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Long-term treatment with angiotensin-converting enzyme inhibitors reduces post-infarction morbidity and mortality in patients
with left ventricular (LV) systolic dysfunction or symptomatic heart failure. Until recently, the effect of such treatment
in patients with preserved LV function has not been known. The results from the Heart Outcome Prevention Evaluation trial
have indicated that long-term treatment with ramipril leads to a significant reduction in cardiovascular events in patients
with atherosclerotic disease, including those with prior myocardial infarction and preserved LV function. These results suggest
that long-term angiotensin-converting enzyme inhibition should also be considered in post-infarction patients with normal
cardiac function. 相似文献