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91.
Talita?FA?Ribas Luis?RR?Rodrigues Cleusa?Y?Nagamachi Anderson?JB?Gomes Thayse?CM?Benathar Patricia?CM?O’Brien Fengtang?Yang Malcolm?A?Ferguson-Smith Julio?C?PieczarkaEmail author 《BMC genetics》2013,14(1):119
Background
The genus Micronycteris is a diverse group of phyllostomid bats currently comprising 11 species, with diploid number (2n) ranging from 26 to 40 chromosomes. The karyotypic relationships within Micronycteris and between Micronycteris and other phyllostomids remain poorly understood. The karyotype of Micronycteris hirsuta is of particular interest: three different diploid numbers were reported for this species in South and Central Americas with 2n?=?26, 28 and 30 chromosomes. Although current evidence suggests some geographic differentiation among populations of M. hirsuta based on chromosomal, morphological, and nuclear and mitochondrial DNA markers, the recognition of new species or subspecies has been avoided due to the need for additional data, mainly chromosomal data.Results
We describe two new cytotypes for Micronycteris hirsuta (MHI) (2n?=?26 and 25, NF?=?32), whose differences in diploid number are interpreted as the products of Robertsonian rearrangements. C-banding revealed a small amount of constitutive heterochromatin at the centromere and the NOR was located in the interstitial portion of the short arm of a second pair, confirmed by FISH. Telomeric probes hybridized to the centromeric regions and weakly to telomeric regions of most chromosomes. The G-banding analysis and chromosome painting with whole chromosome probes from Carollia brevicauda (CBR) and Phyllostomus hastatus (PHA) enabled the establishment of genome-wide homologies between MHI, CBR and PHA.Conclusions
The karyotypes of Brazilian specimens of Micronycteris hirsuta described here are new to Micronycteris and reinforce that M. hirsuta does not represent a monotypic taxon. Our results corroborate the hypothesis of karyotypic megaevolution within Micronycteris, and strong evidence for this is that the entire chromosome complement of M. hirsuta was shown to be derivative with respect to species compared in this study.92.
Kit M Lee Renzo Danuser Jens V Stein Delyth Graham Robert JB Nibbs Gerard J Graham 《The EMBO journal》2014,33(21):2564-2580
Macrophages regulate lymphatic vasculature development; however, the molecular mechanisms regulating their recruitment to developing, and adult, lymphatic vascular sites are not known. Here, we report that resting mice deficient for the inflammatory chemokine‐scavenging receptor, ACKR2, display increased lymphatic vessel density in a range of tissues under resting and regenerating conditions. This appears not to alter dendritic cell migration to draining lymph nodes but is associated with enhanced fluid drainage from peripheral tissues and thus with a hypotensive phenotype. Examination of embryonic skin revealed that this lymphatic vessel density phenotype is developmentally established. Further studies indicated that macrophages and the inflammatory CC‐chemokine CCL2, which is scavenged by ACKR2, are associated with this phenotype. Accordingly, mice deficient for the CCL2 signalling receptor, CCR2, displayed a reciprocal phenotype of reduced lymphatic vessel density. Further examination revealed that proximity of pro‐lymphangiogenic macrophages to developing lymphatic vessel surfaces is increased in ACKR2‐deficient mice and reduced in CCR2‐deficient mice. Therefore, these receptors regulate vessel density by reciprocally modulating pro‐lymphangiogenic macrophage recruitment, and proximity, to developing, resting and regenerating lymphatic vessels. 相似文献
93.
Matthew W Blair Sharon JB Knewtson Carolina Astudillo Chee-Ming Li Andrea C Fernandez Michael A Grusak 《BMC plant biology》2010,10(1):215
Background
Iron deficiency anemia is a global problem which often affects women and children of developing countries. Strategy I plants, such as common bean (Phaseolus vulgaris L.) take up iron through a process that involves an iron reduction mechanism in their roots; this reduction is required to convert ferric iron to ferrous iron. Root absorbed iron is critical for the iron nutrition of the plant, and for the delivery of iron to the shoot and ultimately the seeds. The objectives of this study were to determine the variability and inheritance for iron reductase activity in a range of genotypes and in a low × high seed iron cross (DOR364 × G19833), to identify quantitative trait loci (QTL) for this trait, and to assess possible associations with seed iron levels. 相似文献94.
Microbial diversity in Cenozoic sediments recovered from the Lomonosov Ridge in the Central Arctic Basin 总被引:2,自引:0,他引:2
Stephanie R. Forschner Roberta Sheffer David C. Rowley David C. Smith 《Environmental microbiology》2009,11(3):630-639
The current understanding of microbes inhabiting deeply buried marine sediments is based largely on samples collected from continental shelves in tropical and temperate latitudes. The geographical range of marine subsurface coring was expanded during the Integrated Ocean Drilling Program Arctic Coring Expedition (IODP ACEX). This expedition to the ice-covered central Arctic Ocean successfully cored the entire 428 m sediment stack on the Lomonosov Ridge during August and September 2004. The recovered cores vary from siliciclastic sediment low in organic carbon (< 0.2%) to organic rich (∼3%) black sediments that rapidly accumulated in the early middle Eocene. Three geochemical environments were characterized based on chemical analyses of porewater: an upper ammonium oxidation zone, a carbonate dissolution zone and a deep (> 200 m below sea floor) sulfate reduction zone. The diversity of microbes within each zone was assessed using 16S rRNA phylogenetic markers. Bacterial 16S rRNA genes were successfully amplified from each of the biogeochemical zones, while archaea was only amplified from the deep sulfate reduction zone. The microbial communities at each zone are phylogenetically different and are most closely related to those from other deep subsurface environments. 相似文献
95.
Ryosuke Shirasaki Geoffrey M. Matthews Sara Gandolfi Ricardo de Matos Simoes Dennis L. Buckley Joseline Raja Vora Quinlan L. Sievers Johanna B. Brüggenthies Olga Dashevsky Haley Poarch Huihui Tang Megan A. Bariteau Michal Sheffer Yiguo Hu Sondra L. Downey-Kopyscinski Paul J. Hengeveld Brian J. Glassner Eugen Dhimolea Constantine S. Mitsiades 《Cell reports》2021,34(1):108532
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96.
97.
The sequences of the linked alpha 2- and alpha 1-globin genes of the equine
BI and BII haplotypes are greater than 99% identical within a 1.2-kb region
extending from approximately 75 bp upstream of the putative cap site to a
point approximately 150 bp 3' to the poly A addition signal. Differences
between the alpha 2 and alpha 1 genes that are common to both haplotypes
indicate that a major gene conversion occurred approximately 12 Myr ago and
that this has been followed by shorter, more localized, conversions.
Interhaplotype (allelic) comparisons at the alpha loci suggest that the BI
and BII haplotypes have probably existed independently greater than or
equal to 0.5 Myr and that the alpha 1 genes may have undergone a recent
interchromosomal gene conversion.
相似文献
98.
99.
100.
Daphna Uni David Lerner Izak Smit Duduzile Mzimba Efrat Sheffer Gidon Winters Tamir Klein 《American journal of botany》2023,110(2):e16132