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Signe Damm Frances Lordan Antony Murphy Mark McMillen Robert Pollard James H. Rice 《Plasmonics (Norwell, Mass.)》2014,9(6):1371-1376
In this paper, we probed surface-enhanced Raman scattering (SERS) and surface-enhanced fluorescence (SEF) from probe molecule Rhodamine 6G (R6G) on self-standing Au nanorod array substrates made using a combination of anodization and potentiostatic electrodeposition. The initial substrates were embedded within a porous alumina template (AAO). By controlling the thickness of the AAO matrix, SEF and SERS were observed exhibiting an inverse relationship. SERS and SEF showed a non-linear response to the removal of AAO matrix due to an inhomogeneous plasmon activity across the nanorod which was supported by FDTD calculations. We showed that by optimizing the level of AAO thickness, we could obtain either maximized SERS, SEF or simultaneously observe both SERS and SEF together. 相似文献
223.
Preuschoft Signe Wang Xin Aureli Filippo de Waal Frans B. M. 《International journal of primatology》2002,23(1):29-50
Affiliative postconflict reunions—reconciliations—of former opponents were first demonstrated in the chimpanzees at the Arnhem Zoo. Since then methods have been considerably refined, and reconciliation has been demonstrated in a large number of primates and also some gregarious nonprimates. This study, conducted with a different captive group, is the first to use the revised methodology with chimpanzees. We analyzed a total of 297 agonistic conflicts with the PC–MC method: we observed focal individuals for 15 min after a conflict and during matched control observations the next day. The mean conciliatory tendency of the 16 chimpanzees was 41%, with a range in different age-sex classes of 58% (among adult females) to 19% (among adult vs. immature males). After conflicts, former opponents were selectively attracted to one another. Preferential contact with previous opponents persisted when activity level during matched controls was controlled for statistically. Opponents that were frequent grooming partners reconciled more frequently, but the frequency of agonistic support had no such effect. Our findings thus confirm the existence of reconciliation in chimpanzees, which show one of the highest conciliatory tendencies among primate species. 相似文献
224.
HAI‐2 stabilizes,inhibits and regulates SEA‐cleavage‐dependent secretory transport of matriptase
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Christoffer Soendergaard Signe Skovbjerg Stine Friis Martin N. Andersen Vincent Ellis Makiko Kawaguchi Hiroaki Kataoka Thomas H. Bugge Lotte K. Vogel 《Traffic (Copenhagen, Denmark)》2017,18(6):378-391
It has recently been shown that hepatocyte growth factor activator inhibitor‐2 (HAI‐2) is able to suppress carcinogenesis induced by overexpression of matriptase, as well as cause regression of individual established tumors in a mouse model system. However, the role of HAI‐2 is poorly understood. In this study, we describe 3 mutations in the binding loop of the HAI‐2 Kunitz domain 1 (K42N, C47F and R48L) that cause a delay in the SEA domain cleavage of matriptase, leading to accumulation of non‐SEA domain cleaved matriptase in the endoplasmic reticulum (ER). We suggest that, like other known SEA domains, the matriptase SEA domain auto‐cleaves and reflects that correct oligomerization, maturation, and/or folding has been obtained. Our results suggest that the HAI‐2 Kunitz domain 1 mutants influence the flux of matriptase to the plasma membrane by affecting the oligomerization, maturation and/or folding of matriptase, and as a result the SEA domain cleavage of matriptase. Two of the HAI‐2 Kunitz domain 1 mutants investigated (C47F, R48L and C47F/R48L) also displayed a reduced ability to proteolytically silence matriptase. Hence, HAI‐2 separately stabilizes matriptase, regulates the secretory transport, possibly via maturation/oligomerization and inhibits the proteolytic activity of matriptase in the ER, and possible throughout the secretory pathway. 相似文献
225.
Vardha Ismail Linda G. Zachariassen Annie Godwin Mane Sahakian Sian Ellard Karen L. Stals Emma Baple Kate Tatton Brown Nicola Foulds Gabrielle Wheway Matthew O. Parker Signe M. Lyngby Miriam G. Pedersen Julie Desir Allan Bayat Maria Musgaard Matthew Guille Anders S. Kristensen Diana Baralle 《American journal of human genetics》2022,109(7):1217-1241
226.
Sbastien Descamps Francisco Ramírez Sigurd Benjaminsen Tycho Anker‐Nilssen Robert T. Barrett Zofia Burr Signe Christensen‐Dalsgaard Kjell‐Einar Erikstad David B. Irons Svein‐Hkon Lorentsen Mark L. Mallory Gregory J. Robertson Tone Kirstin Reiertsen Hallvard Strm
ystein Varpe Sbastien Lavergne 《Global Change Biology》2019,25(12):4081-4091
The timing of annual events such as reproduction is a critical component of how free‐living organisms respond to ongoing climate change. This may be especially true in the Arctic, which is disproportionally impacted by climate warming. Here, we show that Arctic seabirds responded to climate change by moving the start of their reproduction earlier, coincident with an advancing onset of spring and that their response is phylogenetically and spatially structured. The phylogenetic signal is likely driven by seabird foraging behavior. Surface‐feeding species advanced their reproduction in the last 35 years while diving species showed remarkably stable breeding timing. The earlier reproduction for Arctic surface‐feeding birds was significant in the Pacific only, where spring advancement was most pronounced. In both the Atlantic and Pacific, seabirds with a long breeding season showed a greater response to the advancement of spring than seabirds with a short breeding season. Our results emphasize that spatial variation, phylogeny, and life history are important considerations in seabird phenological response to climate change and highlight the key role played by the species’ foraging behavior. 相似文献
227.
KISSMig – a simple model for R to account for limited migration in analyses of species distributions
Detecting the legacy of time‐lagged migration in species ranges is an urgent matter for understanding range dynamics. KISSMig is a simple migration model which generates maps of accessibility from areas of origin and allows the generation and testing of hypotheses about the influence of specific spread patterns on species distributions. KISSMig has important applications: 1) uncovering the influence of limited migration relative to other drivers, 2) detecting areas of origin and their importance as sources of migration, and 3) accounting for limited migration in modeling species distributions. Here we introduce KISSMig and use the oak species Quercus cerris to illustrate these applications. 相似文献
228.
In order to understand the effect of a nitrogen gradient on the intraspecific and interspecific competition between plants, the two species Erodium cicutarium and Geranium pusillum were grown in a response-surface competion experiment at three different densities along a nitrogen gradient consisting of four different nitrogen levels. Seed set data were estimated from biomass measurements and fitted to a generalized hyperbolic competition model, and the probabilities of different ecological scenarios were calculated. The model predicted that E. cicutarium is competitively superior along most of the nitrogen gradient. This prediction was contrary to our prior expectations which were based on the occurance of the two species in natural habitats. 相似文献
229.
Coefficients for active transport of ions and heat in vesicles with Ca2+-ATPase from sarcoplasmic reticulum are defined in terms of a newly proposed thermodynamic theory and calculated using experiments reported in the literature. The coefficients characterize in a quantitative manner different performances of the enzyme isoforms. Four enzyme isoforms are examined, namely from white and red muscle tissue, from blood platelets, and from brown adipose mitochondria. The results indicate that the isoforms have a somewhat specialized function. White muscle tissue and brown adipose tissue have the same active transport coefficient ratio, but the activity level of the enzyme in white muscle is higher than in brown adipose tissue. The thermogenesis ratio is high in both white muscle and brown adipose tissue, in agreement with a specific role in nonshivering thermogenesis. Other isoforms do not have this ability to generate heat. A calcium-dependence of the coefficients is found, which can be understood as being in accordance with the role of this ion as a messenger in muscle contraction as well as in thermogenesis. The investigation points to new experiments related to structure as well as to function of the isoforms. 相似文献
230.