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排序方式: 共有312条查询结果,搜索用时 15 毫秒
1.
T I Titova T N Sidorova S A Radkevich N G Antsiferova A F Moroz 《Zhurnal mikrobiologii, epidemiologii, i immunobiologii》1985,(8):80-84
The influence of immunization with P. aeruginosa vaccine on the immune status of volunteer donors has been studied. Immunization with P. aeruginosa vaccine in doses of 0.5-0.5-1.0 ml at intervals of 7 days has been found to lead to the 13-fold increase of the titer of specific antibodies, lasting for 3-4 months, which ensures the possibility of obtaining anti-P. aeruginosa hyperimmune plasma with standard titers. The injection of P. aeruginosa vaccine to donors leads to the activation of humoral immunity simultaneously with the increase of the absolute and relative number of rosette-forming B-lymphocytes without essential changes in the amount of rosette-forming T-lymphocytes. 相似文献
2.
High level of divergence of male-reproductive-tract proteins, between Drosophila melanogaster and its sibling species, D. simulans 总被引:1,自引:0,他引:1
We compared male-reproductive-tract polypeptides of Drosophila melanogaster
and D. simulans by using two-dimensional gel electrophoresis. Approximately
64% of male-reproductive-tract polypeptides were identical between two
randomly chosen isofemale lines from these two species, compared with 83%
identity for third-instar imaginal wing-disc polypeptides. Qualitatively
similar differences were found between reproductive tracts and imaginal
discs when D. sechellia was compared with D. melanogaster and with D.
simulans. When genic polymorphism was taken into account, approximately 10%
of male- reproductive-tract polypeptides were apparently fixed for
different alleles between D. melanogaster and D. simulans; this proportion
is the same as that found for soluble enzymes by one-dimensional gel
electrophoresis. Strikingly, approximately 20% of male-reproductive- tract
polypeptides of either D. melanogaster or D. simulans had no detectable
homologue in the other species. We propose that proteins of the Drosophila
male reproductive tract may have diverged more extensively between species
than have other types of proteins and that much of this divergence may
involve large changes in levels of polypeptide expression.
相似文献
3.
N Iu Sidorova V A Nikolaev A N Surovaia A L Zhuze G V Gurski? 《Molekuliarnaia biologiia》1991,25(3):706-717
Cystine peptide dimer (Lys-Gly-Val-Cys-Val-N2H2Dns)2 with S-S bridge was synthesized and its interactions with DNA and synthetic polynucleotides have been studied by optical spectroscopy methods. By recording fluorescent titration curves we have shown that the affinity of the peptide to different synthetic polynucleotides decreases in the order: poly(dG).poly(dC) greater than poly(dA).poly(dT) greater than poly(dGC).poly(dGC). The stability of complexes to increasing concentrations of NaCl diminishes in the same order. The association constant is about 20-fold greater for peptide binding to poly(dG).poly(dC) than to poly(dA).poly(dT). By using circular dichroism and fluorescence measurements we have shown that the peptide competes for the binding sites on DNA with two minor-groove binding antibiotics--distamycin A and sybiromycin. These results have suggested that the peptide also binds in the DNA minor groove. Investigation of the interactions between such peptides and DNA may be useful for constructing ligands with combined specificity to DNA. 相似文献
4.
The electroencephalographic and autonomic correlates of the mental reproduction of emotional states]
O A Sidorova M B Kostiunina M A Kulikov 《Zhurnal vysshe? nervno? deiatelnosti imeni I P Pavlova》1991,41(5):891-898
The present study is devoted to the analysis of changes of bioelectrical and vegetative indices at mental reproduction of emotional states by man. Analysis is conducted of the data of mapping of intracortical interactions depending on the dynamics of R-R interval changes. Two stages of mental reproduction of emotions are revealed which are characterized by the presence of different centers of integration--in the frontal and temporal parts of the brain cortex. It is shown that at maximum emotional stress the integration center shifts from the frontal regions to the temporal region of the left hemisphere. 相似文献
5.
The frequency of skin-galvanic (SGR) and motor reactions was analyzed at recognition of human emotional state by mimics. 31 healthy persons and 54 patients with lesions of temporal and frontoparietal areas of both cerebral hemispheres were examined. It has been established that the process of recognition takes place by stages: at first - at intuitive level accompanied by SGR, and then at the level of making decision completed by a motor or verbal reaction. Efficiency of recognition at the first stage does not so much depend on lesion localization as at the second stage. Pathology of the left hemisphere affects mainly the stage of making decision, and of the right one - the process of recognition as a whole. 相似文献
6.
A I Brusilovski? G N Krivosheina V A Golubev T P Sidorova 《T?Sitologii?a i genetika》1983,17(4):49-54
The content of X-sex chromatin was studied in the buccal epithelial cells of pregnant women with Rh-negative blood. It was found that in women with a titer of Rh antibodies the amount of cells with X-sex chromatin decreases. A clinical-cytological correlation in the mother-placenta-fetus system was traced in pregnant women with a Rh antibody titer. 相似文献
7.
The influence of medium acidity on the intensity of light-dependent antibacterial activity of chlorophyllides isolated from biomass of microscopic green alga Westella botryoides has been studied. This light-dependent antibacterial activity has been shown to be maximum at low pH values. The ability to suppress the bacterial growth under the action of light decreases in neutral and alkaline media. It has been concluded that the reason of increase of light-dependent antibacterial activity of chlorophyllides at low pH values is formation of pheophorbides out of them 相似文献
8.
9.
M. E. Palkeeva M. V. Sidorova A. S. Molokoedov A. A. Az’muko Zh. D. Bespalova T. V. Sharf E. N. Mamochkina E. E. Efremov M. M. Rogova N. A. Mironova K. A. Zykov S. P. Golitsyn 《Russian Journal of Bioorganic Chemistry》2013,39(3):252-258
Fragments corresponding to the 83–98 sequence of the first extracellular loop and to the 168–192 and 171–182 sequences of the second extracellular loop of the M2-muscarinic receptor (antibodies to this receptor could be markers of early symptoms of heart disorders) were synthesized by solid phase method using the Fmoc-SPPS strategy. A new conformational antigen with the natural location of the disulfide bridge was prepared by selective formation of disulfide bond between the corresponding cysteine residues in the synthe-sized peptides and characterized. The comparative analysis of reactivity of the synthesized peptides towards sera from patients which had no organic heart disease was performed. A new conformational antigen was effectively bound to the sera from patients with idiopathic arrhythmias, but without symptoms of organic heart disease. 相似文献
10.
Sidorova M. V. Palkeeva M. E. Avdeev D. V. Molokoedov A. S. Ovchinnikov M. V. Azmuko A. A. Serebryakova L. I. Veselova O. M. Studneva I. M. Pisarenko O. I. 《Russian Journal of Bioorganic Chemistry》2020,46(1):32-42
Russian Journal of Bioorganic Chemistry - The full-length rat galanin (GWTLNSAGYLLGPHAIDNHRSFSDKHGLT-NH2, G29) was prepared by the solid phase peptide synthesis using the Fmoc-strategy. The peptide... 相似文献