The 4-dimensional spherical color space in the monkey]

Discrimination of colours by macaque rhesus was studied by the method of elaboration of differentiation inhibition of instrumental conditioned responses to colour stimuli. Matrix of probabilities of instrumental reactions to presentation of colour stimuli, the columns of which corresponded to the colours applied, and the lines--to series of experiments with definite reinforced colour--was processed by the method of factor analysis. Four factors describing the used colours in four-dimensional Euclidean space were singled out. Spatial structure of the seven used colours satisfies the equation of four-dimensional sphere. Two first factors are interpreted as colour-opponent red-green and yellow-blue and the third and fourth ones as achromatic light and dark neuronal channels. Perceptive space of colour stimuli based on the data of instrumental behaviour of the monkey corresponds to analogous results obtained by the method of multidimensional scaling of subjective evaluations of super-threshold colour differences for the man.     

The effect of synthetic proteinase inhibitors of the level of human recombinant proinsulin production, secreted by a genetically engineered strain of Bacillus subtilis

Influence of O,O,-diethyl-1-(N-alpha-hydrohexafluoroisobutyryl)amino-1- methylpropylphosphonate and O,O-diisobutyl-1-[2-(ethoxycarbonyl)aminoperfluoroprop-2-yl] -1- methylpropylphosphonate on the level of production of human proinsulin secreted by a genetically engineered culture Bacillus subtilis AJ 73 (pBINS1.0.) has been studied. The above phosphonates, being non-toxic for microorganisms, reduced degradation of proinsulin by serine proteinases.     

Changes in the levels of paramagnetic centers in the mouse liver and a mathematical model of synchronized auto-oscillations

Investigations of circadian rhythms in paramagnetic particles (free radicals and metal complexes) (PP) concentration variations in tissues are under continuation. A mathematical model advanced considers PP biorhythms as self-induced oscillations subjected to weak synchronization by an external source, by geomagnetic field intensity daily variations for example. By computation parameters of the model were obtained giving good agreement between the theory and experimental data. Due to the mathematical model the amplitude of external synchronizer influence is ten times less than the self-amplitude of PP biorhythm. The experiment was performed on the normal mouse liver. ESR signals g = 1.94, 2.00 and 2.25 were studied.