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51.
The pelagic larval stage of a pleuronectiform samarid, Plagiopsetta glossa, is described and illustrated, for the first time, from a 8.4-mm BL postflexion specimen collected off Tosa Bay, southern Japan. The larva is distinctive in having broad, semitransparent pterygiophore zones on the dorsal and anal fins, a trailing gut, flexible S-shaped pelvic bone, and a skin fold under the throat. These characteristics are shared with poecilopsettid larvae, suggesting a close relationship between the two families. 相似文献
52.
Larvae of two paralichthyids, Pseudorhombus oculocirris and P. arsius, are described and illustrated from specimens collected off Tosa Bay, southern Japan. Peudorhombus oculocirris larvae (5 specimens, 4.5–7.8 mm BL) are characteristic in having 6 or 7 elongated anterior dorsal fin rays and poorly developed
head spines and melanophores on the tail. Pseudorhombus arsius larvae (3 specimens, 5.3–8.4 mm BL) are distinctive in having 11 or 12 elongated anterior dorsal fin rays and well-developed
head spines, including a row of spines on the sphenotic.
Received: June 28, 2001 / Revised: November 2, 2001 / Accepted: November 22, 2001 相似文献
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Nanako Takeda-Hirokawa Lian-pin Neoh Hiroaki Akimoto Hiroshi Kaneko Takashi Hishikawa Iwao Sekigawa Hiroshi Hashimoto Shun-ichi Hirose Tsutomu Murakami Naoki Yamamoto Tohru Mimura Yutaro Kaneko 《Microbiology and immunology》1997,41(9):741-745
To clarify the mechanism by which curdlan sulfate (CRDS) inhibits human immunodeficiency virus (HIV)-1 infection, we examined its influence on the binding of gp120 to CD4 molecules on T cells and macrophages, as well as on the production of TNF-α by gp120-stimulated macrophages (which promotes HIV-1 replication). CRDS treatment of cells not only inhibited the binding of HIV-1 gp120 to CD4+ cells, but also inhibited TNF-α production induced by gp120. Inhibition of HIV-1 infection by CRDS may be related to these two actions. 相似文献
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A new species ofTalaromyces, characterized by development of unusual deep green ascomata on common media, is described and given the nameTalaromyces euchlorocarpius. This species, isolated from soil, also produces ellipsoidal, spinose ascospores, typically biverticillate penicilli, large
ellipsoidal, smooth-walled conidia, and is assigned to the seriesLutei of the sectionTalaromyces. 相似文献
58.
Osteoclast differentiation factor acts as a multifunctional regulator in murine osteoclast differentiation and function. 总被引:24,自引:0,他引:24
E Jimi S Akiyama T Tsurukai N Okahashi K Kobayashi N Udagawa T Nishihara N Takahashi T Suda 《Journal of immunology (Baltimore, Md. : 1950)》1999,163(1):434-442
Osteoclast differentiation factor (ODF), a novel member of the TNF ligand family, is expressed as a membrane-associated protein by osteoblasts/stromal cells. The soluble form of ODF (sODF) induces the differentiation of osteoclast precursors into osteoclasts in the presence of M-CSF. Here, the effects of sODF on the survival, multinucleation, and pit-forming activity of murine osteoclasts were examined in comparison with those of M-CSF and IL-1. Osteoclast-like cells (OCLs) formed in cocultures of murine osteoblasts and bone marrow cells expressed mRNA of RANK (receptor activator of NF-kappaB), a receptor of ODF. The survival of OCLs was enhanced by the addition of each of sODF, M-CSF, and IL-1. sODF, as well as IL-1, activated NF-kappaB and c-Jun N-terminal protein kinase (JNK) in OCLs. Like M-CSF and IL-1, sODF stimulated the survival and multinucleation of prefusion osteoclasts (pOCs) isolated from the coculture. When pOCs were cultured on dentine slices, resorption pits were formed on the slices in the presence of either sODF or IL-1 but not in that of M-CSF. A soluble form of RANK as well as osteoprotegerin/osteoclastogenesis inhibitory factor, a decoy receptor of ODF, blocked OCL formation and prevented the survival, multinucleation, and pit-forming activity of pOCs induced by sODF. These results suggest that ODF regulates not only osteoclast differentiation but also osteoclast function in mice through the receptor RANK. 相似文献
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Hasegawa M Kinoshita K Nishimura C Matsumura U Shionyu M Shionyu M Ikeda S Mizukami T 《Bioorganic & medicinal chemistry letters》2008,18(20):5668-5671
Belactosin A is a potent proteasome inhibitor isolated from Streptomyces metabolites. Here we show that a hydrophobic belactosin A derivative, dansyl-KF33955, can covalently, and specifically, affinity label the catalytic subunits of the 26S proteasome, which consists of the 20S protein degrading core particle and the 19S regulatory particles. The labeling of catalytic subunits proceeds faster in intact proteasomes in vivo than in isolated 20S core particles. These data suggest that the 19S regulatory particle may facilitate entry of the inhibitor into the 20S core particle. This cell-permeable chemical probe is an excellent tool with which to study the interactions of this proteasome inhibitor with proteasomes in intact cells. 相似文献