排序方式: 共有244条查询结果,搜索用时 281 毫秒
241.
Levi G. Cleare Daniel Zamith Heino M. Heyman Sneha P. Couvillion Leonardo Nimrichter Marcio L. Rodrigues Ernesto S. Nakayasu Joshua D. Nosanchuk 《Cellular microbiology》2020,22(9)
Histoplasma capsulatum is a dimorphic fungus that most frequently causes pneumonia, but can also disseminate and proliferate in diverse tissues. Histoplasma capsulatum has a complex secretion system that mediates the release of macromolecule‐degrading enzymes and virulence factors. The formation and release of extracellular vesicles (EVs) are an important mechanism for non‐conventional secretion in both ascomycetes and basidiomycetes. Histoplasma capsulatum EVs contain diverse proteins associated with virulence and are immunologically active. Despite the growing knowledge of EVs from H. capsulatum and other pathogenic fungi, the extent that changes in the environment impact the sorting of organic molecules in EVs has not been investigated. In this study, we cultivated H. capsulatum with distinct culture media to investigate the potential plasticity in EV loading in response to differences in nutrition. Our findings reveal that nutrition plays an important role in EV loading and formation, which may translate into differences in biological activities of these fungi in various fluids and tissues. 相似文献
242.
Varshasnata Mohanty Yashwanth Subbannayya Shankargouda Patil Vinuth N. Puttamallesh Mohd. Altaf Najar Keshava K. Datta Sneha M. Pinto Sameera Begum Neeta Mohanty Samapika Routray Riaz Abdulla Jay Gopal Ray David Sidransky Harsha Gowda T. S. Keshava Prasad Aditi Chatterjee 《Journal of cell communication and signaling》2021,15(3):447
243.
244.