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Agafonova OV Borovskiĭ IV Demchenko VV Pavlova AM Filatova IM 《Zhurnal mikrobiologii, epidemiologii, i immunobiologii》1999,(1):119-120
During the recent 10 years, 1987-1997, syphilis morbidity was found to increase 60-fold in Omsk Province. In 1997 adolescents constituted 6.0% in the structure of persons who contacted the disease. In this year more than 500 adolescent using drugs were registered in the region. The introduction of drugs by injection was practiced by 9.6% of the adolescents. The program aimed mainly at changing the behavior of young people with orientation on the choice of a healthy mode of life and theirs information about risk factors associated with sex transmitted diseases particularly HIV infection is discussed. 相似文献
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Smol'skaia TT Sizova NV Korovina GI Maslov VP Kevlova NA Novikova VA Bogoiavlenskiĭ GV 《Zhurnal mikrobiologii, epidemiologii, i immunobiologii》1999,(1):57-59
The informatory role of a new marker of HIV infection, characterizing the content of HIV-1 RNA in the biological fluids of the patient's body, is evaluated. The quantitative determination of HIV-1 RNA, carried out in a single assay, was made in the blood of 25 HIV-infected patients. These studies confirmed that the determination of the level of RNA in the plasma (viral load) was a reliable criterion indicating the severity and progress of the disease. The viral load of more than 100,000 copies/ml was a sign prognosticating the future pronounced progress of the disease in spite of moderate clinical manifestations and relatively high values of CD4 cells in the patient's blood at the moment of testing. 相似文献
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Suzdal'nitskiĭ RS Levando VA Emel'ianov BA Sokolov IaA 《Zhurnal mikrobiologii, epidemiologii, i immunobiologii》1999,(5):103-106
The use of the experimental model of the development of acute secondary immunodeficiency, accompanied by the redistribution of immunoglobulins from plasma to blood cells, for evaluating the effect of immunomodulation is substantiated. The preparation of proteolytic enzymes Wobenzym [correction of "Vobenzyme"] has been shown to produce significant and dose-dependent decrease the sorption of immunoglobulins on mouse cells in the process of swimming. 相似文献
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Volianskiĭ IuL Telepneva LG Vasil'ev NV 《Zhurnal mikrobiologii, epidemiologii, i immunobiologii》1999,(1):49-52
In this review the data on the presence of associations between immunogenetic markers and the development of HIV infection are presented. Special attention is given to spatial relationships of genetic determinants, responsible for the synthesis of the components of the complement system on one hand and the genes controlling resistance to the causative agents of opportunistic infections and malignant growth on the other hand. Suggestion is made on close relationship between the specific features of the course of HIV infection and the genetic control, responsible for the synthesis of complement components, in particular the genes making up the HLA system. 相似文献