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121.
Choosing appropriate approaches is a key to successfully using biological control measures to accelerate the recovery of eutrophic waterbodies. In this study, we used three biomanipulation approaches—including introducing filter-feeding bivalves, stocking planktivorous fish, replanting submerged macrophytes—as well as an approach that combined all three of these methods in order to investigate their effects on water quality and plankton communities within simulation experiment systems. The experimental results showed that only stocking filter-feeding bivalves or fish could not significantly control the total algal biomass and water nutrient concentrations compared to those of the controls. The cladoceran biomasses were reduced under the treatments of stocking filter-feeding bivalves or fish. However, replanting macrophytes and a combined biological restoration approach could significantly reduce the algal biomass and the nutrient content, and both of these methods increased cladoceran biomass. The results of factor analysis of ten environmental parameters suggested that a combined biological restoration treatment was the most effective at controlling the algal biomass and reducing the nutrient content. In conclusion, combination of biological restoration measures was the best treatment out of the three treatments that were tested, and we suggest that more whole-lake scale experiments are needed. Additionally, designing a combined approach should not be a simple superposition of individual measures, but the measures should be complementary to each other. 相似文献
122.
Xuan-Ming Zhang Li-Wen Han Shan-Shan Zhang Xiao-Bin Li Qiu-Xia He Jian Han 《Nucleosides, nucleotides & nucleic acids》2019,38(3):203-217
In this study, we investigated the metabonomic profiles of Apostichopus japonicus using an LC-MS-based method in conjunction with multivariate data analysis. Based on the PLS-DA model, 85 differential metabolites (VIP value >1.0) were obtained from viscera and body wall samples. The MS/MS and NMR experiments were used for the qualitative identification of the characteristic peaks. Sphingoid-based nucleoside analogues were the main components in Chinese A. japonicus viscera. Our findings demonstrate that A. japonicus viscera contain a large number of compounds that may have applications as nutraceuticals or pharmaceuticals. 相似文献
123.
【背景】稻水象甲是我国最具危害性的外来入侵物种之一,自1996年传人福建省以来,对当地农民增产、增收及粮食安全生产构成了极大威胁。【方法】依据1996~2008年福建省稻水象甲发生面积数据,结合GIS技术和数据库管理技术,以VisualBasic6.0为开发语言,Access2003为Geodatabase空间数据库、MapObjects2.0为地图开发组件,开发了福建省稻水象甲疫情呈报系统。【结果】本系统实现了稻水象甲疫情实时呈报、基于GIS地理分布查询、专题地图制作等功能。专题地图制作和可扩展性是本系统的两大特点,用户不需要专业的GIS和计算机知识,就可以生成一套适合自己的植物疫情呈报系统,为农业病虫害防治工作提供疫情呈报与GIS查询服务。【结论与意义】本系统为稻水象甲的实时监测、防控工作提供了管理工具;界面友好、操作简单且可扩展性良好,便于基层普及应用。 相似文献
124.
Jian Luo Gayathri Swaminath Sean P. Brown Jane Zhang Qi Guo Michael Chen Kathy Nguyen Thanhvien Tran Lynn Miao Paul J. Dransfield Marc Vimolratana Jonathan B. Houze Simon Wong Maria Toteva Bei Shan Frank Li Run Zhuang Daniel C.-H. Lin 《PloS one》2012,7(10)
Type 2 diabetes is characterized by impaired glucose homeostasis due to defects in insulin secretion, insulin resistance and the incretin response. GPR40 (FFAR1 or FFA1) is a G-protein-coupled receptor (GPCR), primarily expressed in insulin-producing pancreatic β-cells and incretin-producing enteroendocrine cells of the small intestine. Several GPR40 agonists, including AMG 837 and TAK-875, have been disclosed, but no GPR40 synthetic agonists have been reported that engage both the insulinogenic and incretinogenic axes. In this report we provide a molecular explanation and describe the discovery of a unique and potent class of GPR40 full agonists that engages the enteroinsular axis to promote dramatic improvement in glucose control in rodents. GPR40 full agonists AM-1638 and AM-6226 stimulate GLP-1 and GIP secretion from intestinal enteroendocrine cells and increase GSIS from pancreatic islets, leading to enhanced glucose control in the high fat fed, streptozotocin treated and NONcNZO10/LtJ mouse models of type 2 diabetes. The improvement in hyperglycemia by AM-1638 was reduced in the presence of the GLP-1 receptor antagonist Ex(9–39)NH2. 相似文献
125.
Jian Li Guang Yang Min Feng Hailong Liang Jun Zhang Danhong Huang Siyun Deng Yuan Shen 《Biotechnology and Bioprocess Engineering》2012,17(6):1182-1189
The major limitations to non-viral gene delivery are relatively low efficiency and cytotoxicity, which need to be addressed in the design of new vectors. In this study, negatively charged low density lipoproteins (LDL) were coated onto positively charged pVEGF/PEI complexes to form pVEGF/PEI/LDL terplexes by a two-step procedure. The biocompatible LDL was introduced to reduce the cytotoxicity of the gene delivery system and increase its affinity to cells. The successful formation of pVEGF/PEI/ LDL terplexes was confirmed by their near-neutral and slightly negative surface charges. The pVEGF/PEI/LDL terplexes were well-defined sub-micron spherical particles. On the cell viability assay, both of the PEI/LDL combined vector and pVEGF/PEI/LDL terplexes exhibited much lower cytotoxicity to HeLa cells and HUVE cells than those of PEI and pVEGF/PEI complexes, attributed to the shielding effect of the LDL. pEGFP/PEI/LDL terplexes showed significantly higher transfection efficiency in comparison to pEGFP/PEI complexes in serum-containing medium. pVEGF/PEI/LDL terplexes at their optimal N/P ratio and LDL/PEI weigh ratio induced higher expression levels of VEGF protein in HUVE cells than those of pVEGF/PEI complexes. Therefore, the pVEGF/PEI/LDL terplexes could be used as a promising gene delivery system to enhance VEGF protein expression. 相似文献
126.
睫状神经营养因子对体外培养骨骼肌细胞的促增殖效应 总被引:1,自引:1,他引:1
邓小华 《中国应用生理学杂志》2000,16(1):59-63
目的 :探讨睫状神经营养因子 (CNTF)对骨骼肌细胞的直接营养作用 ,从而为神经肌肉系统损伤和退行性病变的治疗提供新的思路。结果 :CNTF可以促进体外培养的L6 TG肌母细胞和新生SD大鼠原代骨骼肌细胞增殖。结论 :CNTF对体外骨骼肌细胞具有营养作用。CNTF的神经和肌肉双重营养性能使其可能在神经肌肉损伤和退行性病变的治疗上发挥重要作用。 相似文献
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共生在水生蕨类植物满江红(又称“红萍”:Azolla)叶腔中的固氮兰细菌曾被认为是一个种满江红鱼腥藻(Anabaena azollae Strasb.).但由于现存的满江红在分类学上有2个亚属,7个种1,对不同满江红叶腔中鱼腥藻的鉴别,多年来引起人们的重视.80年代,鱼腥藻的单克隆抗体和RFLP的研究,发现了它与宿主分类上一定程度的对应关系2,3.90年代以后,Van Coppenolle和Eskew分别以RAPD-PCR和DAF-PCR对从满江红共生体中提取的DNA进行了分析4,5,但后者发现了共生体中藻的DNA对整个PCR产物的干扰作用会影响满江红属本身系统分类.
相似文献
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