‐Co3O4/CNT/CF composites have great potential in the development of nonenzymatic sensors for glucose. 相似文献