全文获取类型
收费全文 | 257篇 |
免费 | 10篇 |
出版年
2022年 | 1篇 |
2021年 | 4篇 |
2020年 | 3篇 |
2019年 | 4篇 |
2018年 | 2篇 |
2017年 | 4篇 |
2016年 | 4篇 |
2015年 | 13篇 |
2014年 | 14篇 |
2013年 | 17篇 |
2012年 | 25篇 |
2011年 | 24篇 |
2010年 | 9篇 |
2009年 | 9篇 |
2008年 | 14篇 |
2007年 | 9篇 |
2006年 | 9篇 |
2005年 | 10篇 |
2004年 | 12篇 |
2003年 | 7篇 |
2002年 | 11篇 |
2001年 | 9篇 |
2000年 | 6篇 |
1999年 | 5篇 |
1997年 | 3篇 |
1996年 | 2篇 |
1995年 | 2篇 |
1994年 | 3篇 |
1993年 | 1篇 |
1992年 | 4篇 |
1991年 | 1篇 |
1990年 | 1篇 |
1989年 | 2篇 |
1987年 | 6篇 |
1986年 | 4篇 |
1985年 | 1篇 |
1984年 | 3篇 |
1983年 | 1篇 |
1980年 | 1篇 |
1979年 | 1篇 |
1975年 | 1篇 |
1974年 | 2篇 |
1971年 | 1篇 |
1969年 | 1篇 |
1966年 | 1篇 |
排序方式: 共有267条查询结果,搜索用时 546 毫秒
261.
Seven-Year Results of Thinning and Burning Restoration Treatments on Old Ponderosa Pines at the Gus Pearson Natural Area 总被引:1,自引:0,他引:1
Kimberly F. Wallin Thomas E. Kolb Kjerstin R. Skov Michael R. Wagner 《Restoration Ecology》2004,12(2):239-247
Abstract We examined the 7‐year effects of three restoration treatments on leaf physiology and insect‐resistance characteristics of pre‐settlement age ponderosa pines (Pinus ponderosa Dougl. ex Laws.) at the Gus Pearson Natural Area (GPNA) in northern Arizona. Restoration treatments were: (1) thinned in 1993 to approximate pre‐Euro‐American settlement stand structure, (2) thinned plus prescribed burned in 1994 and 1998, and (3) untreated control. Tree physiological and insect‐resistance characteristics were measured in year 2000, 7 years after thinning, using the same procedures as an earlier study performed in 1996. Consistent with the 1996 results, pre‐dawn water potential in 2000 was consistently lower in the control than both thinned treatments. Both thinned treatments continued to have increased foliar nitrogen concentration in leaves 7 years after treatment. However lower leaf nitrogen concentration in the thinned and burned compared with the thinned treatment suggests lower nitrogen availability to trees in repeatedly burned plots. Analysis of leaf gas exchange characteristics and carbon isotope content (δ13C) suggests continued stimulation of photosynthesis by both thinning treatments. Differences among treatments in resin volume, a measure of bark beetle resistance, depended on season of measurement. Trees in both thinning treatments continued to have increased leaf toughness, a measure of resistance to insect folivores. Our results show that many beneficial effects of restoration treatments on carbon, water, and nitrogen relations and insect‐resistance characteristics of pre‐settlement ponderosa pines continue to be expressed 7 years after treatment at the GPNA. 相似文献
262.
Peter Vilhelm Skov Peter G. Bushnell Bjørn Tirsgaard John Fleng Steffensen 《Polar Biology》2009,32(2):215-223
The present work was performed to test the hypothesis that Antarctic teleosts rely mostly on cholinergic inhibition for autonomic
modulation of the heart. The effects of adrenaline on the inotropic properties on paced, isometrically contracting muscle
strips were examined in two distinct Antarctic teleosts, the haemoglobinless icefish Chaenocephalus aceratus and the red-blooded Notothenia coriiceps. All tissues examined revealed a negative force-frequency relationship. Under baseline conditions C. aceratus contracted with a force twice as great as that of N. coriiceps. While the degree to which ventricular tissues responded to adrenaline varied between species, adrenergic stimulation significantly
increases myocyte contraction force in this group of fishes. Contraction and relaxation times were not significantly affected
by adrenaline concentration while absolute rates of contraction were. Adrenergic stimulation does not enable tissues to achieve
higher contraction frequencies, but is shown to be a potent modulator of contraction force. 相似文献
263.
Preben Kirkegaard Peter Skov Olsen Steen Seier Poulsen Ebba Nexø 《Regulatory peptides》1983,7(4):367-372
Brunner's glands of the duodenum are innervated by cholinergic and VIP-ergic nerves, and the glands have been shown to contain epidermal growth factor (EGF). In this study the effect of VIP and acetylcholine (Ach) on secretion of EGF from Brunner's glands was investigated in the rat. Intravenous infusion of VIP stimulated the flow rate of duodenal secretion, an effect which was inhibited by atropine. Ach alone did not significantly increase flow rate, and combined infusion of VIP and Ach induced the same flow as VIP alone. Concentration of EGF in duodenal secretion was increased by infusion of Ach, and this effect was potentiated by VIP. Infusion of VIP alone did not influence EGF concentration. EGF output from Brunner's glands was significantly stimulated by i.v. infusion of VIP and of Ach and combined infusion further increased EGF output. The study has demonstrated exocrine secretion of EGF from Brunner's glands, and it is suggested that stimulation is mediated by interaction of neuronal VIP and Ach. 相似文献
264.
Nancy G. Wehner Michael Skov George Shopp Meredith S. Rocca Janet Clarke 《Birth defects research. Part B, Developmental and reproductive toxicology》2009,86(2):108-116
BACKGROUND : Natalizumab is a humanized monoclonal immunoglobulin G4 antibody directed against the human α4 integrin subunit disrupting interaction with its ligands. As α4 integrins and/or their ligands appear to be involved in reproductive function, the effects of natalizumab on fertility in male and female guinea pigs were investigated. METHODS : Natalizumab was administered by bolus intravenous injection every other day at doses of 0, 3, 10, and 30 mg/kg. Males began treatment at least 28 days prior to mating until necropsy (approximately 3 to 5 days after mating). Dosing in females was done from gestational day (GD) of an existing pregnancy to GD 30 of a second pregnancy. RESULTS : In male guinea pigs, natalizumab treatment had no effect on sperm parameters, reproductive organ weights, organ-weight ratios, or histology of the testis or epididymis. Natalizumab did not affect the ability of treated males to produce pregnancies in untreated females. In female guinea pigs, no treatment-related changes were seen in uterine weights or ovary weights. Pregnancy rates were reduced in females treated with 30 mg/kg natalizumab, but not those treated with 3 or 10 mg/kg. Pregnancy rates were 63.3, 66.7, 66.7, and 29.6% for groups treated with 0, 3, 10, and 30 mg/kg, respectively. Effects observed at 30 mg/kg were at exposures 36-fold those observed in humans. CONCLUSIONS : Natalizumab had no effects on male fertility, but did result in a reduction in pregnancy rates in females treated with the high dose of 30 mg/kg. Birth Defects Res (Part B)86: 108-116, 2009. © 2009 Wiley-Liss, Inc. 相似文献
265.
266.
Vascular casts of 3 species of Chondrichthyes, 1 of Dipnoi, 1 of Chondrostei and 14 species of the Teleostei were examined by light and scanning electron microscopy in order to give a qualitative and quantitative analysis of interarterial anastomoses (iaas) that indicate the presence (or absence) of a secondary vascular system (SVS). Anastomoses were found to originate from a variety of different primary blood vessels, many of which have not been previously identified as giving rise to secondary vessels. Segmental arteries derived from the dorsal aorta and supplying body musculature were major sites of origin of the SVS, although there was considerable variation in where, in the hierarchy of arterial branching, the anastomoses occurred. The degree of investment in a SVS was species specific, with more active species having a higher degree of secondary vascularisation. This difference was quantified using an absolute count of iaas between Anguilla reinhardtii and Trachinotus baillonii. A range of general features of the SVS is also described. No evidence of iaas was found on the coeliac, mesenteric or renal circulation in any species. Evidence of iaas was lacking in the dipnoan and chondrichthyan species examined, suggesting that a SVS is restricted to Actinopterygii. The presence and distribution of a SVS does not appear to be exclusively linked to phylogenetic position, but rather to the physiological adaptation of the species.The online version of the original article can be found at 相似文献
267.
Ricardo F. Caroço Marta Bevilacqua Ibrahim Armagan Paloma A. Santacoloma Jens Abildskov Thomas Skov Jakob K. Huusom 《Biotechnology progress》2019,35(2):e2762
Different opportunities are explored to evaluate quality variation in raw materials from biological origin. Assessment of raw materials attributes is an important step in a bio-based production as fluctuations in quality are a major source of process disturbance. This can be due to a variety of biological, seasonal, and supply scarcity reasons. The final properties of a product are invariably linked with the initial properties of the raw material. Thus, the operational conditions of a process can be tuned to drive the product to the required specification based on the quality assessment of the raw material being processed. Process analytical technology tools which enable this assessment in a far more informative and rapid manner than current industrial practices that rely on rule-of-thumb decisions are assessed. An example with citrus peels is used to demonstrate the conceptual and performance differences of distinct quality assessment approaches. The analysis demonstrates the advantage of characterization through multivariate data analysis coupled with a complementary spectroscopic technique, near-infrared spectroscopy. The quantitative comparative analysis of three different approaches, discriminant classification based on expert-knowledge, unsupervised classification, and spectroscopic correlation with reference physicochemical variables, is performed in the same dataset context. © 2018 Her Majesty the Queen in Right of Canada © 2018 American Institute of Chemical Engineers Biotechnol. Prog., 35: e2762, 2019. 相似文献