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Gabriella Gruden Patrizia Carucci Federica Barutta Davina Burt Arianna Ferro Emanuela Rolle Silvia Pinach Maria Lorena Abate Donata Campra Marilena Durazzo 《Cell stress & chaperones》2021,26(1):151
Heat shock protein 27 (HSP27), an intracellular molecular chaperone, is involved in the pathogenesis of cancer by promoting both tumor cell proliferation and resistance to therapy. HSP27 is also present in the circulation and circulating HSP27 (sHSP27) can elicit an autoimmune response with production of antibodies. Levels of sHSP27 are enhanced in patients with hepatocellular carcinoma (HCC); it is, however, unknown whether changes in HSP27 antibody levels occur in patients with HCC and can be exploited as a circulating biomarker of HCC. Our aim was to assess the potential association between newly diagnosed HCC and serum anti-HSP27 antibody levels. In this cross-sectional study, anti-HSP27 antibody levels were measured in serum samples from 71 HCC patients, 80 subjects with chronic liver disease, and 38 control subjects by immunoenzymatic assay. Anti-HSP27 antibody levels did not differ significantly among groups. However, in patients with chronic active hepatitis/cirrhosis, anti-HSP27 levels were significantly higher in subjects with a positive history of alcoholism (p = 0.03). Our data do not support the hypothesis that anti-HSP27 antibody levels may help identify patients with HCC among subjects with chronic liver disease. However, our finding that alcohol-related liver disease is associated with higher anti-HSP27 levels is novel and deserves further investigations. 相似文献
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Alonso Alberto Pérez Javier Monroy Silvia López-Rojo Naiara Basaguren Ana Bosch Jaime Boyero Luz 《Ecosystems》2021,24(6):1436-1449
Ecosystems - Leaf litter of alder (Alnus glutinosa) is a key resource to detrital stream food webs. Due to its high quality and palatability, it is readily colonised by microorganisms and consumed... 相似文献
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Jaime A. Teixeira da Silva Judit Dobránszki Silvia Ross 《In vitro cellular & developmental biology. Plant》2013,49(1):1-16
In plant tissue culture research, there is a constant need to search for novel substances that could result in better or more efficient growth in vitro. A relatively unknown compound, phloroglucinol (1,3,5-trihydroxybenzene), which is a degradation product of phloridzin, has growth-promoting properties. Phloroglucinol increases shoot formation and somatic embryogenesis in several horticultural and grain crops. When added to rooting media together with auxin, phloroglucinol further stimulates rooting, most likely because phloroglucinol and its homologues act as auxin synergists or auxin protectors. Of particular interest is the ability of phloroglucinol—a precursor in the lignin biosynthesis pathway—to effectively control hyperhydricity through the process of lignification, thus maximizing the multiplication rate of woody species and other species that are difficult to propagate. Phloroglucinol has also been used to improve the recovery of cryopreserved Dendrobium protocorms, increasing the potential of cryopreservation for application in ornamental biotechnology. Phloroglucinol demonstrates both cytokinin-like and auxin-like activity, much like thidiazuron, and thus has considerable potential for application in a wide range of plant tissue culture studies. 相似文献
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Eleonora Paparelli Sandro Parlanti Silvia Gonzali Giacomo Novi Lorenzo Mariotti Nello Ceccarelli Joost T. van Dongen Katharina K?lling Samuel C. Zeeman Pierdomenico Perata 《The Plant cell》2013,25(10):3760-3769
A plant’s eventual size depends on the integration of its genetic program with environmental cues, which vary on a daily basis. Both efficient carbon metabolism and the plant hormone gibberellin are required to guarantee optimal plant growth. Yet, little is known about the interplay between carbon metabolism and gibberellins that modulates plant growth. Here, we show that sugar starvation in Arabidopsis thaliana arising from inefficient starch metabolism at night strongly reduces the expression of ent-kaurene synthase, a key regulatory enzyme for gibberellin synthesis, the following day. Our results demonstrate that plants integrate the efficiency of photosynthesis over a period of days, which is transduced into a daily rate of gibberellin biosynthesis. This enables a plant to grow to a size that is compatible with its environment. 相似文献
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Abstract Morphological and ecological observations on four fleshy crustose algae collected in the eulittoral and upper sublittoral zone of the Island of Gorgona: Myrionema liechtenstenii Hauck, Hildenbrandia canariensis B?rgesen, Peyssonnelia armorica (P. et H. Crouan) Weber-van Bosse in B?rgesen and Cruoria cruoriaeformis (P. et H. Crouan) Denizot are reported. For each species, information on some aspects of their ecology, geographical distribution and notes on their vegetative and reproductive morphology are given. 相似文献
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Ilaria Papi Giuseppina Pardi Silvia Lenzini Lisandro Benedetti Cecchi Francesco Cinelli 《Plant biosystems》2013,147(3-4):549-593
Abstract Benthic marine flora of Tuscan Archipelago has been studied. Several samples were collected along five islands and some rocks. This paper is a compendium of new and already published data, in which 267 species, varieties, forms and stadia of algae and seagrasses are listed: 5 Bangiophyceae, 182 Florideophyceae, 45 Phaeophyceae, 6 Chlorophyceae, 28 Bryopsidophyceae, 1 Angiospermae. 相似文献