排序方式: 共有98条查询结果,搜索用时 15 毫秒
91.
Small cell lung cancer presenting as acute leukaemia 总被引:1,自引:0,他引:1
R. Ali F. Ozkalemkas T. Ozcelik U. Ozan V. Ozkocaman A. Tunali S. Balaban-Adim 《Cytopathology》2005,16(5):262-263
92.
İmge Kunter Nazife Hürer Hayrettin Ozan Gülcan Barış Öztürk İrfan Doğan Gönül Şahin 《Biological trace element research》2017,175(1):42-49
Breast milk contributes towards optimal nutrition for infants. However, studies showed that it can also contain different toxins and heavy metals, which reduce its health benefits. The aim of this study is to determine the level of contaminants such as aflatoxin M1 (AFM1), Pb, Cd, As, and Hg in breast milk samples from Famagusta, Cyprus. Correlations between moldy food consumption, smoking habits of the mothers, and contaminant levels in breast milk were also investigated. Breast milk samples from 50 lactating mothers in rural and urban areas of Famagusta District were analyzed for AFM1 by ELISA. Eighty percent of them were found to be contaminated with AFM1 with the mean measurement of 7.84?±?1.72 ng/l. Socio-demographic status, moldy food consumption habits, and smoking status do not have any effect on the AFM1 levels observed in breast milk. Heavy metal levels in breast milk were examined by inductively coupled plasma mass spectrometry, and the mean measurements were1.19?±?1.53 ppm for Pb, 0.73?±?0.58 ppm for As, 0?±?0.20 ppm for Hg, and 0.45?±?0.23 ppm for Cd. This study indicates that the levels of these contaminants in breast milk samples obtained in Famagusta District are well within the acceptable levels. However, the presence of AFM1 and heavy metals still may pose risks for infant health. 相似文献
93.
Mustafa Unal Robert L. Wilson Corey P. Neu Ozan Akkus 《Journal of biophotonics》2022,15(1):e202100212
We investigated for the first time zonal-dependent water distribution in articular cartilage by Raman spectroscopy (RS). We further investigated the association of histopathologic score with RS- and magnetic resonance imaging (MRI)-based water measurements. Cadaveric human cartilage plugs (N = 16) with different osteoarthritis (OA) severity were used. Water content distribution in cartilage zones was probed using RS- and MRI-based techniques. Histopathologic scoring was performed by two independent observers blindly. Moderate associations existed between RS- and MRI-based water measurements across all cartilage zones. RS-based analysis of different water compartments helped assign the origin of the T2 signal collected from the various cartilage zones. RS-based water parameters significantly correlated with OA-severity score, whereas MRI-based water measurements did not. RS can probe different water compartments in cartilage zones and predict up to 66% of the variation observed in the histopathologic score. RS-based water measurement could be developed further to assess cartilage quality in the clinic. 相似文献
94.
Kotan Zeynep Bican Aylin Kotan Vahap Ozan Bora Ibrahim Yalvac Hayriye Dilek Ozkaya Güven Akkaya Cengiz 《Sleep and biological rhythms》2015,13(1):99-105
Sleep and Biological Rhythms - To determine the effects of trazodone, mirtazapine and hydroxyzine on sleep profiles of dysthymic disorder (DD) women with selective serotonin reuptake inhibitor... 相似文献
95.
Hierarchical relationship between bone traits and mechanical properties in inbred mice 总被引:2,自引:2,他引:0
Abstract
Osteoporotic fracture incidence and underlying risk factors like low peak bone mass are heritable, but the genetic basis of
osteoporosis remains poorly understood. Based on beam theory, stating that mechanical properties of a structure depend on
both the amount and quality of the constituent materials, we investigated the relationship between whole bone mechanical properties
and a set of morphological and compositional traits in femurs of eight inbred mouse strains. K-means cluster analysis revealed
that individual femora could be classified reliably according to genotype based on the combination of bone area (tissue amount),
moment of inertia (tissue distribution), and ash content (tissue quality). This trait combination explained 66–88% of the
inter-strain variability in four whole-bone mechanical properties that describe all aspects of the failure process, including
measures of brittleness. Stiffness and maximum load were functionally associated with cortical area, while measures of brittleness
were associated with ash content. In contrast, work-to-failure was not directly related to a single trait but depended on
a combination of trait magnitudes. From these findings, which were entirely consistent with established mechanical theory,
we developed a hierarchical paradigm relating the mechanical properties that define bone fragility with readily measurable
phenotypic traits that exhibit strong heritability. This paradigm will help guide the search for genes that underlie fracture
susceptibility and osteoporosis. Moreover, because the traits we examined are measurable with non-invasive means, this approach
may also prove directly applicable to osteoporosis risk assessment. 相似文献
96.
97.
Huseyin Ozan Tekin Mesut Karahan Turker Tekin Erguzel Tugba Manici Muhsin Konuk 《Journal of biological physics》2018,44(4):579-590
In this paper, radiation shielding parameters such as mass attenuation coefficients and half value layer (HVL) of some antioxidants are investigated using MCNPX (version 2.4.0). The validation of the generated MCNPX simulation geometry for antioxidant structures is provided by comparing the results with standard WinXcom data for radiation mass attenuation coefficients of antioxidants. Very good agreement between W?NXCOM and MCNPX was obtained. The results from the validated geometry were used to calculate the shielding parameters of different antioxidants. The radiation attenuation properties of each antioxidant were compared with each other. The results showed that, on average, the highest and the lowest radiation mass attenuation coefficients were observed on hesperidin and delphinidin chloride, respectively. It can be concluded that Monte Carlo simulation is a strong tool and an alternate method where experimental investigations are not possible and a standard simulation setup can be used in further studies for different biological structures. It can also be concluded that the obtained results from this study are very useful for radiology and radiotherapy applications where antioxidants are frequently used. 相似文献
98.
Ozan Yetis Ozge Guner Ibrahim Akkaya Ensari Guneli Alper Bagriyanik Serhat Tozburun 《Journal of biophotonics》2022,15(1):e202100197
Laser nerve stimulation using near-infrared laser irradiation has recently been studied in the peripheral nervous system as an alternative method to conventional electrical nerve stimulation. Bringing this method to the vagus nerve model could leverage this emerging stimulation approach to be tested in broader preclinical applications. Here, we report the capability of the laser nerve stimulation method on the rat vagus nerve bundle with a 1505-nm diode laser operated in continuous-wave mode. Studies of the stimulation threshold and laser-induced acute thermal injury to the nerve bundle were also performed to determine a temperature window for safe, reliable and reproducible laser stimulation of the rat vagus nerve bundle. The results show that laser stimulation of the vagus nerve bundle provides reliable and reproducible nerve stimulation in a rat model. These results also confirm a threshold temperature of >42°C with acute nerve damage observed above 46°C. A strong correlation was obtained between the laser time required to raise the nerve temperature above the stimulation threshold and the mean arterial pressure response. Advantages of the method such as non-contact delivery of external stimulus signals at mm scaled distance in air, enhanced spatial selectivity and electrical artefact-free measurements may indicate its potential to counteract the side effects of conventional electrical vagus nerve stimulation. 相似文献